中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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机构
上海药物研究所 [17]
上海生物化学与细胞生... [3]
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OAI收割 [36]
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期刊论文 [35]
学位论文 [1]
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2024 [1]
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Identification of YCH2823 as a novel USP7 inhibitor for cancer therapy
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2024, 卷号: 222, 页码: 11
作者:
Cheng, Yong -Jun
;
Zhuang, Zhen
;
Miao, Yu -Ling
;
Song, Shan -Shan
;
Bao, Xu-Bin
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
YCH2823
USP7 inhibitor
FT671
BCL6
mTOR inhibitor
Deubiquitylating Enzymes in Cancer and Immunity
期刊论文
OAI收割
ADVANCED SCIENCE, 2023, 页码: 37
作者:
Ren, Jiang
;
Yu, Peng
;
Liu, Sijia
;
Li, Ran
;
Niu, Xin
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/08
cancer
deubiquitylating enzymes (DUBs)
immunity
therapeutic approach
Elastic network models and molecular dynamic simulations reveal the molecular basis of allosteric regulation in ubiquitin-specific protease 7 (USP7)
期刊论文
OAI收割
COMPUTERS IN BIOLOGY AND MEDICINE, 2023, 卷号: 162, 页码: 10
作者:
Xu, Jing
;
Wang, Yiran
;
Zhang, Jiali
;
Abdelmoneim, Amr Abbas
;
Liang, Zhongjie
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/10/17
USP7
Allosteric regulation
Elastic network models
Molecular dynamics simulations
Discovery of a Potent and Selective Degrader for USP7
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 卷号: 61, 期号: 33, 页码: e202204395
作者:
Pei, Yuan
;
Fu, Jingfeng
;
Shi, Yunkai
;
Zhang, Mengmeng
;
Luo, Guanghao
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/21
Apoptotic Pathway
Mutant p53
p53 Mutant Cancer Cells
PROTAC
USP7 Degrader
Discovery of Potent Small-Molecule USP8 Inhibitors for the Treatment of Breast Cancer through Regulating ERα Expression
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 13, 页码: 8914-8932
作者:
Tian, Yucheng
;
Liu, Kang
;
Liu, Ruoyi
;
Qiu, Zhixia
;
Xu, Yifan
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/03/21
Ribonucleotide reductase holoenzyme inhibitor COH29 interacts with deubiquitinase ubiquitin-specific protease 2 and downregulates its substrate protein cyclin D1
期刊论文
OAI收割
FASEB JOURNAL, 2022, 卷号: 36, 期号: 5, 页码: 21
作者:
Zhu, Mengying
;
Wang, Hui
;
Ding, Yiluan
;
Yang, Yuanyuan
;
Xu, Zhuo
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2022/06/15
COH29
cyclin D1
deubiquitinase
inhibitor
USP2
Monoterpene indole alkaloids from Melodinus cochinchinensis (Lour.) Merr.
期刊论文
OAI收割
FITOTERAPIA, 2022, 卷号: 157, 页码: 4
作者:
Wang, Xiao-Feng
;
Wei, Ren-Jie
;
Fang, Qiang-Qiang
;
He, Wan-Ying
;
Jiang, Kun
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/06/15
HAUSP promoted the growth of glioma cells in vitro and in vivo via stabilizing NANOG
期刊论文
OAI收割
PATHOLOGY RESEARCH AND PRACTICE, 2020, 卷号: 216
作者:
Cheng, Chuan-dong
;
Dong, Yong-fei
;
Niu, Wan-xiang
;
Niu, Chao-shi
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/11/26
HAUSP
Glioma cell
NANOG
Cellular behavior
Nude mice xenograft
pSILAC method coupled with two complementary digestion approaches reveals PRPF39 as a new E7070-dependent DCAF15 substrate
期刊论文
OAI收割
JOURNAL OF PROTEOMICS, 2020, 卷号: 210, 页码: 11
作者:
Jia, Xinglong
;
Pan, Lulu
;
Zhu, Mingrui
;
Hu, Hao
;
Zhai, Linhui
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
E7070
pSILAC
LysC-Trypsin
LysN-LysArgiNase
PRPF39
DCAF15
Degradation
USP9X stabilizes BRCA1 and confers resistance to DNA-damaging agents in human cancer cells
期刊论文
OAI收割
CANCER MEDICINE, 2019, 卷号: 8, 期号: 15, 页码: 6730-6740
作者:
Lu, Qin
;
Zhang, Fang-Lin
;
Lu, Da-Yun
;
Shao, Zhi-Ming
;
Li, Da-Qiang
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
BRCA1
breast cancer
deubiquitinase
PARP inhibitor
USP9X