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浏览/检索结果: 共57条，第1-10条 帮助

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Optimization and Biological Evaluation of Novel 1H-Pyrrolo[2,3-c]pyridin Derivatives as Potent and Reversible Lysine Specific Demethylase 1 Inhibitors for the Treatment of Acute Myelogenous Leukemia 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 24, 页码: 22080-22103
作者:  Jiang, Hong;  Li, Cong;  Li, Na;  Sheng, Li;  Wang, Jingkai
  |  收藏  |  浏览/下载：6/0  |  提交时间：2025/01/14
Structural Basis of Main Proteases of Coronavirus Bound to Bofutrelvir 期刊论文  OAI收割
JOURNAL OF MOLECULAR BIOLOGY, 2024, 卷号: 436, 期号: 22, 页码: 16
作者:  Wang, Wei-wei;  Zeng, Pei;  Liu, Tongchao;  Zhou, Xue-lan;  Lin, Cheng
  |  收藏  |  浏览/下载：12/0  |  提交时间：2024/10/21
Design, synthesis, and biological evaluation of pyrido[2,3-d]pyrimidin-7 (8H)-one derivatives as potent USP1 inhibitors 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 275, 页码: 18
作者:  Li, Hongrui;  Liu, Ben-Jin;  Xu, Jiahao;  Song, Shan-Shan;  Ba, Ruixian
  |  收藏  |  浏览/下载：8/0  |  提交时间：2024/08/22
Structure-based discovery of a new series of nucleoside-derived ring-opening PRMT5 inhibitors 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 267, 页码: 19
作者:  Chen, Yuting;  Wang, Zekun;  Zhang, Junjie;  Shi, Qiongyu;  Yang, Hong
  |  收藏  |  浏览/下载：10/0  |  提交时间：2024/05/07
Design and synthesis of 1H-pyrazolo[3,4-d]pyrimidine derivatives as hematopoietic progenitor kinase 1 (HPK1) inhibitors 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 140, 页码: 18
作者:  Zhang, Junjie;  Li, Yan;  Tang, Haotian;  Zhou, Qianqian;  Tong, Linjiang
  |  收藏  |  浏览/下载：21/0  |  提交时间：2023/12/08
Structure-based discovery of potent USP28 inhibitors derived from Vismodegib 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 15
作者:  Zhou, Di;  Xu, Zhuo;  Huang, Yaodong;  Wang, Hui;  Zhu, Xiaoli
  |  收藏  |  浏览/下载：39/0  |  提交时间：2023/10/17
Development of a series of quinazoline-2,5-diamine derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 248, 页码: 20
作者:  Shi, Huanyu;  Tang, Haotian;  Li, Yan;  Chen, Danqi;  Liu, Tongchao
  |  收藏  |  浏览/下载：30/0  |  提交时间：2023/04/10
Structure-activity relationship study of a series of nucleoside derivatives bearing sulfonamide scaffold as potent and selective PRMT5 inhibitors 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 130, 页码: 20
作者:  Chen, Yuting;  Shi, Qiongyu;  Yang, Hong;  Li, Jiayi;  Zhou, Kaixin
  |  收藏  |  浏览/下载：33/0  |  提交时间：2023/04/10
Identification of 1H-pyrazolo[3,4-b]pyridine derivatives as novel and potent TBK1 inhibitors: design, synthesis, biological evaluation, and molecular docking study 期刊论文  OAI收割
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1411-1425
作者:  Sun, Yin;  Tang, Haotian;  Wang, Xiaoyan;  Feng, Fang;  Fan, Tiantian
  |  收藏  |  浏览/下载：49/0  |  提交时间：2022/08/16
Discovery of Novel N-(5-(Pyridin-3-yl)-1H-indazol-3-yl)benzamide Derivatives as Potent Cyclin-Dependent Kinase 7 Inhibitors for the Treatment of Autosomal Dominant Polycystic Kidney Disease 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 19
作者:  Yang, Bowen;  Zhang, Haoran;  Li, Na;  Gao, Lixin;  Jiang, Hong
  |  收藏  |  浏览/下载：32/0  |  提交时间：2023/04/10