中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
南海海洋研究所 [4]
昆明植物研究所 [4]
上海营养与健康研究所 [3]
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大连化学物理研究所 [2]
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期刊论文 [33]
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2024 [1]
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Functional analysis of CYP71AV1 reveals the evolutionary landscape of artemisinin biosynthesis
期刊论文
OAI收割
FRONTIERS IN PLANT SCIENCE, 2024, 卷号: 15, 页码: 9
作者:
Chen, Fang-Yan
;
Mu, Qiu-Yan
;
Xu, Bing-Yi
;
Lei, Yu-Chen
;
Liu, Hui-Ying
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/05/07
artemisinin
Asteraceae sesquiterpene lactone
cytochrome P450 monooxygenases
amorpha-4
11-diene oxidase
germacrene A oxidase
molecular evolution
loss-of-function event
Catalytic site flexibility facilitates the substrate and catalytic promiscuity of Vibrio dual lipase/transferase
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 11
作者:
Wang, Chongyang
;
Liu, Changshui
;
Zhu, Xiaochuan
;
Peng, Quancai
;
Ma, Qingjun
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/13
Molecular insights into the catalytic promiscuity of a bacterial diterpene synthase
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15
作者:
Li, Zhong
;
Zhang, Lilan
;
Xu, Kangwei
;
Jiang, Yuanyuan
;
Du, Jieke
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/13
Unraveling the serial glycosylation in the biosynthesis of steroidal saponins in the medicinal plant Paris polyphylla and their antifungal action
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 11, 页码: 4638-4654
作者:
Chen,Yuegui
;
Yan,Qin
;
Ji,Yunheng
;
Bai,Xue
;
Li,Desen
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/09
Paris polyphylla var. yunnanensis
Steroidal saponins
Glycosyltransferases
Sugar chain elongation
Antifungal activity
CHEMICAL-CONSTITUENTS
GLYCOSYLTRANSFERASES
GLYCOSIDES
DIVERSITY
CULTIVATION
PATHWAY
FAMILY
PARTS
GENUS
STEP
Characterization and protein engineering of glycosyltransferases for the biosynthesis of diverse hepatoprotective cycloartane-type saponins in Astragalus membranaceus
期刊论文
OAI收割
PLANT BIOTECHNOLOGY JOURNAL, 2023
作者:
Chen,Kuan
;
Zhang,Meng
;
Gao,Baihan
;
Hasan,Aobulikasimu
;
Li,Junhao
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/09
astragalosides
biosynthesis
glycosyltransferases
protein engineering
Astragalus membranaceus
FUNCTIONAL-CHARACTERIZATION
UDP-GLYCOSYLTRANSFERASES
CARBON-TETRACHLORIDE
PROTOPANAXATRIOL
PHARMACOLOGY
GENERATION
CHEMISTRY
ACCURACY
PATHWAY
Insights into divalent cation regulation and G(13)-coupling of orphan receptor GPR35
期刊论文
OAI收割
CELL DISCOVERY, 2022, 卷号: 8, 期号: 1, 页码: 12
作者:
Duan, Jia
;
Liu, Qiufeng
;
Yuan, Qingning
;
Ji, Yujie
;
Zhu, Shengnan
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
GPCRs steer G(i) and G(s) selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors
期刊论文
OAI收割
MOLECULAR CELL, 2022, 卷号: 82, 期号: 14, 页码: 2681-+
作者:
Huang, Sijie
;
Xu, Peiyu
;
Shen, Dan-Dan
;
Simon, Icaro A.
;
Mao, Chunyou
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/09/30
Dynamic reconfiguration of human brain networks across altered states of consciousness
期刊论文
OAI收割
BEHAVIOURAL BRAIN RESEARCH, 2022, 卷号: 419, 页码: 11
作者:
Liu, Haiyang
;
Hu, Ke
;
Peng, Yingjie
;
Tian, Xiaohan
;
Wang, Meng
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/06/06
Functional magnetic resonance imaging
Multilayer networks
Dynamic functional connectivity
Consciousness
Sedation
Dexmedetomidine
Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor
期刊论文
OAI收割
NATURE CHEMICAL BIOLOGY, 2021, 卷号: 17, 期号: 12, 页码: 1238-1244
作者:
Liu, Qiufeng
;
Yang, Dehua
;
Zhuang, Youwen
;
Croll, Tristan I.
;
Cai, Xiaoqing
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/03/22
a Receptor
Structural Basis
Binding-site
Cck1 Receptor
Agonist
Activation
Mechanism
Optimization
Discovery
Rat
An extremely promiscuous terpenoid synthase from the Lamiaceae plant Colquhounia coccinea var. mollis catalyzes the formation of sester-/di-/sesqui-/mono-terpenoids
期刊论文
OAI收割
PLANT COMMUNICATIONS, 2021, 卷号: 2, 期号: 5, 页码: 100233
作者:
Li,De-Sen
;
Hua,Juan
;
Luo,Shi-Hong
;
Liu,Yan-Chun
;
Chen,Yue-Gui
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/04/02
terpenoid diversity
terpenoid synthase
promiscuous enzyme
sester-/di-/sesqui-/mono-terpenoids
Colquhounia coccinea var
mollis
GERANYLFARNESYL DIPHOSPHATE SYNTHASE
GLANDULAR TRICHOMES
DITERPENE SYNTHASE
LEUCOSCEPTRUM-CANUM
IDENTIFICATION
BRASSICACEAE
BIOLOGY
FAMILY
HARBOR
GENES