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浏览/检索结果: 共258条，第1-10条 帮助

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Proteasome activation: A novel strategy for targeting undruggable intrinsically disordered proteins 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 145, 页码: 17
作者:  Yu, Qian;  Wang, Zheng;  Tu, Yutong;  Cao, Yu;  Zhu, Huajian
  |  收藏  |  浏览/下载：0/0  |  提交时间：2024/05/07
Discovery of potent PROTAC degraders of Pin1 for the treatment of acute myeloid leukemia 期刊论文  OAI收割
CHEMICAL SCIENCE, 2024, 卷号: 15, 期号: 13, 页码: 5027-5035
作者:  Shi, Yunkai;  Liu, Minmin;  Li, Mengna;  Mao, Yiwen;  Ma, Jingkun
  |  收藏  |  浏览/下载：5/0  |  提交时间：2024/05/07
New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9
作者:  Zheng, Yingying;  Lu, Li;  Li, Mengyue;  Xu, Dehua;  Zhang, Laishun
  |  收藏  |  浏览/下载：8/0  |  提交时间：2024/01/26
Individual Populus euphratica Tree Detection in Sparse Desert Forests Based on Constrained 2-D Bin Packing 期刊论文  OAI收割
IEEE TRANSACTIONS ON GEOSCIENCE AND REMOTE SENSING, 2024, 卷号: 62, 页码: 19
作者:  Wang, Haoyu;  Li, Junli;  Van de Voorde, Tim;  Zhou, Chenghu;  De Maeyer, Philippe
  |  收藏  |  浏览/下载：0/0  |  提交时间：2024/05/27
Structure-based identification of new orally bioavailable BRD9-PROTACs for treating acute myelocytic leukemia 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 18
作者:  Zhang, Jingyu;  Duan, Haiting;  Gui, Renzhao;  Wu, Mingfei;  Shen, Liteng
  |  收藏  |  浏览/下载：12/0  |  提交时间：2023/12/19
Discovery of 5-trifluoromethyl-2-aminopyrimidine derivatives as potent dual inhibitors of FLT3 and CHK1 期刊论文  OAI收割
RSC MEDICINAL CHEMISTRY, 2023, 页码: 14
作者:  Deng, Minjie;  Gao, Yue;  Wang, Peipei;  Du, Wenjing;  Xu, Gaoya
  |  收藏  |  浏览/下载：8/0  |  提交时间：2024/02/19
Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025
作者:  Cheng, Jing;  Yan, Ziqin;  Jiang, Kailong;  Liu, Chen;  Xu, Dehua
  |  收藏  |  浏览/下载：6/0  |  提交时间：2024/02/19
Design, synthesis and biological evaluation of 2-aminopyrimidine derivatives as potent FLT3 inhibitors 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 96, 页码: 5
作者:  Lian, Xuanmin;  Gao, Yue;  Li, Xuemei;  Wang, Peipei;  Tong, Lexian
  |  收藏  |  浏览/下载：7/0  |  提交时间：2023/12/11
Discovery of PVD-06 as a Subtype-Selective and Efficient PTPN2 Degrader 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 22, 页码: 15269-15287
作者:  Hu, Linghao;  Li, Huiyun;  Qin, Junlin;  Yang, Dan;  Liu, Jieming
  |  收藏  |  浏览/下载：27/0  |  提交时间：2024/02/27
Exploration of novel four-membered-heterocycle constructed peptidyl proteasome inhibitors with improved metabolic stability for cancer treatment 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 138, 页码: 22
作者:  Wang, Hanlin;  Wu, Zhaoxiao;  Cao, Yu;  Gao, Lixin;  Shao, Jiaan
  |  收藏  |  浏览/下载：13/0  |  提交时间：2023/10/17