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浏览/检索结果: 共102条，第1-10条 帮助

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Structure-activity relationship analysis of meta-substituted N-cyclopropylmethyl-nornepenthones with mixed KOR/MOR activities 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 289, 页码: 15
作者:  Tang, Siyuan;  Hu, Shuyang;  Feng, Lijing;  Kong, Linghui;  Gui, Jiangwen
  |  收藏  |  浏览/下载：4/0  |  提交时间：2025/05/27
Discovery of an Ortho-Substituted N-Cyclopropylmethyl-7α-phenyl-6,14-endoethano-tetrahydronorthebaine Derivative as a Selective and Potent Kappa Opioid Receptor Agonist with Subsided Sedative Effect 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 9, 页码: 7112-7129
作者:  Li, Zixiang;  Ye, Rufeng;  He, Qian;  Lu, Jiashuo;  Sun, Yanting
  |  收藏  |  浏览/下载：32/0  |  提交时间：2024/06/27
Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 15
作者:  Kong, Linghui;  Ning, Kuan;  Liu, Xiao;  Lu, Jiashuo;  Chen, Baiyu
  |  收藏  |  浏览/下载：44/0  |  提交时间：2023/10/17
SLL-627 Is a Highly Selective and Potent ? Opioid Receptor (KOR) Agonist with an Unexpected Nonreduction in Locomotor Activity 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 16
作者:  Kong, Linghui;  Shu, Xuelian;  Tang, Siyuan;  Ye, Rongrong;  Sun, Huijiao
  |  收藏  |  浏览/下载：68/0  |  提交时间：2022/08/30
Discovery of an M-Substituted N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaine as a Selective, Potent, and Orally Active kappa-Opioid Receptor Agonist with an Improved Central Nervous System Safety Profile 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12414-12433
作者:  He, Qian;  Wei, Yuanyuan;  Liu, Xiao;  Ye, Rongrong;  Kong, Linghui
  |  收藏  |  浏览/下载：94/0  |  提交时间：2021/11/04
Discovery, Structure-Activity Relationship, and Mechanistic Studies of 1-((3R,4S)-3-((Dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenyl)piperidin-1-yl)-2-(2,4,5-trifluorophenyl)ethan-1-one as a Novel Potent Analgesic 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 13, 页码: 9458-9483
作者:  Huang, Huoming;  Li, Xueping;  Xie, Peng;  Li, Xinwei;  Xu, XueJun
  |  收藏  |  浏览/下载：54/0  |  提交时间：2021/08/17
MALDI-MS imaging of lipids and small molecules in rat brain tissue based on graphene oxide film pre-coated matrix 期刊论文  OAI收割
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2021, 卷号: 464, 页码: 8
作者:  Xu, Yang;  Deng, Yingzhi;  Ye, Rongrong;  Gong, Can;  Liu, Zhaoxin
  |  收藏  |  浏览/下载：46/0  |  提交时间：2021/06/11
Exploration of the SAR Connection between Morphinan- and Arylacetamide-Based kappa Opioid Receptor (kappa OR) Agonists Using the Strategy of Bridging 期刊论文  OAI收割
ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 6, 页码: 1018-1030
作者:  Liu, Xiao;  Jiang, Shuang;  Kong, Linghui;  Ye, Rongrong;  Xiao, Li
  |  收藏  |  浏览/下载：104/0  |  提交时间：2021/05/24
Discovery of 3-((dimethylamino)methyl)-4-hydroxy-4-(3-methoxypheny1)-N-phenylpiperidine-1-carboxamide as novel potent analgesic 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 189, 页码: 14
作者:  Huang, Huoming;  Wang, Wenli;  Xu, Xuejun;  Zhu, Chen;  Wang, Yujun
  |  收藏  |  浏览/下载：31/0  |  提交时间：2020/07/01
东天山大南湖-头苏泉岛弧带古生代侵入岩浆活动期次及基底性质 期刊论文  OAI收割
西北地质, 2020, 卷号: 53, 期号: 2, 页码: 1-26
作者:  庞博宸;  李秋根;  陈隽璐;  刘树文;  王宗起
  |  收藏  |  浏览/下载：14/0  |  提交时间：2021/10/27