中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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  • 上海药物研究所 [14]
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Discovery of Pteridine-7(8H)-one Derivatives as Potent and Selective Inhibitors of Bruton's Tyrosine Kinase (BTK) 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 3, 页码: 2694-2709
作者:  
Dou, Dou;  Diao, Yanyan;  Sha, Wenjie;  Su, Rongrong;  Tong, Linjiang
  |  收藏  |  浏览/下载:24/0  |  提交时间:2022/08/16
Discovery of Potent and Noncovalent Reversible EGFR Kinase Inhibitors of EGFR(L858R/T790M/C797S) 期刊论文  OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 10, 期号: 6, 页码: 869-873
作者:  
Li, Qiannan;  Zhang, Tao;  Li, Shiliang;  Tong, Linjiang;  Li, Junyu
  |  收藏  |  浏览/下载:59/0  |  提交时间:2020/07/01
EGFR  mutant  inhibitor  C797S  
Design, Synthesis, and Biological Evaluation of Pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-diones as Potent and Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors against L858R/T790M Resistance Mutation 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 13, 页码: 5609-5622
作者:  
Hao, Yongjia;  Lyu, Jiankun;  Qu, Rong;  Tong, Yi;  Sun, Deheng
  |  收藏  |  浏览/下载:61/0  |  提交时间:2019/01/08
TRPM7 in CHBP-induced renoprotection upon ischemia reperfusion-related injury 期刊论文  OAI收割
SCIENTIFIC REPORTS, 2018, 卷号: 8
作者:  
Liu, Aifen;  Wu, Jing;  Yang, Cheng;  Wu, Yuanyuan;  Zhang, Yufang
  |  收藏  |  浏览/下载:44/0  |  提交时间:2019/01/08
Discovery and biological evaluation of N5-substituted 6,7-dioxo-6,7-dihydropteridine derivatives as potent Bruton's tyrosine kinase inhibitors 期刊论文  OAI收割
MEDCHEMCOMM, 2018, 卷号: 9, 期号: 4, 页码: 697-704
作者:  
Chen, Haiyang;  Song, Peiran;  Diao, Yanyan;  Hao, Yongjia;  Dou, Dou
  |  收藏  |  浏览/下载:29/0  |  提交时间:2019/01/08
Design, Synthesis, and Evaluation of Ribose-Modified Anilinopyrimidine Derivatives as EGFR Tyrosine Kinase Inhibitors 期刊论文  OAI收割
FRONTIERS IN CHEMISTRY, 2017, 卷号: 5
作者:  
Hu, Xiuqin;  Wang, Disha;  Tong, Yi;  Tong, Linjiang;  Wang, Xia
  |  收藏  |  浏览/下载:60/0  |  提交时间:2019/01/08
Structure-Guided Design of C4-alkyl-1,4-dihydro-2H-pyrimido[4,5-d][1,3]oxazin-2-ones as Potent and Mutant-Selective Epidermal Growth Factor Receptor (EGFR) L858R/T790M Inhibitors 期刊论文  OAI收割
SCIENTIFIC REPORTS, 2017, 卷号: 7
作者:  
Hao, Yongjia;  Lyu, Jiankun;  Qu, Rong;  Sun, Deheng;  Zhao, Zhenjiang
  |  收藏  |  浏览/下载:32/0  |  提交时间:2019/01/08
Discovery and Structural Optimization of N5-Substituted 6,7-Dioxo-6,7-dihydropteridines as Potent and Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors against L858R/T790M Resistance Mutation 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 15, 页码: 7111-7124
作者:  
Hao, Yongjia;  Wang, Xia;  Zhang, Tao;  Sun, Deheng;  Tong, Yi
  |  收藏  |  浏览/下载:32/0  |  提交时间:2019/01/08
Discovery and Rational Design of Natural-Product-Derived 2-Phenyl-3,4-dihydro-2H-benzo[f]chromen-3-amine Analogs as Novel and Potent Dipeptidyl Peptidase 4 (DPP-4) Inhibitors for the Treatment of Type 2 Diabetes 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 14, 页码: 6772-6790
作者:  
Li, Shiliang;  Xu, Hongling;  Cui, Shichao;  Wu, Fangshu;  Zhang, Youli
  |  收藏  |  浏览/下载:27/0  |  提交时间:2019/01/08
EFFECTS OF ERYTHROPOIETIN DERIVED PEPTIDE CHBP ON ISCHEMIA REPERFUSION AND CYCLOSPORINE A INDUCED RENAL INJURY IN MICE 会议论文  OAI收割
作者:  
Zhang, Yufang;  Wu, Yuanyuan;  Yang, Cheng;  Liu, Feng;  Zhang, Yiwen
  |  收藏  |  浏览/下载:23/0  |  提交时间:2019/01/08