中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [227]
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DNA-PK-Mediated Cytoplasmic DNA Sensing Stimulates Glycolysis to Promote Lung Squamous Cell Carcinoma Malignancy and Chemoresistance
期刊论文
OAI收割
CANCER RESEARCH, 2024, 卷号: 84, 期号: 5, 页码: 688-702
作者:
Wang, Hui
;
Zhang, Yanyang
;
Tian, Yu
;
Yang, Wanlin
;
Wang, Yan
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/05/07
Tetraspanin CD53 regulates peripheral blood leucocytes vitality and pathogen infection in turbot
(Scophthalmus
maximus)
期刊论文
OAI收割
FISH & SHELLFISH IMMUNOLOGY, 2024, 卷号: 146, 页码: 8
作者:
Zhang, Jian
;
Zhou, Dandan
;
Zhang, Binzhe
;
Li, Xuepeng
;
Jiao, Xudong
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Scophthalmus maximus
Tetraspanin
CD53
Immunoregulation
Antibody ligation
Discovery, Optimization, and Evaluation of Novel Pyridin-2(1
H
)-one Analogues as Potent TRK Inhibitors for Cancer Treatment
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1168-1183
作者:
Xu, Zichao
;
Peng, Xia
;
Zhang, Renjie
;
Ji, Yinchun
;
You, Mengke
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/02/27
Design and synthesis of cantharidin derivative DCZ5418 as a TRIP13 inhibitor with anti-multiple myeloma activity
in
vitro
and
in
vivo
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 98, 页码: 7
作者:
Dong, Sanfeng
;
Hu, Ke
;
Shi, Yulong
;
Wang, Guanli
;
Yu, Dandan
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/02/19
Multiple myeloma
TRIP13 inhibitor
Cantharidin
DCZ5418
DCZ0415
Opportunities and challenges of fucoidan for tumors therapy
期刊论文
OAI收割
CARBOHYDRATE POLYMERS, 2024, 卷号: 324, 页码: 13
作者:
Yu, Haoyu
;
Zhang, Quanbin
;
Farooqi, Ammad Ahmad
;
Wang, Jing
;
Yue, Yang
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/04/07
Brown algae
Fucoidan
Structure
Anti-tumor
Improvement of the Antioxidant and Antitumor Activities of Benzimidazole-Chitosan Quaternary Ammonium Salt on Drug Delivery Nanogels
期刊论文
OAI收割
MARINE DRUGS, 2024, 卷号: 22, 期号: 1, 页码: 21
作者:
Ma, Bing
;
Li, Qing
;
Zhang, Jingjing
;
Mi, Yingqi
;
Tan, Wenqiang
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/07
benzimidazole-chitosan quaternary ammonium salt
acidic-responsive nanogels
antioxidant activity
antitumor activity
The combination of calreticulin-targeting L-ASNase and anti-PD-L1 antibody modulates the tumor immune microenvironment to synergistically enhance the antitumor efficacy of radiotherapy
期刊论文
OAI收割
THERANOSTICS, 2024, 卷号: 14, 期号: 3, 页码: 1195-1211
作者:
Zhang, Ying
;
Akhil, Venu
;
Seo, Ho Seong
;
Park, Hae Ran
;
Kim, Soo Hyun
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/05/07
Cancer radiotherapy
immunogenic cell death
calreticulin
L-ASNase
reactive oxygen species
immune checkpoint inhibitor
Targeting ST8SIA6-AS1 counteracts KRAS
G12C
inhibitor resistance through abolishing the reciprocal activation of PLK1/c-Myc signaling
期刊论文
OAI收割
EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2023, 卷号: 12, 期号: 1, 页码: 22
作者:
Wang, Yafang
;
Yao, Mingyue
;
Li, Cheng
;
Yang, Kexin
;
Qin, Xiaolong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/26
KRAS(G12C)
c-Myc
PLK1
LncRNA
ST8SIA6-AS1
Drug resistance
K252a inhibition of sperm viability for efficient crossbreeding of hermaphroditic bivalves
期刊论文
OAI收割
AQUACULTURE, 2023, 卷号: 577, 页码: 9
作者:
Liu, Tian
;
Wei, Huilan
;
Zhang, Lijing
;
Liu, Liangjie
;
Li, Yajuan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/26
K252a
Sperm motility
Crossbreeding
Simultaneous hermaphrodite
Argopecten irradians
Argopecten purpuratus
Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:
Liu, Yingqiang
;
Zhan, Zhengsheng
;
Kang, Zhuang
;
Li, Mengyuan
;
Lv, Yongcong
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/01/26
Small molecule inhibitor
Tumor microenvironment
Immune-checkpoint
immune-deficient mouse models
including temozolomide (TMZ) insensitive tumors. Notably