机构

• 上海药物研究所 [88]
• 上海光学精密机械研... [35]
• 自动化研究所 [2]
• 地理科学与资源研究所 [1]
• 广州地球化学研究所 [1]
• 中国科学院大学 [1]
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采集方式

• OAI收割 [128]
• iSwitch采集 [1]

内容类型

• 期刊论文 [128]
• 学位论文 [1]

发表日期

• 2024 [12]
• 2023 [51]
• 2022 [28]
• 2020 [1]
• 2018 [1]
• 2016 [10]
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学科主题

• 等离子体物理 [1]

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浏览/检索结果: 共129条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序题名升序题名降序作者升序作者降序发表日期升序发表日期降序 Integrated multi-omics analysis reveals gut microbiota dysbiosis and systemic disturbance in major depressive disorder 期刊论文  OAI收割 PSYCHIATRY RESEARCH, 2024, 卷号: 334, 页码: 12 作者:  Xie, Zuoquan;  Huang, Jingjing;  Sun, Guangqiang;  He, Shen;  Luo, Zhiyu   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/05/22 Major depressive disorder  Peripheral changes  Gut microbiota  Immune phenotyping  Multiomics  Biomarkers   Discovery and Optimization of Novel Nonbile Acid FXR Agonists as Preclinical Candidates for the Treatment of Inflammatory Bowel Disease 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 7, 页码: 5642-5661 作者:  Li, Yuan;  Xu, Tingting;  Zhao, Yue;  Zhang, Hui;  Liu, Zesheng   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/05/07 Ecto-nucleotide pyrophosphatase/phosphodiesterase 1 inhibitors: Research progress and prospects 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 267, 页码: 13 作者:  Guan, Dezhong;  Fang, Lincheng;  Feng, Mingshun;  Guo, Shi;  Xie, Lingfeng   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/05/07 ENPP1 inhibitors  cGAS-STING pathway  2 ', 3 '-cGAMP  Tumor immunotherapy   Structure-based discovery of a new series of nucleoside-derived ring-opening PRMT5 inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 267, 页码: 19 作者:  Chen, Yuting;  Wang, Zekun;  Zhang, Junjie;  Shi, Qiongyu;  Yang, Hong   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/05/07 PRMT5  Nucleoside derivatives  Methyltransferases  Structure -activity relationship   Molecular recognition and activation of the prostacyclin receptor by anti-pulmonary arterial hypertension drugs 期刊论文  OAI收割 SCIENCE ADVANCES, 2024, 卷号: 10, 期号: 6, 页码: 11 作者:  Wang, James Jiqi;  Jin, Sanshan;  Zhang, Heng;  Xu, Youwei;  Hu, Wen   |  收藏  |  浏览/下载：0/0  |  提交时间：2024/05/07 Transfer learning enhanced graph neural network for aldehyde oxidase metabolism prediction and its experimental application 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 2, 页码: 623-634 作者:  Xiong, Jiacheng;  Cui, Rongrong;  Li, Zhaojun;  Zhang, Wei;  Zhang, Runze   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/05/07 Drug metabolism  Aldehyde oxidase  Transfer learning  Graph neural network  Kinase inhibitor   Visible-Light-Induced Decarboxylative Aminosulfonylation of (Hetero)aryl Carboxylic Oxime Esters 期刊论文  OAI收割 ORGANIC LETTERS, 2024, 卷号: 26, 期号: 3, 页码: 713-718 作者:  Zhuang, Zhen;  Sun, Yuting;  Zhong, Yuanchen;  He, Qian;  Zhang, Xiaofei   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/02/27 Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRASG12D 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1147-1167 作者:  Zhou, Chuan;  Fan, Zisheng;  Gu, Yuejiao;  Ge, Zhiming;  Tao, Zhaofan   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/02/27 JE-133 Suppresses LPS-Induced Neuroinflammation Associated with the Regulation of JAK/STAT and Nrf2 Signaling Pathways 期刊论文  OAI收割 ACS CHEMICAL NEUROSCIENCE, 2024, 卷号: 15, 期号: 2, 页码: 258-267 作者:  Tao, Lingxue;  Yu, Weichen;  Liu, Ziyi;  Zhao, Danfeng;  Lin, Sijin   |  收藏  |  浏览/下载：24/0  |  提交时间：2024/02/27 neuroinflammation  microglia  LPS  JAK/STAT  Nrf2   The emergence of machine learning force fields in drug design 期刊论文  OAI收割 MEDICINAL RESEARCH REVIEWS, 2024, 页码: 36 作者:  Chen, Mingan;  Jiang, Xinyu;  Zhang, Lehan;  Chen, Xiaoxu;  Wen, Yiming   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/02/19 computational chemistry  drug design  force field  machine learning  molecular modeling