机构

• 水生生物研究所 [19]
• 上海药物研究所 [6]

采集方式

• OAI收割 [25]

内容类型

• 期刊论文 [24]
• 学位论文 [1]

发表日期

• 2024 [1]
• 2023 [1]
• 2022 [1]
• 2021 [2]
• 2019 [1]
• 2012 [4]
• 更多

学科主题

• Ecology; L... [2]
• Environmen... [2]
• Physical G... [2]
• Environmen... [1]

筛选

浏览/检索结果: 共25条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of an Ortho-Substituted N-Cyclopropylmethyl-7α-phenyl-6,14-endoethano-tetrahydronorthebaine Derivative as a Selective and Potent Kappa Opioid Receptor Agonist with Subsided Sedative Effect 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 9, 页码: 7112-7129 作者:  Li, Zixiang;  Ye, Rufeng;  He, Qian;  Lu, Jiashuo;  Sun, Yanting   |  收藏  |  浏览/下载：25/0  |  提交时间：2024/06/27 Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 15 作者:  Kong, Linghui;  Ning, Kuan;  Liu, Xiao;  Lu, Jiashuo;  Chen, Baiyu   |  收藏  |  浏览/下载：38/0  |  提交时间：2023/10/17 N-cyclopropylmethyl nornepenthone derivatives  derivatives  Structure-activity relationship  MOR antagonist  Functional reversal  Reversal of subtype-selectivity  Opioid use disorder   SLL-627 Is a Highly Selective and Potent ? Opioid Receptor (KOR) Agonist with an Unexpected Nonreduction in Locomotor Activity 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 16 作者:  Kong, Linghui;  Shu, Xuelian;  Tang, Siyuan;  Ye, Rongrong;  Sun, Huijiao   |  收藏  |  浏览/下载：60/0  |  提交时间：2022/08/30 Discovery of an M-Substituted N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaine as a Selective, Potent, and Orally Active kappa-Opioid Receptor Agonist with an Improved Central Nervous System Safety Profile 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12414-12433 作者:  He, Qian;  Wei, Yuanyuan;  Liu, Xiao;  Ye, Rongrong;  Kong, Linghui   |  收藏  |  浏览/下载：91/0  |  提交时间：2021/11/04 Exploration of the SAR Connection between Morphinan- and Arylacetamide-Based kappa Opioid Receptor (kappa OR) Agonists Using the Strategy of Bridging 期刊论文  OAI收割 ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 6, 页码: 1018-1030 作者:  Liu, Xiao;  Jiang, Shuang;  Kong, Linghui;  Ye, Rongrong;  Xiao, Li   |  收藏  |  浏览/下载：99/0  |  提交时间：2021/05/24 Morphinans  arylacetamidyl substituent  kappa opioid receptor modulators  structure-activity relationships   Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070 作者:  Xiao, Li;  Wang, Yujun;  Zhang, Mumei;  Wu, Weiwei;  Kong, Linghui   |  收藏  |  浏览/下载：90/0  |  提交时间：2020/07/01 Spatial Distribution of Macroinvertebrate Community along a Longitudinal Gradient in a Eutrophic Reservoir-Bay during Different Impoundment Stages, China 期刊论文  OAI收割 INTERNATIONAL REVIEW OF HYDROBIOLOGY, 2012, 卷号: 97, 期号: 3, 页码: 169-183 作者:  Zhang, Min;  Cai, Qinghua;  Xu, Yaoyang;  Kong, Linghui;  Tan, Lu   |  收藏  |  浏览/下载：30/0  |  提交时间：2012/09/25 Longitudinal Distribution  Zonation  Impoundment  Xiangxi Bay  Three Gorges Reservoir   ZONATION AND ITS INFLUENCING FACTORS OF A LARGE SUBTROPICAL RESERVOIR (DANJIANGKOU RESERVOIR IN CENTRAL CHINA), BASED ON MACROINVERTEBRATES 期刊论文  OAI收割 FRESENIUS ENVIRONMENTAL BULLETIN, 2012, 卷号: 21, 期号: 8, 页码: 2095-2104 作者:  Zhang, Min;  Cai, Qinghua;  Xu, Yaoyang;  Wang, Lan;  Kong, Linghui 收藏  |  浏览/下载：30/0  |  提交时间：2013/01/09 Reservoir zonation  macroinvertebrates  RWCS  organic matter  seasonal change   丹江口水库生态系统健康综合评价 期刊论文  OAI收割 应用与环境生物学报, 2012, 期号: 1 张红叶; 蔡庆华; 孔令惠; 徐耀阳; 张敏; 王岚 收藏  |  浏览/下载：16/0  |  提交时间：2013/01/21 丹江口水库  水域生态系统  健康状态评价  营养状态评价  时空差异   洱海流域湖泊生态系统健康综合评价与比较 期刊论文  OAI收割 中国环境科学, 2012, 期号: 4 张红叶; 蔡庆华; 唐涛; 汪兴中; 杨顺益; 孔令惠 收藏  |  浏览/下载：47/0  |  提交时间：2013/01/21 洱海流域  高原湖泊  生态系统健康  营养状态评价  空间差异