中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [18]
大连化学物理研究所 [1]
昆明植物研究所 [1]
过程工程研究所 [1]
自动化研究所 [1]
昆明动物研究所 [1]
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OAI收割 [23]
内容类型
期刊论文 [23]
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2023 [1]
2022 [3]
2021 [5]
2020 [3]
2019 [3]
2018 [2]
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学科主题
Endocrinol... [1]
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Phenotypic screening-based drug discovery of furan-2-carboxylic acid derivatives for the amelioration of type 2 diabetes mellitus (T2DM)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 246, 页码: 11
作者:
Chen, Lili
;
Huang, Suling
;
Ye, Yangliang
;
Shen, Yu
;
Xu, Tifei
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/04/10
Phenotypic screening
Gluconeogenesis
Furan-2-carboxylic acid
T2DM
Alisol B Alleviates Hepatocyte Lipid Accumulation and Lipotoxicity via Regulating RAR alpha-PPAR gamma-CD36 Cascade and Attenuates Non-Alcoholic Steatohepatitis in Mice
期刊论文
OAI收割
NUTRIENTS, 2022, 卷号: 14, 期号: 12, 页码: 20
作者:
Zhao, Zhuohui
;
Deng, Zhen-Tao
;
Huang, Suling
;
Ning, Mengmeng
;
Feng, Ying
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/08/16
Alisol B
non-alcoholic steatohepatitis
RAR alpha
CD36
Design, synthesis and structural-activity relationship studies of phanginin A derivatives for regulating SIK1-cAMP/CREB signaling to suppress hepatic gluconeogenesis
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 232, 页码: 14
作者:
Wu, Xing-De
;
Huang, Suling
;
Shi, Yu
;
Shen, Yu
;
Tu, Wen-Chao
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/08/16
Hepatic gluconeogenesis
Type 2 diabetes
Phanginin A derivatives
SIK1
Structural-activity relationship
Development and structure-activity relationships of tanshinones as selective 11β-hydroxysteroid dehydrogenase 1 inhibitors
期刊论文
OAI收割
NATURAL PRODUCTS AND BIOPROSPECTING, 2022, 卷号: 12, 期号: 6, 页码: 1
作者:
Deng Xu
;
Huang Suling
;
Ren Jian
;
Pan Zhenghong
;
Shen Yu
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/05/22
Metabolic syndrome
Tanshinones
Selective 11β-HSD1 inhibitors
Structure-activity relationships
Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK
期刊论文
OAI收割
CLINICAL SCIENCE, 2021, 卷号: 135, 期号: 19, 页码: 2243-2263
作者:
Elksnis, Andris
;
Schiffer, Tomas A.
;
Palm, Fredrik
;
Wang, Yun
;
Cen, Jing
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/12/01
A new mechanism of obeticholic acid on NASH treatment by inhibiting NLRP3 inflammasome activation in macrophage
期刊论文
OAI收割
METABOLISM-CLINICAL AND EXPERIMENTAL, 2021, 卷号: 120, 页码: 12
作者:
Huang, Suling
;
Wu, Yanwei
;
Zhao, Zhuohui
;
Wu, Bing
;
Sun, Kai
  |  
收藏
  |  
浏览/下载:107/0
  |  
提交时间:2021/08/17
Macrophage
NLRP3 inflammasome
Hepatic lipid accumulation
NASH
FXR
Multicolor Coding Up-Conversion Nanoplatform for Rapid Screening of Multiple Foodborne Pathogens
期刊论文
OAI收割
ACS APPLIED MATERIALS & INTERFACES, 2021, 卷号: 13, 期号: 23, 页码: 26782-26789
作者:
Hu, Qiushi
;
Wu, Qixiao
;
Huang, Fengchun
;
Xu, Zheng
;
Zhou, Lei
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2021/08/31
multicolor coding
up-conversion nanoparticles
photoluminescence
multiplex detection
foodborne pathogen
Metabolomic Study of High-Fat Diet-Induced Obese (DIO) and DIO Plus CCl4-Induced NASH Mice and the Effect of Obeticholic Acid
期刊论文
OAI收割
METABOLITES, 2021, 卷号: 11, 期号: 6, 页码: 374
作者:
Zhu, Nanlin
;
Huang, Suling
;
Zhang, Qingli
;
Zhao, Zhuohui
;
Qu, Hui
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/03/21
nonalcoholic fatty liver disease (NAFLD)
nonalcoholic fatty liver (NAFL)
nonalcoholic steatohepatitis (NASH)
differential metabolites
metabolic pathways
obeticholic acid (OCA)
An integrative drug repositioning framework discovered a potential therapeutic agent targeting COVID-19
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 16
作者:
Ge, Yiyue
;
Tian, Tingzhong
;
Huang, Suling
;
Wan, Fangping
;
Li, Jingxin
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/06/15
Activation of SIK1 by phanginin A inhibits hepatic gluconeogenesis by increasing PDE4 activity and suppressing the cAMP signaling pathway
期刊论文
OAI收割
MOLECULAR METABOLISM, 2020, 卷号: 41, 页码: 15
作者:
Liu, Siwen
;
Huang, Suling
;
Wu, Xingde
;
Feng, Ying
;
Shen, Yu
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/12/24
Salt-inducible kinase 1
Phanginin A
Phosphodiesterase 4
Gluconeogenesis
cAMP