中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [15]
中国科学院大学 [4]
海洋研究所 [4]
上海生物化学与细胞生... [4]
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N-degron-mediated degradation of the proteolytically activated form of PKC-theta kinase attenuates its pro-apoptotic function
期刊论文
OAI收割
CELLULAR SIGNALLING, 2023, 卷号: 110
作者:
Eldeeb, Mohamed A.
;
Zhou, Wenbin
;
Esmaili, Mansoore
;
Elgohary, Alaa M.
;
Wei, Hai
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/01
Matrix Thermal Shift Assay for Fast Construction of Multidimensional Ligand-Target Space
期刊论文
OAI收割
ANALYTICAL CHEMISTRY, 2022, 卷号: 94, 期号: 17, 页码: 6482-6490
作者:
Ruan, Chengfei
;
Wang, Yan
;
Zhang, Xiaolei
;
Lyu, Jiawen
;
Zhang, Na
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2022/11/08
DRUG
STABILIZATION
IRON
CUL5-SOCS6 complex regulates mTORC2 function by targeting Sin1 for degradation
期刊论文
OAI收割
CELL DISCOVERY, 2019, 卷号: 5, 期号: -, 页码: 52
作者:
Cui, Binghai
;
Gong, Liyan
;
Chen, Min
;
Zhang, Yuxue
;
Gao, Daming
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/12/09
Hepatocellular carcinoma
Oxidative stress
Cardiolipin
4-hydroxy-2-nonenal
Apoptosis
Staurosporine Derivatives Generated by Pathway Engineering in a Heterologous Host and Their Cytotoxic Selectivity
期刊论文
OAI收割
JOURNAL OF NATURAL PRODUCTS, 2018, 卷号: 81, 期号: 8, 页码: 1745-1751
作者:
Xiao, Fei
;
Li, Huayue
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/08/23
Staurosporine targets the Hippo pathway to inhibit cell growth
期刊论文
OAI收割
JOURNAL OF MOLECULAR CELL BIOLOGY, 2018, 卷号: 10, 期号: 3, 页码: 267-269
作者:
Ma, Xueyan
;
Li, Peixue
;
Li, Jinhui
;
Huang, Hongling
;
Wang, Chao
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/04/28
Organ Size
Yap
Inactivation
Mechanisms
Carcinoma
Oncogene
Anti-proliferation activity of terpenoids isolated from Euphorbia kansui in human cancer cells and their structure-activity relationship
期刊论文
OAI收割
CHINESE JOURNAL OF NATURAL MEDICINES, 2017, 卷号: 15, 期号: 10, 页码: 766-774
作者:
Hou Jin-Jun
;
Shen Yao
;
Yang Zhou
;
Fang Lin
;
Cai Lu-Ying
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
Terpenoids
Anti-proliferation activity
Human cancer cells
Structure-activity relationship
Mitochondrial control of apoptosis through modulation of cardiolipin oxidation in hepatocellular carcinoma: A novel link between oxidative stress and cancer
期刊论文
OAI收割
FREE RADICAL BIOLOGY AND MEDICINE, 2017, 卷号: 102, 期号: -, 页码: 67-76
作者:
Zhong, Huiqin
;
Xiao, Mengqing
;
Zhu, Mingjiang
;
Sa, Rina
;
Lu, Jianhong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/12/09
Hepatocellular carcinoma
Oxidative stress
Cardiolipin
4-hydroxy-2-nonenal
Apoptosis
Staurosporine as an agonist for induction of GLUT4 translocation, identified by a pH-sensitive fluorescent IRAP-mOrange2 probe
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2016, 卷号: 480, 期号: 4, 页码: 534-538
作者:
Li, Yufeng
;
Zheng, Li
;
Wang, Dan
;
Zhang, Xiang
;
Li, Jia
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Diabetes
pH-sensitive fluorescent probe
GLUT4 translocation
Staurosporine
Insulin additive analogue
MG132, a proteasome inhibitor, enhances LDL uptake in HepG2 cells in vitro by regulating LDLR and PCSK9 expression
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 8, 页码: 994-1004
作者:
Yan, Hong
;
Ma, Yan-ling
;
Gui, Yu-zhou
;
Wang, Shu-mei
;
Wang, Xin-bo
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
cholesterol homeostasis
LDLR
MG132
proteasome inhibition
PKC
PCSK9
pravastatin
HepG2
cells
Cloning, Characterization and Heterologous Expression of the Indolocarbazole Biosynthetic Gene Cluster from Marine-Derived Streptomyces sanyensis FMA
期刊论文
OAI收割
MARINE DRUGS, 2013, 卷号: 11, 期号: 2, 页码: 466-488
作者:
Li, Tong
;
Du, Yuanyuan
;
Cui, Qiu
;
Zhang, Jingtao
;
Zhu, Weiming
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2015/11/02
indolocarbazole (ICZ)
biosynthesis
heterologous expression
Streptomyces sanyensis FMA