中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Discovery of novel SOS1 inhibitors using machine learning
期刊论文
OAI收割
RSC MEDICINAL CHEMISTRY, 2024, 卷号: 15, 期号: 4, 页码: 1392-1403
作者:
Duo, Lihui
;
Chen, Yi
;
Liu, Qiupei
;
Ma, Zhangyi
;
Farjudian, Amin
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
D3EGFR: a webserver for deep learning-guided drug sensitivity prediction and drug response information retrieval for EGFR mutation-driven lung cancer
期刊论文
OAI收割
BRIEFINGS IN BIOINFORMATICS, 2024, 卷号: 25, 期号: 3, 页码: 10
作者:
Shi, Yulong
;
Li, Chongwu
;
Zhang, Xinben
;
Peng, Cheng
;
Sun, Peng
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2024/05/07
lung cancer
EGFR mutation
drug sensitivity prediction
patient case database
deep learning
JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
期刊论文
OAI收割
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:
Lu, Xuxiu
;
Yu, Rilei
;
Li, Zhen
;
Yang, Mengke
;
Dai, Jiajia
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/04/07
Acquired resistance
Cancer
NSCLC
JC-010a
SHP2
SIBP-03, a novel anti-HER3 antibody, exerts antitumor effects and synergizes with EGFR- and HER2-targeted drugs
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 10
作者:
Li, Wen-jing
;
Xie, Cheng-ying
;
Zhu, Xi
;
Tang, Jiao
;
Wang, Lei
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2024/02/19
SIBP-03
HER3
HER3-targeted therapy
neuregulin 1
EGFR
HER2
Epigenetic-based combination therapy and liposomal codelivery overcomes osimertinib-resistant NSCLC via repolarizing tumor-associated macrophages
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Lin, Ting-ting
;
Xiong, Wei
;
Chen, Gui-hua
;
He, Yang
;
Long, Li
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/26
osimertinib resistance
targeted drug delivery
liposomes
panobinostat
tumor-associated macrophage
combination therapy
Synthesis, and biological evaluation of EGFR/HER2-NAMPT conjugates for tumor treatment
期刊论文
OAI收割
MOLECULAR DIVERSITY, 2023, 页码: 20
作者:
Ding, Mengyuan
;
Shen, Qianqian
;
Lu, Wei
;
Zhu, Shulei
  |  
收藏
  |  
浏览/下载:92/0
  |  
提交时间:2023/10/17
EGFR
HER2
NAMPT
Resistance
Selectivity
Molecular docking
Peptide-functionalized therapeutic nanoplatform for treatment orthotopic triple negative breast cancer and bone metastasis
期刊论文
OAI收割
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2023, 卷号: 50, 页码: 102669
作者:
Li, Daifeng
;
Ma, Shengnan
;
Xu, Denghui
;
Meng, Xiaocao
;
Lei, Ningjing
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/03/27
Triple-negative breast cancer
Epidermal growth factor receptor
Peptide-functionalized therapy
Peptide self-assembly
Nanoplatform
SYK-mediated epithelial cell state is associated with response to c-Met inhibitors in c-Met-overexpressing lung cancer
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 13
作者:
Zhou, Ji
;
Zhang, Xu-Chao
;
Xue, Shan
;
Dai, Mengdi
;
Wang, Yueliang
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Design, Synthesis, and Evaluation of (R)-8-((Tetrahydrofuran-2-yl)methyl)pyrido[2,3-d]pyrimidin-7-ones as Novel Selective ACK1 Inhibitors to Combat Acquired Resistance to the Third-Generation EGFR Inhibitor
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 17
作者:
Li, Qian
;
Zhang, Tao
;
Song, Peiran
;
Tong, Linjiang
;
Feng, Fang
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/10/17
Anxiolytic-like effect of Suanzaoren-Wuweizi herb-pair and evidence for the involvement of the monoaminergic system in mice based on network pharmacology
期刊论文
OAI收割
BMC COMPLEMENTARY MEDICINE AND THERAPIES, 2023, 卷号: 23, 期号: 1, 页码: 17
作者:
Liu, Jie
;
Shi, Jin-Li
;
Guo, Jian-You
;
Chen, Yi
;
Ma, Xiao-Jie
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2023/03/01
Suanzaoren-Wuweizi
Anxiolytic-like effect
Mechanism
Monoaminergic system
Network pharmacology