机构

• 上海药物研究所 [46]
• 金属研究所 [15]
• 西北高原生物研究所 [9]
• 计算技术研究所 [3]
• 近代物理研究所 [3]
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采集方式

• OAI收割 [96]
• iSwitch采集 [2]

内容类型

• 期刊论文 [94]
• 会议论文 [3]
• 专利 [1]

发表日期

• 2025 [3]
• 2024 [15]
• 2023 [8]
• 2022 [9]
• 2021 [5]
• 2020 [6]
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学科主题

• 新型燃烧技术 [1]
• 气固两相流与燃烧及其... [1]

筛选

浏览/检索结果: 共98条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Harnessing the Magic Methyl Effect: Discovery of CLPP-2068 as a Novel HsClpP Activator for the Treatment of Diffuse Large B-Cell Lymphoma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 4, 页码: 4287-4307 作者:  Sun, Mingyang;  Chen, Beijing   |  收藏  |  浏览/下载：12/0  |  提交时间：2025/04/01 Design, synthesis, and structure-activity relationship studies of triazolo-pyrimidine derivatives as WRN inhibitors for the treatment of MSI tumors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 282, 页码: 21 作者:  Sui, Qibang;  Zhou, Yuanyang;  Li, Manjia;  Wang, Dan;  Cui, Rongrong   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/12/25 Synthetic lethal  MSI tumors  WRN inhibitors  Triazolo-pyrimidine derivatives   Mutation in CDC42 Gene Set as a Response Biomarker for Immune Checkpoint Inhibitor Therapy 期刊论文  OAI收割 CANCER MEDICINE, 2025, 卷号: 14, 期号: 1, 页码: 13 作者:  Wang, Kun;  Zhang, Yingying;  Su, Zhaoming;  Wang, Bei;  Zhou, Yuanyang   |  收藏  |  浏览/下载：8/0  |  提交时间：2025/04/01 biomarker  CDC42  clinical response  immunotherapy  pan-cancer   SurfDock is a surface-informed diffusion generative model for reliable and accurate protein-ligand complex prediction 期刊论文  OAI收割 NATURE METHODS, 2024, 页码: 24 作者:  Cao, Duanhua;  Chen, Mingan;  Zhang, Runze;  Wang, Zhaokun;  Huang, Manlin   |  收藏  |  浏览/下载：3/0  |  提交时间：2025/01/06 Discovery of CLPP-1071 as an Exceptionally Potent and Orally Efficacious Human ClpP Activator with Strong In Vivo Antitumor Activity 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 21 作者:  Chen, Beijing;  Sun, Mingyang;  Zhang, Chun;  Huang, Qi;  Teng, Dan   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/12/25 Sodium oligomannate disrupts the adherence of Ribhigh bacteria to gut epithelia to block SAA-triggered Th1 inflammation in 5XFAD transgenic mice 期刊论文  OAI收割 CELL DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 19 作者:  Wang, Xinyi;  Xie, Zuoquan;  Yuan, Jie;  Jin, Enjing;  Lian, Wen   |  收藏  |  浏览/下载：11/0  |  提交时间：2024/12/16 Ginkgetin Alleviates Inflammation and Senescence by Targeting STING 期刊论文  OAI收割 ADVANCED SCIENCE, 2024, 页码: 15 作者:  Liu, Yadan;  Ye, Jialin;  Fan, Zisheng;  Wu, Xiaolong;  Zhang, Yinghui   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/12/16 cGAS-STING signaling  Ginkgetin  senescence  STING inhibitor  target identification   Asymmetric macrocyclization enabled by Rh(III)-catalyzed C-H activation: Enantioenriched macrocyclic inhibitor of Zika virus infection 期刊论文  OAI收割 CHINESE CHEMICAL LETTERS, 2024, 卷号: 35, 期号: 11, 页码: 6 作者:  Chen, Chao;  Yu, Wenwen;  Huang, Guangen;  Ren, Xuelian;  Chen, Xiangli   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/09/26 C -H activation  Carboamidation  Enantioselective macrocyclization  Anti-Zika virus activity   An updated patent review of SOS1 inhibitors (2022-present) 期刊论文  OAI收割 EXPERT OPINION ON THERAPEUTIC PATENTS, 2024, 页码: 15 作者:  Zhou, Guizhen;  Zhou, Chuan;  Ma, Xinyi;  Xu, Jiahang;  Zhou, Zehui   |  收藏  |  浏览/下载：3/0  |  提交时间：2024/12/11 SOS1  KRAS  cancer  inhibitor  drug discovery   Addressing fairness issues in deep learning-based medical image analysis: a systematic review 期刊论文  OAI收割 NPJ DIGITAL MEDICINE, 2024, 卷号: 7, 期号: 1, 页码: 16 作者:  Xu, Zikang;  Li, Jun;  Yao, Qingsong;  Li, Han;  Zhao, Mingyue   |  收藏  |  浏览/下载：11/0  |  提交时间：2024/12/06