中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
西北高原生物研究所 [35]
力学研究所 [28]
上海药物研究所 [22]
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期刊论文 [112]
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2024 [11]
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Development of novel epoxyketone macrocyclic peptidyl proteasome inhibitors through OPA-mediated one-step cyclization of unprotected peptides
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 156, 页码: 16
作者:
Zeng, Gongruixue
;
Xu, Gaoya
;
Gao, Lixin
;
Zheng, Xiaoli
;
Chi, Xinglong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/04/01
Proteasome inhibitors
Macrocycle
Stability
Anti-cancer activities
Auto-RapTAC: A Versatile and Sustainable Platform for the Automated Rapid Synthesis and Evaluation of PROTAC
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 15
作者:
Chen, Jiexuan
;
Wu, Mingfei
;
Mo, Jun
;
Hong, Ju
;
Wang, Wei
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/04/01
Discovery of N-Benzylpiperidinol derivatives as USP7 inhibitors against Hematology
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 153, 页码: 13
作者:
Pan, Youlu
;
Chen, Haifeng
;
Fu, Jingfeng
;
Zhang, Jingyu
;
Wang, Peipei
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/10/21
Exploration of novel 20S proteasome activators featuring anthraquinone structures and their application in hypoxic cardiomyocyte protection
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 115, 页码: 10
作者:
Yu, Qian
;
Gao, Lixin
;
Xu, Linhao
;
Han, Yubing
;
Cao, Yu
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/12/11
Enhanced strength-ductility synergy in a gradient hetero-structured CrCoNi medium-entropy alloy
期刊论文
OAI收割
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T, 2024, 卷号: 33, 页码: 7491-7502
作者:
Feng HQ(冯航旗)
;
Zhang HZ(张杭州)
;
He ZH(何政鸿)
;
Zhou LL(周玲玲)
;
Zhang ZH(张子晗)
  |  
收藏
  |  
浏览/下载:76/0
  |  
提交时间:2024/12/19
Gradient nanostructures
Hetero-structures
Strain hardening
Strength-ductility synergy
Medium-entropy alloys
Single-cell sequencing reveals the heterogeneity of pancreatic neuroendocrine tumors under genomic instability and histological grading
期刊论文
OAI收割
ISCIENCE, 2024, 卷号: 27, 期号: 9, 页码: 18
作者:
Ye, Zeng
;
Zhou, Yan
;
Hu, Yuheng
;
Li, Qiang
;
Xu, Zijin
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/11/05
tumor cells
CNV neutral tumor cells
neuroendocrine cells
profile
Stretch-induced hepatic endothelial mechanocrine promotes hepatocyte proliferation
期刊论文
OAI收割
HEPATOLOGY, 2024
作者:
Wu Y(武亿)
;
Li LD(李林达)
;
Li, Wang
;
Li N(李宁)
;
Zhang XY(张晓宇)
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/12/02
HB-EGF
liver regeneration
liver sinusoidal endothelial cell
mechanotransduction
mechanical stretch
Discovery of a Highly Potent and Selective BRD9 PROTAC Degrader Based on E3 Binder Investigation for the Treatment of Hematological Tumors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 28
作者:
Duan, Haiting
;
Zhang, Jingyu
;
Gui, Renzhao
;
Lu, Yang
;
Pang, Ao
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/08/20
Discovery of potent small molecule ubiquitin-specific protease 10 inhibitors with anti-hepatocellular carcinoma activity through regulating YAP expression
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 272, 页码: 21
作者:
Lu, Yang
;
Gao, Jian
;
Wang, Peipei
;
Chen, Haifeng
;
He, Xinjun
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/07/12
Hepatocellular carcinoma
Ubiquitin-specific protease 10
Deubiquitination
Selectivity
Ultrahigh surface hardness and excellent hardness gradient induced by ultrafine dual-carbides in a novel stainless bearing steel
期刊论文
OAI收割
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T, 2024, 卷号: 30, 页码: 7420-7428
作者:
Wang W(王为)
;
Yang MX(杨沐鑫)
;
Wang, Jing
;
Xie JJ(谢季佳)
;
Wang, Jian
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/09/18
Aerospace bearing steel
Ultrahigh surface hardness
Hardness gradient
Dual-carbides
CSS-42L
Case-carburized