机构

• 上海药物研究所 [14]
• 水土保持研究所 [4]

采集方式

• OAI收割 [18]

内容类型

• 期刊论文 [17]
• 会议论文 [1]

发表日期

• 2023 [1]
• 2021 [1]
• 2018 [2]
• 2017 [2]
• 2016 [1]
• 2015 [3]
• 更多

学科主题

筛选

浏览/检索结果: 共18条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance 期刊论文  OAI收割 EMBO MOLECULAR MEDICINE, 2023, 页码: 24 作者:  Wang, Li-Min;  Wang, Pingyuan   |  收藏  |  浏览/下载：51/0  |  提交时间：2023/04/10 homologous recombination repair  olaparib-resistant  PARP inhibitor  PARP7  type I interferons   Design, Synthesis, and Pharmacological Evaluation of Biaryl-Containing PD-1/PD-L1 Interaction Inhibitors Bearing a Unique Difluoromethyleneoxy Linkage 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 22, 页码: 16687-16702 作者:  Song, Zilan;  Liu, Bo;  Peng, Xia;  Gu, Wangting;  Sun, Yiming   |  收藏  |  浏览/下载：32/0  |  提交时间：2022/06/15 Design, synthesis and biological evaluation of a series of novel 2-benzamide-4-(6-oxy-N-methyl-l-naphthamide)-pyridine derivatives as potent fibroblast growth factor receptor (FGFR) inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 154, 页码: 9-28 作者:  Wei, Manman;  Peng, Xia;  Xing, Li;  Dai, Yang;  Huang, Ruimin   |  收藏  |  浏览/下载：66/0  |  提交时间：2019/01/08 FGFR  VEGFR  Synergistic effect  Tumor growth inhibition  Lucitanib   Discovery of 2,4-diarylaminopyrimidines bearing a resorcinol motif as novel ALK inhibitors to overcome the G1202R resistant mutation 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 144, 页码: 386-397 作者:  Geng, Kaijun;  Xia, Zongjun;  Ji, Yinchun;  Zhang, Ruisi (Ruthy);  Sun, Deqiao   |  收藏  |  浏览/下载：168/0  |  提交时间：2019/01/08 ALK  G1202R mutant  Drug resistance  2,4-Diarylaminopyrimidine  Resorcinol   Synthesis and structure-activity relationship study of pyrazolo[3,4-d]pyrimidines as tyrosine kinase RET inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 11, 页码: 2544-2548 作者:  Wang, Chengyan;  Liu, Hongchun;  Song, Zilan;  Ji, Yinchun;  Xing, Li   |  收藏  |  浏览/下载：42/0  |  提交时间：2019/01/08 Tyrosine kinase RET  Pyrazolo[3,4-d]pyrimidine  Anticancer  Cell proliferation  Structure-activity relationship   Poly(ADP-ribose)polymerase (PARP) inhibition and anticancer activity of simmiparib, a new inhibitor undergoing clinical trials 期刊论文  OAI收割 CANCER LETTERS, 2017, 卷号: 386, 页码: 47-56 作者:  Yuan, Bo;  Ye, Na;  Song, Shan-Shan;  Wang, Yu-Ting;  Song, Zilan   |  收藏  |  浏览/下载：59/0  |  提交时间：2019/01/08 Homologous recombination repair defects  Olaparib  Growth inhibition  Patient-derived xenografts  Pharmacokinetics   An orally available tyrosine kinase ALK and RET dual inhibitor bearing the tetracyclic benzo[b]carbazolone core 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 118, 页码: 244-249 作者:  Song, Zilan;  Xia, Zongjun;  Ji, Yinchun;  Xing, Li;  Gao, Yinglei   |  收藏  |  浏览/下载：78/0  |  提交时间：2019/01/08 Benzo[b]carbazolones  ALK inhibitors  RET kinase  Antiresistance  Non-small-cell lung cancer  Preclinical study   Novel tetracyclic benzo[b]carbazolones as highly potent and orally bioavailable ALK inhibitors: Design, synthesis, and structure-activity relationship study 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 105, 页码: 39-56 作者:  Jiang, Xiaolong;  Zhou, Ji;  Ai, Jing;  Song, Zilan;  Peng, Xia   |  收藏  |  浏览/下载：62/0  |  提交时间：2019/01/08 Benzo[b]carbazolones  ALK inhibitors  Anti-cancer  Anti-resistance  Non-small-cell lung cancer   Discovery and SAR study of c-Met kinase inhibitors bearing an 3-amino-benzo[d] isoxazole or 3-aminoindazole scaffold 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2015, 卷号: 23, 期号: 3, 页码: 564-578 作者:  Jiang, Xiaolong;  Liu, Hongyan;  Song, Zilan;  Peng, Xia;  Ji, Yinchun   |  收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 c-Met kinase  Inhibitor  3-Amino-benzo[d]isoxazole  3-Aminoindazole  Non-small cell lung cancer   Discovery of Novel 2,4-Diarylaminopyrimidine Analogues (DAAPalogues) Showing Potent Inhibitory Activities against Both Wild-type and Mutant ALK Kinases 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 58, 期号: 1, 页码: 197-211 作者:  Song, Zilan;  Yang, Yanhong;  Liu, Zhiqing;  Peng, Xia;  Guo, Junfeng   |  收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08