中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [29]
广州能源研究所 [7]
金属研究所 [4]
地理科学与资源研究所 [4]
烟台海岸带研究所 [3]
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OAI收割 [59]
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期刊论文 [59]
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GENNDTI: Drug-Target Interaction Prediction Using Graph Neural Network Enhanced by Router Nodes
期刊论文
OAI收割
IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS, 2024, 卷号: 28, 期号: 12, 页码: 7588-7598
作者:
Yang, Beiyuan
;
Liu, Yule
;
Wu, Junfeng
;
Bai, Fang
;
Zheng, Mingyue
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/01/14
DTI
interpretability
graph enhancement
prior knowledge
graph neural network
DTI
interpretability
graph enhancement
prior knowledge
graph neural network
miCGR: interpretable deep neural network for predicting both site-level and gene-level functional targets of microRNA
期刊论文
OAI收割
BRIEFINGS IN BIOINFORMATICS, 2024, 卷号: 26, 期号: 1, 页码: 13
作者:
Wu, Xiaolong
;
Zhang, Lehan
;
Tong, Xiaochu
;
Wang, Yitian
;
Zhang, Zimei
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/12/25
MicroRNA
target prediction
chaos game representation
deep learning
convolutional neural network
Covalent DNA-Encoded Library Workflow Drives Discovery of SARS-CoV-2 Nonstructural Protein Inhibitors
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2024, 页码: 14
作者:
Wang, Xudong
;
Xiong, Liwei
;
Zhu, Ying
;
Liu, Sixiu
;
Zhao, Wenfeng
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/12/25
Ginkgetin Alleviates Inflammation and Senescence by Targeting STING
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 15
作者:
Liu, Yadan
;
Ye, Jialin
;
Fan, Zisheng
;
Wu, Xiaolong
;
Zhang, Yinghui
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/12/16
cGAS-STING signaling
Ginkgetin
senescence
STING inhibitor
target identification
Enhancing the Predictive Power of Machine Learning Models through a Chemical Space Complementary DEL Screening Strategy
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 12
作者:
Suo, Yanrui
;
Qian, Xu
;
Xiong, Zhaoping
;
Liu, Xiaohong
;
Wang, Chao
  |  
收藏
  |  
浏览/下载:91/0
  |  
提交时间:2024/11/26
Amelioration of nonalcoholic fatty liver disease by inhibiting the deubiquitylating enzyme RPN11
期刊论文
OAI收割
CELL METABOLISM, 2024, 卷号: 36, 期号: 10, 页码: 25
作者:
Zhou, Bing
;
Luo, Yunchen
;
Bi, Hanqi
;
Zhang, Ni
;
Ma, Mingyue
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/11/26
Siteselective and Enantiocomplementary C(sp
3
)-H Oxyfunctionalization for Synthesis of α-Hydroxy Acids
期刊论文
OAI收割
ACS CATALYSIS, 2024, 卷号: 14, 期号: 7, 页码: 4463-4470
作者:
Lian, Xin
;
Mao, Yingle
;
Fu, Zunyun
;
Zhang, Weijie
;
Chen, Jiayan
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/05/07
biocatalysis
C(sp(3))-H functionalization
dioxygenases
asymmetric synthesis
alpha-hydroxyacids
Targeting JMJD1C to selectively disrupt tumor T
reg
cell fitness enhances antitumor immunity
期刊论文
OAI收割
NATURE IMMUNOLOGY, 2024, 页码: 32
作者:
Long, Xuehui
;
Zhang, Sulin
;
Wang, Yuliang
;
Chen, Jingjing
;
Lu, Yanlai
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2024/03/25
Versatile Biocatalytic C(sp(3))-H Oxyfunctionalization for the Site- Selective and Stereodivergent Synthesis of & alpha;- and & beta;-Hydroxy Acids
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023, 页码: 9
作者:
Mao, Yingle
;
Zhang, Weijie
;
Fu, Zunyun
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2023/10/17
Asymmetric Synthesis
Biocatalysis
C(sp(3))-H Functionalization
Dioxygenases
Enzymes
Erosion Performance of TiAlSiN Coatings Prepared by High-Power Pulsed Magnetron Sputtering
期刊论文
OAI收割
METALS, 2023, 卷号: 13, 期号: 7, 页码: 1306
作者:
Li, Hua
;
Li, Liuhe
;
Li, Duoduo
;
Tang, Ling
;
Luo, Yang
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2023/09/05
erosion resistance
phase composition
TiAlSiN coating
discharge voltages