机构

• 上海药物研究所 [13]

采集方式

• OAI收割 [13]

内容类型

• 期刊论文 [13]

发表日期

• 2023 [6]
• 2022 [2]
• 2021 [1]
• 2020 [4]

学科主题

筛选

浏览/检索结果: 共13条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of novel cGAS inhibitors based on natural flavonoids 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 140, 页码: 14 作者:  Li, Jiameng;  Xiong, Muya;  Liu, Jiayuan;  Zhang, Fengping;  Li, Minjun   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/08 Cyclic GMP-AMP synthase  Inhibitor  Flavonoids  Crystal structure  Virtual screening   Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15 作者:  Jiang, Xiangrui;  Su, Haixia;  Shang, Weijuan;  Zhou, Feng;  Zhang, Yan   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/03/25 Multi-omics for COVID-19: driving development of therapeutics and vaccines 期刊论文  OAI收割 NATIONAL SCIENCE REVIEW, 2023, 卷号: 10, 期号: 9, 页码: 30 作者:  Guo, Mengyu;  Xiong, Muya   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/19 COVID-19  SARS-CoV-2  multi-omics  antibodies  small-molecule drugs  vaccines   Discovery of Novel 5,6-Dihydro-1,2,4-triazine Derivatives as Efficacious Glucagon-Like Peptide-1 Receptor Agonists 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 23 作者:  Chen, Lili;  Yun, Ying;  Guo, Shimeng;  Wang, Xiaoyan;  Xiong, Muya   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/10/17 Structure-Based Design of Potent Peptidomimetic Inhibitors Covalently Targeting SARS-CoV-2 Papain-like Protease 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 10, 页码: 15 作者:  Wang, Qian;  Chen, Guofeng;  He, Jian;  Li, Jiameng;  Xiong, Muya   |  收藏  |  浏览/下载：18/0  |  提交时间：2023/10/17 SARS-CoV-2  papain-like protease  covalent inhibitor  co-crystal structure  in vitro assay   Unraveling the catalytic mechanism of SARS-CoV-2 papain-like protease with allosteric modulation of C270 mutation using multiscale computational approaches 期刊论文  OAI收割 CHEMICAL SCIENCE, 2023, 卷号: 14, 期号: 18, 页码: 4681-4696 作者:  Shao, Qiang;  Xiong, Muya;  Li, Jiameng;  Hu, Hangchen;  Su, Haixia   |  收藏  |  浏览/下载：0/0  |  提交时间：2024/03/27 Bispecific prodrug nanoparticles circumventing multiple immune resistance mechanisms for promoting cancer immunotherapy 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 6, 页码: 2695-2709 作者:  Ye, Jiayi;  Hou, Bo;  Chen, Fangmin;  Zhang, Shunan;  Xiong, Muya   |  收藏  |  浏览/下载：11/0  |  提交时间：2024/03/21 Immunotherapy  Prodrug nanoparticles  Immune evasion  Immunogenic cell death  Tumor microenvironment   In silico screening-based discovery of novel covalent inhibitors of the SARS-CoV-2 3CL protease 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 231, 页码: 8 作者:  Xiong, Muya;  Nie, Tianqing;  Shao, Qiang;  Li, Minjun;  Su, Haixia   |  收藏  |  浏览/下载：21/0  |  提交时间：2022/06/15 SARS-CoV-2 3C-Like protease  Covalent inhibitor  Virtual screening  Crystal structure   What coronavirus 3C-like protease tells us: From structure, substrate selectivity, to inhibitor design 期刊论文  OAI收割 MEDICINAL RESEARCH REVIEWS, 2021, 页码: 34 作者:     |  收藏  |  浏览/下载：18/0  |  提交时间：2021/05/24 3C-like protease  binding modes  coronavirus  inhibitors  structure and function   USP28 and USP25 are downregulated by Vismodegib in vitro and in colorectal cancer cell lines 期刊论文  OAI收割 FEBS JOURNAL, 2020, 页码: 18 作者:  Wang, Hui;  Meng, Qian;  Ding, Yiluan;  Xiong, Muya;  Zhu, Mengying   |  收藏  |  浏览/下载：41/0  |  提交时间：2020/12/24 colorectal cancer  HDX-MS  inhibitor  USP25  USP28  Vismodegib