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Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共215条，第1-10条 帮助

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Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 17
作者:  Lan, Yaohan;  Peng, Xia;  Ji, Yinchun;  Su, Yi;  Duan, Wenhu
  |  收藏  |  浏览/下载：9/0  |  提交时间：2024/02/27
Discovery, Optimization, and Evaluation of Novel Pyridin-2(1H)-one Analogues as Potent TRK Inhibitors for Cancer Treatment 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1168-1183
作者:  Xu, Zichao;  Peng, Xia;  Zhang, Renjie;  Ji, Yinchun;  You, Mengke
  |  收藏  |  浏览/下载：10/0  |  提交时间：2024/02/27
Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRASG12D 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1147-1167
作者:  Zhou, Chuan;  Fan, Zisheng;  Gu, Yuejiao;  Ge, Zhiming;  Tao, Zhaofan
  |  收藏  |  浏览/下载：10/0  |  提交时间：2024/02/27
NIR-II fluorescence-guided liver cancer surgery by a small molecular HDAC6 targeting probe 期刊论文  OAI收割
EBIOMEDICINE, 2023, 卷号: 98, 页码: 18
作者:  Wang, Bo;  Tang, Chu;  Lin, En;  Jia, Xiaohua;  Xie, Ganyuan
  |  收藏  |  浏览/下载：14/0  |  提交时间：2024/02/22
LINC00955 suppresses colorectal cancer growth by acting as a molecular scaffold of TRIM25 and Sp1 to Inhibit DNMT3B-mediated methylation of the PHIP promoter 期刊论文  OAI收割
BMC CANCER, 2023, 卷号: 23, 期号: 1, 页码: 20
作者:  Ren, Ganglin;  Li, Hongyan;  Hong, Dan;  Hu, Fangyu;  Jin, Rongjia
  |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/08
Oral Delivery of Gemcitabine-Loaded Glycocholic Acid-Modified Micelles for Cancer Therapy 期刊论文  OAI收割
ACS NANO, 2023, 卷号: 17, 期号: 18, 页码: 18074-18088
作者:  Zang, Wenqing;  Gao, Duo;  Yu, Miaorong;  Long, Manmei;  Zhang, Zhuan
  |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/08
Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR plus Human Prostate Cancer 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 18, 页码: 13280-13303
作者:  Xiang, Weiguo;  Zhao, Lijie;  Han, Xin;  Xu, Tianfeng;  Kregel, Steven
  |  收藏  |  浏览/下载：9/0  |  提交时间：2023/12/08
Fibroblast Activation Protein Targeting Probe with Gly-Pro Sequence for PET of Glioblastoma 期刊论文  OAI收割
MOLECULAR PHARMACEUTICS, 2023, 卷号: 20, 期号: 8, 页码: 4120-4128
作者:  Lai, Chaoquan;  Cao, Rui;  Li, Renda;  He, Chunfeng;  Wang, Xiao
  |  收藏  |  浏览/下载：20/0  |  提交时间：2023/10/17
Discovery of (S)-N-(2-Amino-4-fluorophenyl)-4-(1-(3-(4-((dimethylamino)methyl)phenyl)-6-oxopyridazin-1(6H)-yl)ethyl)benzamide as Potent Class I Selective HDAC Inhibitor for Oral Anticancer Drug Candidate 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 10, 页码: 7016-7037
作者:  Li, Daqiang;  Zhang, Zhuo;  Li, Yalei;  Wang, Xinyi;  Zhong, Hanyue
  |  收藏  |  浏览/下载：18/0  |  提交时间：2023/10/17
Celastrol suppresses colorectal cancer via covalent targeting peroxiredoxin 1 期刊论文  OAI收割
Signal Transduction and Targeted Therapy, 2023, 卷号: 8, 期号: 3, 页码: 1159-1174
作者:  Xu, Heng;  Zhao, Hongfang;  Ding, Chunyong;  Jiang, Defang;  Zhao, Zijie
  |  收藏  |  浏览/下载：10/0  |  提交时间：2024/03/27