中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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高能物理研究所 [65]
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期刊论文 [223]
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Design, synthesis and biological evaluation of Alisol B derivatives for potential treatment of non-alcoholic steatohepatitis
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 155, 页码: 15
作者:
Yu, Nai-Rong
;
Huang, Suling
;
Deng, Zhen-Tao
;
Wang, Jiayue
;
Shen, Yu
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/04/01
Non-alcoholic steatohepatitis (NASH)
Alisol B
Structural modification
Structure-activity relationship
HFD+CCl4-induced NASH mice model
A new mechanism of thyroid hormone receptor β agonists ameliorating nonalcoholic steatohepatitis by inhibiting intestinal lipid absorption via remodeling bile acid profiles
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 15
作者:
Sun, Kai
;
Zhu, Nan-lin
;
Huang, Su-ling
;
Qu, Hui
;
Gu, Yi-pei
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/07/12
nonalcoholic steatohepatitis
THR beta agonists
resmetirom
bile acids composition
intestinal lipid absorption
First Asian fossil record of Platydictya (Amblystegiaceae) from the lower Miocene and its paleoenvironmental significance
期刊论文
OAI收割
FRONTIERS OF EARTH SCIENCE, 2023, 页码: 10
作者:
Guo, Liyan
;
Xiao, Liang
;
Li, Ya
;
Li, Xiangchuan
;
Leng, Qin
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/09
moss
the Pingzhuang Coal Mine
Inner Mongolia
Platydictya
paleoenvironment
Phenotypic screening-based drug discovery of furan-2-carboxylic acid derivatives for the amelioration of type 2 diabetes mellitus (T2DM)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 246, 页码: 11
作者:
Chen, Lili
;
Huang, Suling
;
Ye, Yangliang
;
Shen, Yu
;
Xu, Tifei
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2023/04/10
Phenotypic screening
Gluconeogenesis
Furan-2-carboxylic acid
T2DM
Development and structure–activity relationships of tanshinones as selective 11β-hydroxysteroid dehydrogenase 1 inhibitors
期刊论文
OAI收割
Natural Products and Bioprospecting, 2022, 卷号: 12, 期号: 1
作者:
Deng,Xu
;
Huang,Su-Ling
;
Ren,Jian
;
Pan,Zheng-Hong
;
Shen,Yu
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/11/11
Metabolic syndrome
Tanshinones
Selective 11β-HSD1 inhibitors
Structure–activity relationships
Development and structure-activity relationships of tanshinones as selective 11beta-hydroxysteroid dehydrogenase 1 inhibitors
期刊论文
OAI收割
Natural products and bioprospecting, 2022, 卷号: 12, 期号: 1, 页码: 36
作者:
Deng, Xu
;
Huang, Su-Ling
;
Ren, Jian
;
Pan, Zheng-Hong
;
Shen, Yu
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/03/15
Metabolic syndrome
Selective 11beta-HSD1 inhibitors
Structure-activity relationships
Tanshinones
Alisol B Alleviates Hepatocyte Lipid Accumulation and Lipotoxicity via Regulating RAR alpha-PPAR gamma-CD36 Cascade and Attenuates Non-Alcoholic Steatohepatitis in Mice
期刊论文
OAI收割
NUTRIENTS, 2022, 卷号: 14, 期号: 12, 页码: 20
作者:
Zhao, Zhuohui
;
Deng, Zhen-Tao
;
Huang, Suling
;
Ning, Mengmeng
;
Feng, Ying
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/08/16
Alisol B
non-alcoholic steatohepatitis
RAR alpha
CD36
Design, synthesis and structural-activity relationship studies of phanginin A derivatives for regulating SIK1-cAMP/CREB signaling to suppress hepatic gluconeogenesis
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 232, 页码: 14
作者:
Wu, Xing-De
;
Huang, Suling
;
Shi, Yu
;
Shen, Yu
;
Tu, Wen-Chao
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/08/16
Hepatic gluconeogenesis
Type 2 diabetes
Phanginin A derivatives
SIK1
Structural-activity relationship
High zero-bias responsivity induced by photogating effect in asymmetric device structure
期刊论文
OAI收割
OPTICAL MATERIALS, 2022, 卷号: 124, 页码: 7
作者:
Gao, Kaicong
;
Ran, Shuling
;
Han, Qin
;
Yang, Qi
;
Jiang, Hao
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2022/08/22
Graphene photodetector
CdS thin films
Asymmetric structure
Constraining conifer physiological parameters in leaf gas-exchange models for ancient CO2 reconstruction
期刊论文
OAI收割
GLOBAL AND PLANETARY CHANGE, 2022, 卷号: 209, 期号: _, 页码: -
作者:
Liang, Jia-Qi
;
Leng, Qin
;
Hofig, Daianne F.
;
Niu, Gao
;
Wang, Li
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/04/25
Franks model
CO2 reconstruction
Stomatal parameters
Bulk-leaf delta C-13
Natural variations
Conifer fossils