中国科学院机构知识库网格系统: 检索

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	Discovery of a New-Generation S-Adenosylmethionine-Noncompetitive Covalent Inhibitor Targeting the Lysine Methyltransferase Enhancer of Zeste Homologue 2 期刊论文 OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 11, 页码: 7629-7644 作者: Zhang, Yi; Yang, Hong; Li, Bingbing; Li, Jiayi; Li, Huaxuan \| 收藏 \| 浏览/下载：20/0 \| 提交时间：2023/10/17
	Structural Modification and Pharmacological Evaluation of Substituted Quinoline-5,8-diones as Potent NSD2 Inhibitors 期刊论文 OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 18 作者: Tang, Hairong; Yu, Aisong; Xing, Li; Chen, Xiaoyu; Ding, Huaqian \| 收藏 \| 浏览/下载：16/0 \| 提交时间：2023/04/10
	Structure-activity relationship study of a series of nucleoside derivatives bearing sulfonamide scaffold as potent and selective PRMT5 inhibitors 期刊论文 OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 130, 页码: 20 作者: Chen, Yuting; Shi, Qiongyu; Yang, Hong; Li, Jiayi; Zhou, Kaixin \| 收藏 \| 浏览/下载：20/0 \| 提交时间：2023/04/10 Epigenetic PRMT5 inhibitor Nucleoside derivatives Structure-activity Relationship Prodrug
	Discovery of a potent and selective proteolysis targeting chimera (PROTAC) degrader of NSD3 histone methyltransferase 期刊论文 OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 239, 页码: 18 作者: Sun, Yaoliang; Zhang, Ying; Chen, Xiaoai; Yu, Aisong; Du, Wenhao \| 收藏 \| 浏览/下载：41/0 \| 提交时间：2022/08/30 NSD3 PROTAC Degrader Methyltransferase
	Discovery of novel benzimidazole derivatives as potent p300 bromodomain inhibitors with anti-proliferative activity in multiple cancer cells 期刊论文 OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 66, 页码: 16 作者: Chen, Zonglong; Li, Jiayi; Yang, Hong; He, Yulong \| 收藏 \| 浏览/下载：35/0 \| 提交时间：2022/08/16 P300 Bromodomain inhibitors CBP30 SBDD
	Design, synthesis and biological evaluation of (R)-5-methylpyrrolidin-2-ones as p300 bromodomain inhibitors with Anti-Tumor activities in multiple tumor lines 期刊论文 OAI收割 BIOORGANIC CHEMISTRY, 2022, 卷号: 124, 页码: 15 作者: Liu, Ruiqi; Yang, Hong; Chen, Zonglong; Zhou, Kaixin; Shi, Qiongyu \| 收藏 \| 浏览/下载：37/0 \| 提交时间：2022/08/16 Epigenetics p300 CBP Bromodomain inhibitors CCS1477
	Structure-Aided Design, Synthesis, and Biological Evaluation of Potent and Selective Non-Nucleoside Inhibitors Targeting Protein Arginine Methyltransferase 5 期刊论文 OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 11, 页码: 7854-7875 作者: Rong, Deqin; Zhou, Kaixin; Fang, Wei; Yang, Hong; Zhang, Yi \| 收藏 \| 浏览/下载：26/0 \| 提交时间：2022/08/16
	Structure-Based Discovery of Potent CARM1 Inhibitors for Solid Tumor and Cancer Immunology Therapy 期刊论文 OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 22, 页码: 16650-16674 作者: Zhang, Zhuqing; Guo, Zuhao; Xu, Xiaowei; Cao, Danyan; Yang, Hong \| 收藏 \| 浏览/下载：25/0 \| 提交时间：2022/06/15
	5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma 期刊论文 OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19 作者: Wang, Shuni; Yang, Hong; Su, Mingbo; Lian, Fulin; Cong, Zhanqing \| 收藏 \| 浏览/下载：64/0 \| 提交时间：2021/11/04 NSD2 Methyltransferase HTS Multiple myeloma 5-Aminonaphthalene derivatives Inhibitor