中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [20]
云南天文台 [19]
近代物理研究所 [9]
地理科学与资源研究所 [8]
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期刊论文 [100]
专利 [4]
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会议论文 [2]
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2024 [3]
2020 [4]
2019 [3]
2018 [9]
2017 [18]
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Astronomy... [12]
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光电子学与激光技术 [1]
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物理化学与绿色催化 [1]
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Discovery of 2,4-quinazolinedione derivatives as LC3B recruiters in the facilitation of protein complex degradations
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 287, 页码: 10
作者:
Zeng, Yanping
;
Xiao, Jian
;
Shi, Li
;
Li, Yangsha
;
Xu, Yuanxin
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2025/04/01
LC3B
CDK9
Degradation
Protein complex
Single Amine or Guanidine Modification on Norvancomycin and Vancomycin to Overcome Multidrug-Resistance through Augmented Lipid II Binding and Increased Membrane Activity
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 22, 页码: 20639-20663
作者:
Bian, Xiaolei
;
Chen, Zhifu
;
Li, Fang
;
Xie, Yuanyuan
;
Li, Yi
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/12/11
Structural Optimization of Isoquinoline Derivatives from Lycobetaine and Their Inhibitory Activity against Neuroendocrine Prostate Cancer Cells
期刊论文
OAI收割
MOLECULES, 2024, 卷号: 29, 期号: 18, 页码: 28
作者:
Zhang, Zhuo
;
Shen, Qianqian
;
Ji, Yiyi
;
Ma, Yanjie
;
Hou, Haiyang
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/11/05
NEPC
natural product
natural product derivatives
lycobetaine
A novel BODIPY-based theranostic agent for
in vivo
fluorescence imaging of cerebral Aβ and ameliorating Aβ-associated disorders in Alzheimer's disease transgenic mice
期刊论文
OAI收割
RSC MEDICINAL CHEMISTRY, 2024, 页码: 9
作者:
Zhang, Jingjing
;
Ren, Wenming
;
Liu, Xiaohui
;
Chen, Jingjing
;
Zeng, Yuteng
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/05/07
Crop/Plant Modeling Supports Plant Breeding II. Guidance of Functional Plant Phenotyping for Trait Discovery
期刊论文
OAI收割
PLANT PHENOMICS, 2023, 卷号: 5, 页码: 19
作者:
Zhang, Pengpeng
;
Huang, Jingyao
;
Ma, Yuntao
;
Wang, Xiujuan
;
Kang, Mengzhen
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/02/22
Discovery of (S)-N-(2-Amino-4-fluorophenyl)-4-(1-(3-(4-((dimethylamino)methyl)phenyl)-6-oxopyridazin-1(6H)-yl)ethyl)benzamide as Potent Class I Selective HDAC Inhibitor for Oral Anticancer Drug Candidate
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 10, 页码: 7016-7037
作者:
Li, Daqiang
;
Zhang, Zhuo
;
Li, Yalei
;
Wang, Xinyi
;
Zhong, Hanyue
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/10/17
Preparation, characterization and in vivo efficacy evaluation of ropivacaine O/W emulsion by premix membrane emulsification
期刊论文
OAI收割
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2022, 卷号: 640, 页码: 9
作者:
Yuan, Miaomiao
;
Na, Xiangming
;
Liu, Jingxuan
;
Zhang, Youhong
;
Wei, Yi
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/06/15
Ropivacaine emulsion
Premix membrane emulsion
Sciatic nerve blockade model
Cutaneous trunci pinprick model
Safety evaluation
Interactions between typical functional groups of soil organic matter and mica (001) surface: A DFT study
期刊论文
OAI收割
APPLIED CLAY SCIENCE, 2022, 卷号: 216, 页码: 106374
作者:
Zhang, Hongping
;
Chen, Meng
;
Sun, Chenghua
;
Tang, Youhong
;
Ni, Yuxiang
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/09/18
GPR52 Antagonist Reduces Huntingtin Levels and Ameliorates Huntington's Disease-Related Phenotypes
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 2, 页码: 941-957
作者:
Wang, Congcong
;
Zhang, Yu-Fang
;
Guo, Shimeng
;
Zhao, Quan
;
Zeng, Yanping
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/05/24
Discovery of selective HDAC/BRD4 dual inhibitors as epigenetic probes
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 20
作者:
Chen, Jingjing
;
Li, Yalei
;
Zhang, Jie
;
Zhang, Minmin
;
Wei, Aihuan
  |  
收藏
  |  
浏览/下载:76/0
  |  
提交时间:2021/05/24
HDAC
BRD4
Selective dual inhibitors
Anticancer