机构

• 上海药物研究所 [18]
• 西北高原生物研究所 [11]
• 大连化学物理研究所 [8]
• 近代物理研究所 [7]
• 青海盐湖研究所 [6]
• 深圳先进技术研究院 [4]
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• iSwitch采集 [2]

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• 期刊论文 [82]
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• 学位论文 [1]

发表日期

• 2025 [3]
• 2023 [3]
• 2022 [6]
• 2021 [10]
• 2020 [1]
• 2019 [4]
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学科主题

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浏览/检索结果: 共88条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 Discovery of multi-chitinase inhibitors cinnamyl thiazolidinone compounds as candidates for insect growth regulators via ligand-based optimization strategies 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 卷号: 306, 页码: 14 作者:  Jiang, Zhiyang;  Shi, Dongmei;  Fu, Haoyu;  Li, Yan;  Zou, Renxuan   |  收藏  |  浏览/下载：3/0  |  提交时间：2025/05/27 Multi-chitinase inhibitor  Cinnamaldehyde compounds  Thiazolidinone compounds  Ligand-based optimization  Insect growth regulators (IGRs)   Design, Synthesis, and Biological Evaluation of Peptidomimetic Tetrahydropyrrole Spirodihydroindolones as SARS-CoV-2 3CL Protease Inhibitors 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 16, 期号: 5, 页码: 790-796 作者:  Hu, Liuyan;  Zhao, Zhi;  Zhang, Shujing;  Yang, Lei;  Cui, Wenjie   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/06/23 COVID-19  SARS-CoV-2  3CL protease  Peptidomimetic inhibitors  Tetrahydropyrrole spirodihydroindolone   Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 22 作者:  Guma, Samuel Desta;  Zhou, Zhaoyin;  Song, Kang;  Yang, Feipu;  Suo, Jin   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/12/11 SARS-CoV-2  3CL pro inhibitors  Peptidomimetics  Spiropyrrolidine derivatives   F-CPI: A Multimodal Deep Learning Approach for Predicting Compound Bioactivity Changes Induced by Fluorine Substitution 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 13 作者:  Zhang, Qian;  Yin, Wenhai;  Chen, Xinyao;  Zhou, Aimin;  Zhang, Guixu   |  收藏  |  浏览/下载：16/0  |  提交时间：2025/02/28 Discovery of Novel SIRT1/2 Inhibitors with Effective Cytotoxicity against Human Leukemia Cells 期刊论文  OAI收割 JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2023, 页码: 11 作者:  Cai, Haiyan;  Wang, Yingying;  Zhang, Jing;  Wei, Zhenquan;  Yan, Teng   |  收藏  |  浏览/下载：34/0  |  提交时间：2023/10/17 Development of a multiple convolutional neural network-facilitated diagnostic screening program for immunofluorescence images of IgA nephropathy and idiopathic membranous nephropathy 期刊论文  OAI收割 CLINICAL KIDNEY JOURNAL, 2023, 页码: 11 作者:  Xia, Peng;  Lv, Zhilong;  Wen, Yubing;  Zhang, Baichuan;  Zhao, Xuesong   |  收藏  |  浏览/下载：28/0  |  提交时间：2023/12/04 convolutional neural network  idiopathic membranous nephropathy  IgA nephropathy  immunofluorescence   Histopathological bladder cancer gene mutation prediction with hierarchical deep multiple-instance learning 期刊论文  OAI收割 MEDICAL IMAGE ANALYSIS, 2023, 卷号: 87, 页码: 13 作者:  Yan, Rui;  Shen, Yijun;  Zhang, Xueyuan;  Xu, Peihang;  Wang, Jun   |  收藏  |  浏览/下载：28/0  |  提交时间：2023/12/04 Bladder cancer  Contrastive learning  Gene mutation prediction  Histopathological image analysis  Multiple instance learning   DCZ19931, a novel multi-targeting kinase inhibitor, inhibits ocular neovascularization 期刊论文  OAI收割 SCIENTIFIC REPORTS, 2022, 卷号: 12, 期号: 1, 页码: 15 作者:  Zhang, Huiying;  Li, Bo;  Ding, Jingjuan;  Ye, Rong;  Xu, Zhijian   |  收藏  |  浏览/下载：39/0  |  提交时间：2023/10/17 Disruption of C/EBP beta-Clec7a axis exacerbates neuroinflammatory injury via NLRP3 inflammasome-mediated pyroptosis in experimental neuropathic pain 期刊论文  OAI收割 JOURNAL OF TRANSLATIONAL MEDICINE, 2022, 卷号: 20, 期号: 1, 页码: 19 作者:  Wu, Dan;  Zhang, Yanqiong;  Zhao, Chunhui;  Li, Qiuyue;  Zhang, Junhong   |  收藏  |  浏览/下载：35/0  |  提交时间：2023/04/10 C/EBP beta-Clec7a axis  Neuroinflammation  Neuropathic Pain  NLRP3 Inflammasome-mediated Pyroptosis   Suppression of Pathological Ocular Neovascularization by a Small Molecular Multi-Targeting Kinase Inhibitor, DCZ19903 期刊论文  OAI收割 TRANSLATIONAL VISION SCIENCE & TECHNOLOGY, 2022, 卷号: 11, 期号: 12, 页码: 15 作者:  Ding, Jingjuan;  Li, Bo;  Zhang, Huiying;  Xu, Zhijian;  Zhang, Qiuyang   |  收藏  |  浏览/下载：20/0  |  提交时间：2023/10/17 ocular neovascularization  DCZ19903  multitarget kinase inhibitor  network pharmacology  MAPK signaling pathway