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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
水生生物研究所 [9]
上海药物研究所 [5]
采集方式
OAI收割 [14]
内容类型
期刊论文 [14]
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2023 [1]
2022 [1]
2021 [2]
2019 [1]
2012 [2]
2011 [5]
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学科主题
Ecology; L... [2]
Environmen... [2]
Physical G... [2]
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Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 15
作者:
Kong, Linghui
;
Ning, Kuan
;
Liu, Xiao
;
Lu, Jiashuo
;
Chen, Baiyu
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
N-cyclopropylmethyl nornepenthone derivatives
derivatives
Structure-activity relationship
MOR antagonist
Functional reversal
Reversal of subtype-selectivity
Opioid use disorder
SLL-627 Is a Highly Selective and Potent ? Opioid Receptor (KOR) Agonist with an Unexpected Nonreduction in Locomotor Activity
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 16
作者:
Kong, Linghui
;
Shu, Xuelian
;
Tang, Siyuan
;
Ye, Rongrong
;
Sun, Huijiao
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2022/08/30
Discovery of an M-Substituted N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaine as a Selective, Potent, and Orally Active kappa-Opioid Receptor Agonist with an Improved Central Nervous System Safety Profile
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12414-12433
作者:
He, Qian
;
Wei, Yuanyuan
;
Liu, Xiao
;
Ye, Rongrong
;
Kong, Linghui
  |  
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2021/11/04
Exploration of the SAR Connection between Morphinan- and Arylacetamide-Based kappa Opioid Receptor (kappa OR) Agonists Using the Strategy of Bridging
期刊论文
OAI收割
ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 6, 页码: 1018-1030
作者:
Liu, Xiao
;
Jiang, Shuang
;
Kong, Linghui
;
Ye, Rongrong
;
Xiao, Li
  |  
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2021/05/24
Morphinans
arylacetamidyl substituent
kappa opioid receptor modulators
structure-activity relationships
Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070
作者:
Xiao, Li
;
Wang, Yujun
;
Zhang, Mumei
;
Wu, Weiwei
;
Kong, Linghui
  |  
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2020/07/01
Spatial Distribution of Macroinvertebrate Community along a Longitudinal Gradient in a Eutrophic Reservoir-Bay during Different Impoundment Stages, China
期刊论文
OAI收割
INTERNATIONAL REVIEW OF HYDROBIOLOGY, 2012, 卷号: 97, 期号: 3, 页码: 169-183
作者:
Zhang, Min
;
Cai, Qinghua
;
Xu, Yaoyang
;
Kong, Linghui
;
Tan, Lu
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2012/09/25
Longitudinal Distribution
Zonation
Impoundment
Xiangxi Bay
Three Gorges Reservoir
ZONATION AND ITS INFLUENCING FACTORS OF A LARGE SUBTROPICAL RESERVOIR (DANJIANGKOU RESERVOIR IN CENTRAL CHINA), BASED ON MACROINVERTEBRATES
期刊论文
OAI收割
FRESENIUS ENVIRONMENTAL BULLETIN, 2012, 卷号: 21, 期号: 8, 页码: 2095-2104
作者:
Zhang, Min
;
Cai, Qinghua
;
Xu, Yaoyang
;
Wang, Lan
;
Kong, Linghui
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2013/01/09
Reservoir zonation
macroinvertebrates
RWCS
organic matter
seasonal change
Longitudinal patterns of phytoplankton distribution in a tributary bay under reservoir operation
期刊论文
OAI收割
QUATERNARY INTERNATIONAL, 2011, 卷号: 244, 期号: 2, 页码: 280-288
作者:
Wang, Lan
;
Cai, Qinghua
;
Zhang, Min
;
Tan, Lu
;
Kong, Linghui
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2011/12/22
Multivariate Statistical Techniques
Surface-water Quality
Cluster-analysis
Chlorophyll-a
Secchi-disk
River India
Lake
Clarity
China
Assemblages
Changes in water types under the regulated mode of water level in Three Gorges Reservoir, China
期刊论文
OAI收割
QUATERNARY INTERNATIONAL, 2011, 卷号: 244, 期号: 2, 页码: 272-279
作者:
Xu, Yaoyang
;
Zhang, Min
;
Wang, Lan
;
Kong, Linghui
;
Cai, Qinghua
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2011/12/22
SPRING PHYTOPLANKTON BLOOM
XIANGXI BAY
RESIDENCE TIME
NUTRIENT LIMITATION
3-GORGES RESERVOIR
CHLOROPHYLL-A
ALGAL BLOOMS
EUTROPHICATION
DYNAMICS
MANAGEMENT
Phytoplankton development and ecological status during a cyanobacterial bloom in a tributary bay of the Three Gorges Reservoir, China
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2011, 卷号: 409, 期号: 19, 页码: 3820-3828
作者:
Wang, Lan
;
Cai, Qinghua
;
Tan, Lu
;
Kong, Linghui
;
Cai, QH (reprint author), Chinese Acad Sci, State Key Lab Freshwater Ecol & Biotechnol, Inst Hydrobiol, Wuhan 430072, Peoples R China
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2011/12/22
Cyanobacterial Bloom
Phytoplankton Functional Groups
Longitudinal Pattern
Ecological Status
q Index
Tributary Bay