中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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海洋研究所 [40]
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期刊论文 [148]
CNKI期刊论文 [2]
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2025 [5]
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Design, synthesis and structure-activity relationship studies of novel macrocyclic 2,4-diaminopyrimidines as HPK1 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 12
作者:
Wu, Feifei
;
Sun, Jiaqi
;
Xu, Mingyang
;
Li, Huiyu
;
Wei, Jiarui
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Macrocycle
Kinase
Inhibitors
HPK1
Cancer immunotherapy
Solid-state screening and dry powder inhaler development of ziyuglycoside II sodium salt for enhanced bioavailability
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2025, 卷号: 681, 页码: 11
作者:
Zhang, Hanwen
;
Wang, Siwen
;
Slimani, Sara
;
Lv, Yuting
;
Nie, Qin
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/08/20
Bioavailability
Dry powder inhaler
Saponin
Solid-state screening
Ziyuglycoside II sodium salt
Tracheal Targeted Nanogrid Delivery Systems of Dexamethasone Visualized by Single-Particle Tracing and Multiscale Pathological Mapping
期刊论文
OAI收割
ACS NANO, 2025, 卷号: 19, 期号: 25, 页码: 23414-23430
作者:
Cao, Zeying
;
Zhou, Shilin
;
Zhao, Yanli
;
Wu, Qian
;
Huang, Chenxi
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
three-dimensional pathology
nanogrid
ROS-scavenging
tracheal targeted
bronchitis
nano-bio-interactions
Design, Synthesis, and biological evaluation of 7H-Pyrrolo[2,3-d] pyrimidines as potent HPK1 kinase inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 119, 页码: 13
作者:
Wu, Feifei
;
Li, Huiyu
;
Li, Weiqiang
;
Zhang, Laishun
;
An, Qi
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/04/01
Optimization
Hematopoietic progenitor kinase 1
Inhibitor
Cancer immunotherapy
Targeting QPCTL: An Emerging Therapeutic Opportunity
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 2, 页码: 929-943
作者:
Yu, Lei
;
Sun, Yaoliang
;
Xie, Longyan
;
Tan, Xiao
;
Wang, Ping
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2025/04/01
Discovery of an Efficacious RET PROTAC Degrader with Enhanced Antiproliferative Activity against Resistant Cancer Cells Harboring RET Solvent-Front Mutations
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 68, 期号: 1, 页码: 753-775
作者:
Zhang, Qian
;
He, Yingqi
;
Rao, Danni
;
He, Rui
;
Yu, Lei
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2025/02/28
Discovery of Pyrido[2,3-
d
]pyrimidin-7-one Derivatives as Highly Potent and Efficacious Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1) Inhibitors for Cancer Treatment
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 5, 页码: 3986-4006
作者:
Sun, Yaoliang
;
Chen, Manman
;
Han, Yuyan
;
Li, Weiqiang
;
Ma, Xiaoyu
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2024/05/07
Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 16
作者:
Sun, Yaoliang
;
Chen, Zhiwen
;
Liu, Guobin
;
Chen, Xiaoai
;
Shi, Zihan
  |  
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2024/03/25
Inhibitor
Cancer
Threonine tyrosine kinase (TTK)
Covalent
Discovery and Structural Optimization of Covalent ZAP-70 Kinase Inhibitors against Psoriasis
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 15
作者:
Rao, Danni
;
Yang, Tao
;
Feng, Huixu
;
An, Qi
;
Zhang, Shaofeng
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2023/10/17
Microplastics in canned, salt-dried, and instant sea cucumbers sold for human consumption
期刊论文
OAI收割
MARINE POLLUTION BULLETIN, 2023, 卷号: 192, 页码: 8
作者:
Mohsen, Mohamed
;
Lin, Chenggang
;
Abdalla, Mohnad
;
Liu, Shilin
;
Yang, Hongsheng
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2023/12/07
Seafood
Microplastics
Human consumption
Sea cucumbers
Microfibers
Molecular docking