中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [136]
上海光学精密机械研... [35]
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期刊论文 [176]
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浏览/检索结果:
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Neuronal CCL2 responds to hyperglycaemia and contributes to anxiety disorders in the context of diabetes
期刊论文
OAI收割
NATURE METABOLISM, 2025, 卷号: 7, 期号: 5, 页码: 39
作者:
Pan, Kaijun
;
Gao, Yanan
;
Zong, Haichao
;
Zhang, Yongmei
;
Qi, Yingbei
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/06/23
Structural basis of the cysteinyl leukotriene receptor type 2 activation by LTD4
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2025, 卷号: 122, 期号: 15, 页码: 9
作者:
Jiang, Mengting
;
Xu, Youwei
;
Luan, Xiaodong
;
Wu, Kai
;
Li, Zhen
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/06/23
G protein-coupled receptor
cryo-electron microscopy
cysteinyl leukotriene receptor2
activation mechanism
G alpha q protein coupling
Catalytic System-Controlled [4+1] and [4+2] Annulation for the Construction of Pyrazolo[1,2-
a
]indazoles and Pyrazolo[1,2-
a
]cinnolines from Pyrazolidinones and Diazo Indandiones
期刊论文
OAI收割
JOURNAL OF ORGANIC CHEMISTRY, 2025, 卷号: 90, 期号: 16, 页码: 5419-5434
作者:
Xiao, Qiannan
;
Hu, Shulei
;
Fang, Feifei
;
Yan, Mengdi
;
Zhang, Shurui
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/06/23
Dynamic Cap-Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease
期刊论文
OAI收割
ADVANCED SCIENCE, 2025, 页码: 13
作者:
Su, Haixia
;
Wu, Guoqing
;
Xiong, Muya
;
Wang, Yuhang
;
Cao, Junyuan
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/05/27
covalent inhibitors
I7L protease
monkeypox virus
protein structures
substrate proteolysis
Molecular mechanisms of urate transport by the native human URAT1 and its inhibition by anti-gout drugs
期刊论文
OAI收割
CELL DISCOVERY, 2025, 卷号: 11, 期号: 1, 页码: 12
作者:
Wu, Canrong
;
Zhang, Chao
;
Jin, Sanshan
;
Wang, James Jiqi
;
Dai, Antao
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/05/27
Recent advances in targeted degradation in the RAS pathway
期刊论文
OAI收割
FUTURE MEDICINAL CHEMISTRY, 2025, 卷号: 17, 期号: 6, 页码: 693-708
作者:
Ge, Zhiming
;
Fan, Zisheng
;
He, Wei
;
Zhou, Guizhen
;
Zhou, Yidi
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/04/24
RAS
cancer
mutation
degrader
PROTAC
Time-Dependent Regulation of Sleep-Wakefulness and Electroencephalographic Characteristics by Spontaneous Running in Male Mice
期刊论文
OAI收割
JOURNAL OF SLEEP RESEARCH, 2025, 页码: 16
作者:
Zhou, Wufang
;
Zhou, Jialin
;
Lu, Qianyu
;
Wang, Long
;
Liang, Yutao
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/05/27
delta power
spontaneous running
theta wave
voluntary exercise
"3D channel maze" to control drug release from multiple unit tablets
期刊论文
OAI收割
JOURNAL OF CONTROLLED RELEASE, 2025, 卷号: 378, 页码: 236-246
作者:
Xu, Huipeng
;
Zhang, Liu
;
Fang, Longwei
;
He, Dunwei
;
York, Peter
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/04/01
Controlled release
Channel maze
Theophylline
Three dimension
Synchrotron radiation
A prodrug nanodevice co-delivering docetaxel and ROR1 siRNA for enhanced triple negative breast cancer therapy
期刊论文
OAI收割
ACTA BIOMATERIALIA, 2025, 卷号: 193, 页码: 498-513
作者:
Yin, Lixuan
;
Fu, Zirang
;
Wang, Mengmeng
;
Liu, Bo
;
Sun, Xujie
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2025/04/01
Triple-negative breast cancer
Docetaxel
Prodrug nanoparticle
ROR1 siRNA
pH responsive
Exploratory research on the effective chemical basis of tanreqing injection for treating acute lung injury: In vivo, in vitro and in silico
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2025, 卷号: 337, 页码: 11
作者:
Tang, Bixi
;
Xie, Like
;
Wang, Yangyang
;
Shi, Yulong
;
Kan, Weijuan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/11/26
Lung first-pass effect
Tanreqing injection
Pharmacokinetics
Sepsis-associated acute lung injury
Acute respiratory distress syndrome