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浏览/检索结果: 共2676条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序作者升序作者降序题名升序题名降序发表日期升序发表日期降序 Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML) 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17 作者:  Mo, Jun;  Wang, Yuxian;  Pan, Youlu;  Xiao, Qitao;  Zhao, Jinyi   |  收藏  |  浏览/下载：4/0  |  提交时间：2025/08/20 Menin  High binding affinity  Anti-proliferation activity  AML   Discovery of novel imidazo[2,1-b][1,3,4]thiadiazole analogs as fluorescent SHP2 inhibitors 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2025, 卷号: 163, 页码: 10 作者:  Zhang, Chun;  Yan, Xue;  Gao, Li-Xin;  Cao, Zi-Tong;  Cao, Qing   |  收藏  |  浏览/下载：6/0  |  提交时间：2025/08/20 Imidazo[2,1-b][1,3,4]thiadiazole  Inhibitory activities  Fluorescence imaging  Zebrafish  SHP2   The Flat Tail in the Burst Energy Distribution of FRB 20240114A 期刊论文  OAI收割 RESEARCH IN ASTRONOMY AND ASTROPHYSICS, 2025, 卷号: 25, 期号: 8 作者:  Huang YX(黄玉祥);  Zhang, Jun-Shuo;  Xu, Heng;  Hao LF(郝龙飞);  Li KJ(李柯伽)   |  收藏  |  浏览/下载：33/0  |  提交时间：2025/07/14 stars: general  stars: magnetars  radio continuum: stars  stars: neutron   Nonlinear Imaging Detection of Organ Fibrosis in Minute Samples for Early Stage Utilizing Dual-Channel Two-Photon and Second-Harmonic Excitation 期刊论文  OAI收割 BIOSENSORS-BASEL, 2025, 卷号: 15, 期号: 6, 页码: 16 作者:  Yu, Bo-Song;  Cheng, Qing-Di;  Liu, Yi-Zhou;  Zhang, Rui;  Li, Da-Wei   |  收藏  |  浏览/下载：2/0  |  提交时间：2025/08/20 nonlinear imaging  two-photon excitation  second harmonic generation  fibrosis   Organic-Inorganic Fertilization Sustains Crop Yields While Mitigating N2O and NO Emissions in Subtropical Wheat-Maize Systems 期刊论文  OAI收割 AGRICULTURE-BASEL, 2025, 卷号: 15, 期号: 10, 页码: 21 作者:  Liu, Yan;  Hu, Lei;  Zhang, Shihang;  Yao, Zhisheng;  Zhou, Minghua   |  收藏  |  浏览/下载：14/0  |  提交时间：2025/07/21 nitrogen use efficiency  crop residue substitution  soil nitrogen surplus  subtropical agroecosystems  revised "hole-in-the-pipe" model   PRL-3: unveiling a new horizon in cancer therapy 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 11 作者:  Cao, Zi-tong;  Mao, Jia-luo;  Huang, Chang-ying;  Wang, Han-lin;  Wang, Ming-zhi   |  收藏  |  浏览/下载：13/0  |  提交时间：2025/06/23 Phosphatase of Regenerating Liver-3 (PRL3)  tumor metastasis  targeted therapies  PRL-3-zumab   De Novo Design of Structure-Tunable Multivalent Targeting Chimeras for Tumor-Targeted PD-L1 Degradation and Potentiated Cancer Immunotherapy 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 17 作者:  Zhou, Huiling;  Hou, Bo;  Shan, Yiming;  Huang, Lujia;  Chen, Fangmin   |  收藏  |  浏览/下载：8/0  |  提交时间：2025/06/23 Combinatory therapy, Immune checkpoint blockade, Multivalent targeting chimeras  Tumor microenvironment  Tumor-specific PD-L1 degradation   Cosmological distance forecasts for the CSST Galaxy Survey using BAO peaks 期刊论文  OAI收割 SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2025, 卷号: 68, 期号: 4 作者:  Shi, Feng;  Tian, Jieyi;  Ding, Zhejie;  Yang, Xiaohu;  Gu, Yizhou   |  收藏  |  浏览/下载：79/0  |  提交时间：2025/03/17 large-scale structure  distance scale  cosmology   Synthesis and Evaluation of Optical Properties, SHP2 Inhibitory Activity, and Cellular Imaging for Novel 2-Quinolone Derivatives 期刊论文  OAI收割 ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2025, 页码: 10 作者:  Zhang, Chun;  Yang, Yuting;  Gao, Li-Xin;  Gan, Suya;  Li, Jia   |  收藏  |  浏览/下载：27/0  |  提交时间：2025/05/27 Fluorescent inhibitors  SHP2  2-quinolone derivatives  optical properties  drug tracing  medical diagnosis   Synthesis, fluorescence properties of novel thiazolo[3,2-b][1,2,4]triazol derivatives as potent SHP2 inhibitors and its uses in sensing for Fe3+and cell imaging 期刊论文  OAI收割 JOURNAL OF MOLECULAR STRUCTURE, 2025, 卷号: 1324, 页码: 12 作者:  Yan, Xue;  Zhang, Chun;  Gao, Li-Xin;  Cao, Zi-Tong;  Gan, Su-Ya   |  收藏  |  浏览/下载：35/0  |  提交时间：2025/01/14 Thiazolo[3,2-b][1,2,4]triazole  Salicylic acid  Fe3+ion  Fluorescence property  SHP2