中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [11]
烟台海岸带研究所 [3]
西北高原生物研究所 [2]
过程工程研究所 [2]
地质与地球物理研究所 [1]
合肥物质科学研究院 [1]
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采集方式
OAI收割 [20]
内容类型
期刊论文 [20]
发表日期
2023 [20]
学科主题
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Targeting ST8SIA6-AS1 counteracts KRAS
G12C
inhibitor resistance through abolishing the reciprocal activation of PLK1/c-Myc signaling
期刊论文
OAI收割
EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2023, 卷号: 12, 期号: 1, 页码: 22
作者:
Wang, Yafang
;
Yao, Mingyue
;
Li, Cheng
;
Yang, Kexin
;
Qin, Xiaolong
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/01/26
KRAS(G12C)
c-Myc
PLK1
LncRNA
ST8SIA6-AS1
Drug resistance
K252a inhibition of sperm viability for efficient crossbreeding of hermaphroditic bivalves
期刊论文
OAI收割
AQUACULTURE, 2023, 卷号: 577, 页码: 9
作者:
Liu, Tian
;
Wei, Huilan
;
Zhang, Lijing
;
Liu, Liangjie
;
Li, Yajuan
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/26
K252a
Sperm motility
Crossbreeding
Simultaneous hermaphrodite
Argopecten irradians
Argopecten purpuratus
Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:
Liu, Yingqiang
;
Zhan, Zhengsheng
;
Kang, Zhuang
;
Li, Mengyuan
;
Lv, Yongcong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/26
Small molecule inhibitor
Tumor microenvironment
Immune-checkpoint
immune-deficient mouse models
including temozolomide (TMZ) insensitive tumors. Notably
Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933
作者:
Fang, Feifei
;
Dai, Yang
;
Wang, Hao
;
Ji, Yinchun
;
Liang, Xuewu
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/01/26
derivatives
Antitumor drug development
Potential AXL inhibitor
Antitumor activity
Structure-based drug design
Fused-pyrazolone carboxamide
Preparation and Antioxidant Activity of New Carboxymethyl Chitosan Derivatives Bearing Quinoline Groups
期刊论文
OAI收割
MARINE DRUGS, 2023, 卷号: 21, 期号: 12, 页码: 21
作者:
Wang, Linqing
;
Guo, Rui
;
Liang, Xiaorui
;
Ji, Yuting
;
Zhang, Jingjing
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/01/26
antioxidant activity
carboxymethyl chitosan derivatives
quinoline
Dihydrocelastrol induces antitumor activity and enhances the sensitivity of bortezomib in resistant multiple myeloma by inhibiting STAT3-dependent PSMB5 regulation
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2023, 卷号: 55, 期号: 12, 页码: 1884-1891
作者:
Jin, Shuhan
;
Li, Bo
;
Zhang, Bibo
;
Gao, Xuejie
;
Jia, Xinyan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/02/27
dihydrocelastrol
multiple myeloma
JAK2/STAT3
PSMB5
bortezomib resistance
Inhibiting Endothelial Cell-Mediated T Lymphocyte Apoptosis with Integrin-Targeting Peptide-Drug Conjugate Filaments for Chemoimmunotherapy of Triple-Negative Breast Cancer
期刊论文
OAI收割
ADVANCED MATERIALS, 2023, 页码: 12
作者:
Cai, Ying
;
Zhu, Binyu
;
Shan, Xiaoting
;
Zhou, Lingli
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/01/16
Fas ligand
immunotherapy
peptide-drug conjugate
triple-negative breast cancer
tumor-associated endothelial cells
The anticancer potential of chemical constituents of Moringa oleifera targeting CDK-2 inhibition in estrogen receptor positive breast cancer using in-silico and in vitro approches
期刊论文
OAI收割
BMC COMPLEMENTARY MEDICINE AND THERAPIES, 2023, 卷号: 23, 期号: 1, 页码: 17
作者:
Sultan, Rida
;
Ahmed, Abrar
;
Wei, Li
;
Saeed, Hamid
;
Islam, Muhammad
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/19
CDK2
ER+ Breast cancer
Molecular Docking
MM-GBSA
Molecular Dynamic Simulations
MTT assay
Moringa oleifera
Phytoconstituents
Chlorogenic acid
OTTM: an automated classification tool for translational drug discovery from omics data
期刊论文
OAI收割
BRIEFINGS IN BIOINFORMATICS, 2023, 页码: 12
作者:
Yang, Xiaobo
;
Zhang, Bei
;
Wang, Siqi
;
Lu, Ye
;
Chen, Kaixian
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/10/17
OTTM
omics data
translational drug discovery
literature mining
hepatocellular carcinoma
Adaptive mechanisms of Bacillus to near space extreme environments
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 886, 页码: 14
作者:
Deng, Aihua
;
Wang, Tiantian
;
Wang, Junyue
;
Li, Lai
;
Wang, Xueliang
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/01/02
Near space
Bacillus
Genome
Transcriptome
Proteome
Adaptive mechanism