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Design, synthesis and structure-activity relationship studies of novel macrocyclic 2,4-diaminopyrimidines as HPK1 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 12
作者:
Wu, Feifei
;
Sun, Jiaqi
;
Xu, Mingyang
;
Li, Huiyu
;
Wei, Jiarui
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Macrocycle
Kinase
Inhibitors
HPK1
Cancer immunotherapy
Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CL
pro
inhibitors against SARS-CoV-2
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 11
作者:
Guma, Samuel Desta
;
Song, Kang
;
Sun, Haiguo
;
Yang, Lei
;
Zhou, Zhaoyin
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
SARS-CoV-2
3CL(pro) inhibitors
Thioamide derivatives
Spiropyrrolidine derivatives
Nirmatrelvir
HCoV-OC43
Antiviral
Metabolic stability
Evolution behavior of competing fatigue failure and life prediction related to defect, stress and temperature for laser powder bed fused superalloy with solution aging treatment
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF FATIGUE, 2025, 卷号: 198, 页码: 17
作者:
Sun, Chuanwen
;
Li, Wei
;
Liu, Gang
;
Sun, Rui
;
Wang, Chuanpeng
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/07/22
Laser powder bed fusion
Nickel-based superalloy
Elevated temperature fatigue
Internal failure evolution
Life prediction
Inhibition of α-synuclein aggregation by MCC950 attenuates dopaminergic neuronal damage in MN9D cells
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACOLOGY, 2025, 卷号: 1001, 页码: 10
作者:
Gao, Huiwen
;
Liang, Yingneng
;
Wang, Mengfei
;
Li, Wen
;
Zheng, Wei
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/08/20
alpha-synuclein
MCC950
Parkinson's disease
Neuroprotection
Cryogenic 3D printing of damage tolerant hierarchical porous ceramics
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF EXTREME MANUFACTURING, 2025, 卷号: 7, 期号: 4, 页码: 11
作者:
Zhu, Zheng
;
Gao, Dandan
;
Huang, Zhuo
;
Chang, Wei
;
Wu, Bin
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2025/04/27
hierarchical structure
bioinspired designs
energy absorption
damage tolerance
3D printing
High-resolution Solar Image Registration Using Unsupervised Deep Learning
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL, 2025, 卷号: 988, 期号: 2
作者:
Zhang, Hao
;
Liang, Bo
;
Yan XL(闫晓理)
;
Feng, Song
;
Yuan, Ding
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2025/08/11
EP240801a/XRF 240801B: An X-Ray Flash Detected by the Einstein Probe and the Implications of Its Multiband Afterglow
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2025, 卷号: 988, 期号: 1
作者:
Jiang, Shuai-Qing
;
Xu, Dong
;
Hoof, Agnes P. C. van
;
Lei, Wei-Hua
;
Liu, Yuan
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/07/28
First polarization study of the M87 jet and active galactic nuclei at submillimeter wavelengths with ALMA
期刊论文
OAI收割
ASTRONOMY & ASTROPHYSICS, 2025, 卷号: 699
作者:
Goddi, Ciriaco
;
Carlos, Douglas F.
;
Crew, Geoffrey B.
;
Matthews, Lynn D.
;
Messias, Hugo
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/08/25
black hole physics
magnetic fields
polarization
radiation mechanisms: non-thermal
instrumentation: interferometers
instrumentation: polarimeters
Identification of candidate genes and SNPs associated with growth traits by genome-wide association study (GWAS) in sea cucumber
(Apostichopus
japonicus)
期刊论文
OAI收割
AQUACULTURE, 2025, 卷号: 605, 页码: 10
作者:
Cui, Wei
;
Su, Fang
;
Liu, Shilin
;
Zhang, Libin
;
Yang, Hongsheng
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/07/11
Sea cucumber ( Apostichopus japonicus )
Growth traits
GWAS
Genomic selection
Linaggrenoids A-I, structurally diverse lindenane sesquiterpenoids with anti-hepatic fibrosis effects from
Lindera aggregata
期刊论文
OAI收割
PHYTOCHEMISTRY, 2025, 卷号: 235, 页码: 10
作者:
Li, Wen-Xian
;
Gan, Lu
;
Liao, Yi-Ling
;
Wu, Yu-Wei
;
Zhang, Bai-Hui
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/05/27
Lindera aggregata
Lauraceae
Lindenane sesquiterpenoid
Anti-hepatic fibrosis activity