中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [28]
合肥物质科学研究院 [27]
上海应用物理研究所 [13]
国家授时中心 [6]
高能物理研究所 [5]
青岛生物能源与过程研... [3]
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期刊论文 [78]
专利 [14]
会议论文 [6]
成果 [1]
研究报告 [1]
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2025 [2]
2023 [4]
2022 [11]
2021 [3]
2020 [19]
2019 [12]
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应用光学技术::光学... [6]
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A nanobody-enzyme fusion protein targeting PD-L1 and sialic acid exerts anti-tumor effects by C-type lectin pathway-mediated tumor associated macrophages repolarizing
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 卷号: 298, 页码: 13
作者:
Tong, Yongliang
;
Chen, Runqiu
;
Lu, Xinrong
;
Chen, Cuiying
;
Sun, Guiqin
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/04/01
Glycol-immunology
Nanobody-enzyme fusion protein
Sialic acid
Design, Synthesis, and Pharmacological Evaluation of Quinazoline and Quinoline Derivatives as Potent ENPP1 Inhibitors for Cancer Immunotherapy
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 18
作者:
He, Jie
;
Ma, Xiaoyu
;
Sun, Jia
;
Chen, Manman
;
Xu, Lan
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/04/01
Discovery of Urea Derivatives of Celastrol as Selective Peroxiredoxin 1 Inhibitors against Colorectal Cancer Cells
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 9, 页码: 7176-7196
作者:
Li, Yang
;
Zhu, Yuyuan
;
Shang, Fan-Fan
;
Xu, Lin
;
Jiang, Defang
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2024/06/27
Effect of an Herbal-Based Injection on 28-Day Mortality in Patients With Sepsis The EXIT-SEP Randomized Clinical Trial
期刊论文
OAI收割
JAMA INTERNAL MEDICINE, 2023, 卷号: 183, 期号: 7, 页码: 647-655
作者:
Liu, Songqiao
;
Yao, Chen
;
Xie, Jianfeng
;
Liu, Hong
;
Wang, Hongliang
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2024/03/27
Recent advances of activation techniques-based discovery of new compounds from marine fungi
期刊论文
OAI收割
FITOTERAPIA, 2023, 卷号: 167, 页码: 14
作者:
Zou, Ran
;
Chen, Bao
;
Sun, Jie
;
Guo, Yue-Wei
;
Xu, Baofu
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
Marine fungi
Silent
Biosynthetic gene clusters
Activation techniques
Scalarane sesterterpenes from the South China Sea sponge Hyrtios erecta and their PTP1B inhibitory activity
期刊论文
OAI收割
TETRAHEDRON, 2023, 卷号: 137, 页码: 5
作者:
Sun, Li-Li
;
Shen, Yi-Ran
;
Li, Jia
;
Wang, Jian-Rong
;
Li, Xu-Wen
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2023/10/17
Sponge
Hyrtios erecta
Scalarane-type sesterterpene
Configuration
PTP1B
Optimization of carbazole carboxamide RORγt agonists: Challenges in improving the metabolic stability and maintaining the agonistic activity
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 251, 页码: 115213
作者:
Sun, Nannan
;
Yu, Mingcheng
;
Jiang, Zhengyuan
;
Yang, Feng
;
Lu, Lixue
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/03/27
ROR?t agonists
Carbazole carboxamide
Agonistic activity
Metabolic stability
Co-crystallization
Molecular docking
Investigation of atropisomeric transformation of a novel PDE4 inhibitor with tetrahydroisoquinoline-based amide group and its primary study of binding to HSA
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2022, 卷号: 221, 页码: 5
作者:
Chen, Huanhuan
;
Zhu, Tingfei
;
Sun, Ling
;
Xiang, Lili
;
Han, Haiyun
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2023/04/10
Atropisomer
Restricted rotation
Kinetic
Energy barrier
Dynamic HPLC
HSA binding
Morphological Modulation of Co2C by Surface-Adsorbed Species for Highly Effective Low-Temperature CO2Reduction
期刊论文
OAI收割
ACS Catalysis, 2022, 卷号: 12, 期号: 14, 页码: 8544-8557
作者:
Zhang, Shunan
;
Liu, Xiaofang
;
Luo, Hu
;
Wu, Zhaoxuan
;
Wei, Baiyin
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2023/06/26
Carbides - Carbon - Chemical shift - Cobalt compounds - Fischer-Tropsch synthesis - Manganese compounds - Reaction kinetics - Temperature - Transition metals - Water gas shift
Enhanced mangrove vegetation index based on hyperspectral images for mapping mangrove
期刊论文
OAI收割
ISPRS JOURNAL OF PHOTOGRAMMETRY AND REMOTE SENSING, 2022, 卷号: 189, 页码: 236-254
作者:
Yang, Gang
;
Huang, Ke
;
Sun, Weiwei
;
Meng, Xiangchao
;
Mao, Dehua
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2022/09/21
Mangrove
Vegetation index
Mangrove Vegetation Index (MVI)
Hyperspectral imagery
ZY1-02D