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浏览/检索结果: 共114条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择发表日期升序发表日期降序题名升序题名降序提交时间升序提交时间降序作者升序作者降序 Multiplexed Isotope-Coded Mass Spectrometry Footprinting Enables Broad Heteroatom-Residue Mapping and Uncovers Noncanonical Ligand-Binding Sites in Amyloidosis Proteins 期刊论文  OAI收割 ANALYTICAL CHEMISTRY, 2026, 页码: 13 作者:  Yang, Kuoqi   |  收藏  |  浏览/下载：4/0  |  提交时间：2026/04/01 Design, synthesis, and biological evaluation of KDM5B degraders against hematologic malignancy cells 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17 作者:  Liu, Xiaowen;  Li, Jiarong;  Guo, Yihao   |  收藏  |  浏览/下载：9/0  |  提交时间：2025/12/04 KDM5B  PROTAC  TPD  Hematological malignancy   Fine structural design of 3βHSD1 inhibitors for prostate cancer 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2025, 卷号: 122, 期号: 26, 页码: 12 作者:  He, Dongyin;  Zhang, Luyao;  Yu, Leiye;  Zhang, Yuhang   |  收藏  |  浏览/下载：3/0  |  提交时间：2025/09/09 prostate cancer  drug development  AlphaFold  molecular simulations  3 beta 3HSD1   Novel Aryl Sulfonium Modification on Vancomycin to Tackle MRSA and VRE In Vitro and In Vivo through Dual Enhanced Cell-Wall and Membrane Inhibition 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 8, 页码: 8310-8329 作者:  Xie, Yuanyuan;  Wang, Xiaowen;  Chang, Taopeng;  Chen, Zhifu;  Luo, Youhong   |  收藏  |  浏览/下载：40/0  |  提交时间：2025/06/23 Discovery of 2,4-quinazolinedione derivatives as LC3B recruiters in the facilitation of protein complex degradations 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 287, 页码: 10 作者:  Zeng, Yanping;  Xiao, Jian;  Shi, Li;  Li, Yangsha;  Xu, Yuanxin   |  收藏  |  浏览/下载：121/0  |  提交时间：2025/04/01 LC3B  CDK9  Degradation  Protein complex   Single Amine or Guanidine Modification on Norvancomycin and Vancomycin to Overcome Multidrug-Resistance through Augmented Lipid II Binding and Increased Membrane Activity 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 22, 页码: 20639-20663 作者:  Bian, Xiaolei;  Chen, Zhifu;  Li, Fang;  Xie, Yuanyuan;  Li, Yi   |  收藏  |  浏览/下载：61/0  |  提交时间：2024/12/11 Structural Optimization of Isoquinoline Derivatives from Lycobetaine and Their Inhibitory Activity against Neuroendocrine Prostate Cancer Cells 期刊论文  OAI收割 MOLECULES, 2024, 卷号: 29, 期号: 18, 页码: 28 作者:  Zhang, Zhuo;  Shen, Qianqian;  Ji, Yiyi;  Ma, Yanjie;  Hou, Haiyang   |  收藏  |  浏览/下载：63/0  |  提交时间：2024/11/05 NEPC  natural product  natural product derivatives  lycobetaine   A novel BODIPY-based theranostic agent for in vivo fluorescence imaging of cerebral Aβ and ameliorating Aβ-associated disorders in Alzheimer's disease transgenic mice 期刊论文  OAI收割 RSC MEDICINAL CHEMISTRY, 2024, 页码: 9 作者:  Zhang, Jingjing;  Ren, Wenming;  Liu, Xiaohui;  Chen, Jingjing;  Zeng, Yuteng   |  收藏  |  浏览/下载：55/0  |  提交时间：2024/05/07 Crop/Plant Modeling Supports Plant Breeding II. Guidance of Functional Plant Phenotyping for Trait Discovery 期刊论文  OAI收割 PLANT PHENOMICS, 2023, 卷号: 5, 页码: 19 作者:  Zhang, Pengpeng;  Huang, Jingyao;  Ma, Yuntao;  Wang, Xiujuan;  Kang, Mengzhen   |  收藏  |  浏览/下载：56/0  |  提交时间：2024/02/22 Discovery of (S)-N-(2-Amino-4-fluorophenyl)-4-(1-(3-(4-((dimethylamino)methyl)phenyl)-6-oxopyridazin-1(6H)-yl)ethyl)benzamide as Potent Class I Selective HDAC Inhibitor for Oral Anticancer Drug Candidate 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 10, 页码: 7016-7037 作者:  Li, Daqiang;  Zhang, Zhuo;  Li, Yalei;  Wang, Xinyi;  Zhong, Hanyue   |  收藏  |  浏览/下载：52/0  |  提交时间：2023/10/17