机构

• 上海药物研究所 [21]
• 青海盐湖研究所 [11]
• 上海硅酸盐研究所 [6]
• 合肥物质科学研究院 [5]

采集方式

• OAI收割 [43]

内容类型

• 期刊论文 [43]

发表日期

• 2023 [1]
• 2022 [7]
• 2021 [9]
• 2020 [5]
• 2019 [6]
• 2018 [7]
• 更多

学科主题

• Materials ... [1]
• Materials ... [1]
• Metallurgy... [1]

筛选

浏览/检索结果: 共43条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Structure-based identification of new orally bioavailable BRD9-PROTACs for treating acute myelocytic leukemia 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 18 作者:  Zhang, Jingyu;  Duan, Haiting;  Gui, Renzhao;  Wu, Mingfei;  Shen, Liteng   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/19 Acute myeloid leukemia  Bromodomain-containing protein 9  Proteolysis-targeting chimera  Orally bioavailable  Docking   Structure-based rational design enables efficient discovery of a new selective and potent AKT PROTAC degrader 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 238, 页码: 15 作者:  Zhu, Cheng-Liang;  Luo, Xiaomin;  Tian, Tian;  Rao, Zijian;  Wang, Hanlin   |  收藏  |  浏览/下载：28/0  |  提交时间：2022/08/16 AKT  Protein kinase B  PROTAC  Chemical degrader  Rational design   Structural Feature Analyzation Strategies toward Discovery of Orally Bioavailable PROTACs of Bruton's Tyrosine Kinase for the Treatment of Lymphoma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 13, 页码: 9096–9125 作者:  Zhang, Jingyu;  Che, Jinxin;  Luo, Xiaomin;  Wu, Mingfei;  Kan, Weijuan   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/03/21 Design, synthesis and biological evaluation of sulfonamides inhibitors of XPO1 displaying activity against multiple myeloma cells 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 235 作者:  Qu, Bingxue;  Xu, Yongjin;  Lu, Yang;  Zhuang, Weihao;  Jin, Xinxin   |  收藏  |  浏览/下载：24/0  |  提交时间：2022/12/23 XPO1  Multiple myeloma  MM.1S  N-phenylsulfonamide  Oral administration   Microstructural and mechanical evolution of SiCf/SiC composites in wet oxygen atmosphere above 1000 degrees C 期刊论文  OAI收割 CERAMICS INTERNATIONAL, 2022, 卷号: 48, 期号: 6, 页码: 8473-8480 作者:  Guo, Feiyu;  Chen, Xiaowu;  Cheng, Guofeng;  Wu, Huiyang;  Zhou, Haijun   |  收藏  |  浏览/下载：32/0  |  提交时间：2022/06/15 Wet-oxygen  SiCf/SiC  Residual stress  Bending strength  Raman spectra   Identification of 2-Aminopyrimidine Derivatives as FLT3 Kinase Inhibitors with High Selectivity over c-KIT 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 4, 页码: 3229-3248 作者:  Tong, Lexian;  Wang, Peipei;  Li, Xuemei;  Dong, Xiaowu;  Hu, Xiaobei   |  收藏  |  浏览/下载：18/0  |  提交时间：2022/08/16 Discovery of seneciobipyrrolidine derivatives for the amelioration of glucose homeostasis disorders through 4E-BP1/Akt/AMPK signaling activation 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 228, 页码: 25 作者:  Che, Jinxin;  Ma, Canliang;  Lu, Jialiang;  Chen, Binhui;  Shi, Qiuqiu   |  收藏  |  浏览/下载：30/0  |  提交时间：2022/06/15 Seneciobipyrrolidine  Phenotypic screening  Glucose homeostasis  Proteomic analysis  L6 myotubes  4E-BP1   High efficacy of PD-1 inhibitor after initial failure of PD-L1 inhibitor in Relapsed/Refractory classical Hodgkin Lymphoma 期刊论文  OAI收割 BMC CANCER, 2022, 卷号: 22 作者:  Chen, Xi;  Kong, Haiying;  Luo, Linxiang;  Han, Shuiyun;  Lei, Tao   |  收藏  |  浏览/下载：55/0  |  提交时间：2022/02/14 Hodgkin lymphoma  PD-1 inhibitor  PD-L1 inhibitor  PD-L2  Molecular phenotype  Tumor microenvironment   Discover Novel Covalent Inhibitors Targeting FLT3 through Hybrid Virtual Screening Strategy 期刊论文  OAI收割 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2021, 卷号: 44, 期号: 12, 页码: 1872-1877 作者:  Hu, Shengquan;  Liu, Jing;  Chen, Sikang;  Gao, Jian;  Zhou, Yubo   |  收藏  |  浏览/下载：21/0  |  提交时间：2022/06/15 acute myeloid leukemia  FMS-like tyrosine kinase 3  CovDock  hybrid virtual screening  autodock   Effects of interfacial residual stress on mechanical behavior of SiCf/SiC composites 期刊论文  OAI收割 JOURNAL OF ADVANCED CERAMICS, 2021, 页码: 11 作者:  Chen, Xiaowu;  Cheng, Guofeng;  Yang, Jinshan;  Hu, Jianbao;  Liao, Chunjin   |  收藏  |  浏览/下载：69/0  |  提交时间：2021/12/01 ceramic matrix composites  Raman spectroscopy  mechanical properties  residual stress