中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [16]
西北高原生物研究所 [11]
大连化学物理研究所 [8]
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期刊论文 [80]
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Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 22
作者:
Guma, Samuel Desta
;
Zhou, Zhaoyin
;
Song, Kang
;
Yang, Feipu
;
Suo, Jin
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/12/11
SARS-CoV-2
3CL pro inhibitors
Peptidomimetics
Spiropyrrolidine derivatives
F-CPI: A Multimodal Deep Learning Approach for Predicting Compound Bioactivity Changes Induced by Fluorine Substitution
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 13
作者:
Zhang, Qian
;
Yin, Wenhai
;
Chen, Xinyao
;
Zhou, Aimin
;
Zhang, Guixu
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/02/28
Discovery of Novel SIRT1/2 Inhibitors with Effective Cytotoxicity against Human Leukemia Cells
期刊论文
OAI收割
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2023, 页码: 11
作者:
Cai, Haiyan
;
Wang, Yingying
;
Zhang, Jing
;
Wei, Zhenquan
;
Yan, Teng
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2023/10/17
Development of a multiple convolutional neural network-facilitated diagnostic screening program for immunofluorescence images of IgA nephropathy and idiopathic membranous nephropathy
期刊论文
OAI收割
CLINICAL KIDNEY JOURNAL, 2023, 页码: 11
作者:
Xia, Peng
;
Lv, Zhilong
;
Wen, Yubing
;
Zhang, Baichuan
;
Zhao, Xuesong
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/12/04
convolutional neural network
idiopathic membranous nephropathy
IgA nephropathy
immunofluorescence
Histopathological bladder cancer gene mutation prediction with hierarchical deep multiple-instance learning
期刊论文
OAI收割
MEDICAL IMAGE ANALYSIS, 2023, 卷号: 87, 页码: 13
作者:
Yan, Rui
;
Shen, Yijun
;
Zhang, Xueyuan
;
Xu, Peihang
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/12/04
Bladder cancer
Contrastive learning
Gene mutation prediction
Histopathological image analysis
Multiple instance learning
DCZ19931, a novel multi-targeting kinase inhibitor, inhibits ocular neovascularization
期刊论文
OAI收割
SCIENTIFIC REPORTS, 2022, 卷号: 12, 期号: 1, 页码: 15
作者:
Zhang, Huiying
;
Li, Bo
;
Ding, Jingjuan
;
Ye, Rong
;
Xu, Zhijian
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2023/10/17
Disruption of C/EBP beta-Clec7a axis exacerbates neuroinflammatory injury via NLRP3 inflammasome-mediated pyroptosis in experimental neuropathic pain
期刊论文
OAI收割
JOURNAL OF TRANSLATIONAL MEDICINE, 2022, 卷号: 20, 期号: 1, 页码: 19
作者:
Wu, Dan
;
Zhang, Yanqiong
;
Zhao, Chunhui
;
Li, Qiuyue
;
Zhang, Junhong
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2023/04/10
C/EBP beta-Clec7a axis
Neuroinflammation
Neuropathic Pain
NLRP3 Inflammasome-mediated Pyroptosis
Suppression of Pathological Ocular Neovascularization by a Small Molecular Multi-Targeting Kinase Inhibitor, DCZ19903
期刊论文
OAI收割
TRANSLATIONAL VISION SCIENCE & TECHNOLOGY, 2022, 卷号: 11, 期号: 12, 页码: 15
作者:
Ding, Jingjuan
;
Li, Bo
;
Zhang, Huiying
;
Xu, Zhijian
;
Zhang, Qiuyang
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/10/17
ocular neovascularization
DCZ19903
multitarget kinase inhibitor
network pharmacology
MAPK signaling pathway
JUNO physics and detector
期刊论文
OAI收割
PROGRESS IN PARTICLE AND NUCLEAR PHYSICS, 2022, 卷号: 123, 页码: 51
作者:
Abusleme, Angel
  |  
收藏
  |  
浏览/下载:134/0
  |  
提交时间:2022/04/11
JUNO
neutrino physics
neutrino detector
CoVac501, a self-adjuvanting peptide vaccine conjugated with TLR7 agonists, against SARS-CoV-2 induces protective immunity
期刊论文
OAI收割
CELL DISCOVERY, 2022, 卷号: 8, 期号: 1, 页码: 16
作者:
Long, Yiru
;
Sun, Jianhua
;
Song, Tian-Zhang
;
Liu, Tingting
;
Tang, Feng
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2022/06/15