中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [8]
海洋研究所 [7]
上海生物化学与细胞生... [4]
昆明动物研究所 [3]
水生生物研究所 [2]
计算技术研究所 [1]
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OAI收割 [28]
iSwitch采集 [2]
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期刊论文 [28]
会议论文 [1]
学位论文 [1]
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2022 [3]
2020 [1]
2018 [4]
2017 [2]
2016 [2]
2015 [5]
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Immunology [3]
Fisheries [2]
Marine & F... [2]
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Development of a traditional Chinese medicine-based agent for the treatment of cancer cachexia
期刊论文
OAI收割
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2022
作者:
Wu, Kun-Chang
;
Chu, Po-Chen
;
Cheng, Yu-Jung
;
Li, Chia-Ing
;
Tian, Jingkui
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/12/23
Cachexia
Traditional Chinese medicine
Muscle atrophy
C-26 tumour-bearing model
Caenorhabditis elegans model
Molecular insights into ligand recognition and activation of chemokine receptors CCR2 and CCR3
期刊论文
OAI收割
CELL DISCOVERY, 2022, 卷号: 8, 期号: 1, 页码: 11
作者:
Shao, Zhehua
;
Tan, Yangxia
;
Shen, Qingya
;
Hou, Li
;
Yao, Bingpeng
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/08/16
Artemisinin derivative TPN10466 suppresses immune cell migration and Th1/Th17 differentiation to ameliorate disease severity in experimental autoimmune encephalomyelitis
期刊论文
OAI收割
CELLULAR IMMUNOLOGY, 2022, 卷号: 373, 页码: 10
作者:
Liu, Guangyu
;
Jiang, Xiangrui
;
Han, Mengyao
;
Lv, Jie
;
Zhuang, Wei
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/08/16
EAE
Cell migration
Th1
Th17 differentiation
Revealing the Positive Binding Cooperativity Mechanism between the Orthosteric and the Allosteric Antagonists of CCR2 by Metadynamics and Gaussian Accelerated Molecular Dynamics Simulations
期刊论文
OAI收割
ACS CHEMICAL NEUROSCIENCE, 2020, 卷号: 11, 期号: 4, 页码: 628-637
作者:
An, Xiaoli
;
Bai, Qifeng
;
Bing, Zhitong
;
Liu, Hongli
;
Zhang, Qianqian
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/01/18
CC chemokine receptor 2
orthosteric antagonist
allosteric antagonist
binding cooperativity
metadynamics simulation
Gaussian accelerated MD simulation
Structure-Based Design of 1-Heteroary1-1,3-propanediamine Derivatives as a Novel Series of CC-Chemokine Receptor 5 Antagonists
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 21, 页码: 9621-9636
作者:
Peng, Panfeng
;
Chen, Huan
;
Zhu, Ya
;
Wang, Zhilong
;
Li, Jian
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2019/01/08
Bridging Systemic Immunity with Gastrointestinal Immune Responses via Oil-in-Polymer Capsules
期刊论文
OAI收割
ADVANCED MATERIALS, 2018, 卷号: 30, 期号: 31, 页码: 8
作者:
Xia, Yufei
;
Wu, Jie
;
Du, Yiqun
;
Miao, Chunyu
;
Su, Zhiguo
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2018/10/11
Gastrointestinal Infections
Gut Tropism
Mucosal Immunity
Oil-in-polymer Capsules
Retinoic Acid
Discovery and synthesis of 6,7,8,9-tetrahydro-5H-pyrido[4,3-c]azepin-5-one-based novel chemotype CCR2 antagonists via scaffold hopping strategy
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 12, 页码: 3559-3572
作者:
Qin, Li-Huai
;
Wang, Zhi-Long
;
Xie, Xin
;
Long, Ya-Qiu
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
6,7,8,9-Tetrahydro-5H-pyrido[43-c]azepin-5-one
3,4-Dihydro-2,6-naphthyridin-1(2H)-one
CCR2 antagonist
Scaffold hopping
Structure-activity relationship
Selectivity of CCR2 over CCR5
CC chemokine receptor 7 promotes triple-negative breast cancer growth and metastasis
期刊论文
OAI收割
Acta Biochimica et Biophysica Sinica, 2018, 卷号: 50, 期号: 9, 页码: 835–842
作者:
Zehua Wang
;
Jiao Wu
;
Runxiang Yang
;
Jianing Liu
;
Yang Wang
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2018/09/28
Ccr7
Triple-negative Breast Cancer
Metastasis
Molecular characterization and expression analysis of four fish-specific CC chemokine receptors CCR4La, CCR4Lc1, CCR4Lc2 and CCR11 in rainbow trout (Oncorhynchus mykiss)
会议论文
OAI收割
Santiago de Compostela, SPAIN, JUN 21-27, 2015
作者:
Qi, Zhitao
;
Holland, Jason W.
;
Jiang, Yousheng
;
Secombes, Christopher J.
;
Nie, Pin
  |  
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2019/08/01
Rainbow trout
CC chemokine receptor
CCR4La
CCR4Lc
CCR11
Expression
Modulation
Pro-inflammatory cytokine
Bacterial infection
Parasitic infection
Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist RevealsMechanisms of Chemokine Recognition and Molecular Mimicry by HIV
期刊论文
OAI收割
IMMUNITY, 2017, 卷号: 46, 期号: 6, 页码: 1005-+
作者:
Zheng, Yi
;
Han, Gye Won
;
Abagyan, Ruben
;
Wu, Beili
;
Stevens, Raymond C.
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08