中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海生物化学与细胞... [58]
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期刊论文 [110]
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共114条,第1-10条
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Targeted Degradation of SOS1 Exhibits Potent Anticancer Activity and Overcomes Resistance in KRAS-Mutant Tumors and BCR-ABL-Positive Leukemia
期刊论文
OAI收割
CANCER RESEARCH, 2025, 卷号: 85, 期号: 1, 页码: 101-117
作者:
Luo, Ziwei
;
Lin, Chencen
;
Yu, Chuwei
;
Yuan, Changxian
;
Wu, Wenyong
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/02/28
Identification of USP2 as a novel target to induce degradation of KRAS in myeloma cells
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 12, 页码: 5235-5248
作者:
Wang, Yingying
;
Zhang, Youping
;
Luo, Hao
;
Wei, Wei
;
Liu, Wanting
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/04/01
Ubiquitin-specific protease 2
KRAS
Gambogic acid
Multiple myeloma
Degradation
Ubiquitination
Allosteric pocket
Deubiquitination
Carrier-phonon decoupling in perovskite thermoelectrics via entropy engineering
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2024, 卷号: 15
作者:
Zheng, Yunpeng
;
Zhang, Qinghua
;
Shi, Caijuan
;
Zhou, Zhifang
;
Lu, Yang
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/11/20
Targeting ST8SIA6-AS1 counteracts KRAS
G12C
inhibitor resistance through abolishing the reciprocal activation of PLK1/c-Myc signaling
期刊论文
OAI收割
EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2023, 卷号: 12, 期号: 1, 页码: 22
作者:
Wang, Yafang
;
Yao, Mingyue
;
Li, Cheng
;
Yang, Kexin
;
Qin, Xiaolong
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2024/01/26
KRAS(G12C)
c-Myc
PLK1
LncRNA
ST8SIA6-AS1
Drug resistance
Discovery of zolinium TSG1180 as a novel agonist of transgelin-2 for treating asthma
期刊论文
OAI收割
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, 卷号: 167, 页码: 115556
作者:
Yuan, Hong-Kai
;
Li, Bo
;
Wu, Leyun
;
Wang, Xue-Ling
;
Lv, Zhi-Ying
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/03/26
Active learning
Consensus labelling
Eye irritation
Serious eye damage
Structural alerts
Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in cancer
期刊论文
OAI收割
CANCER CELL, 2023, 卷号: 41, 期号: 7, 页码: 1345-+
作者:
Wang, Hanling
;
Li, Ni
;
Liu, Qiuli
;
Guo, Jiacheng
;
Pan, Qiang
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2023/10/17
Theoretical Investigation of Spectroscopic Properties of the Alkaline-Earth-Metal Monohydrides toward Laser Cooling and Magneto-Optical Trapping
期刊论文
OAI收割
ACS OMEGA, 2023, 卷号: 8, 期号: 22, 页码: 19391-19401
作者:
Pang, Renjun
;
Yin, Junhao
;
Wang, Yueyang
;
Lin, Qinning
;
Wang, Zesen
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/11/14
Molecular dynamics study on the behavior and binding mechanism of target protein Transgelin-2 with its agonist TSG12 for anti-asthma drug discovery
期刊论文
OAI收割
COMPUTERS IN BIOLOGY AND MEDICINE, 2023, 卷号: 153, 页码: 7
作者:
Wu, Leyun
;
Wang, Guangpu
;
Zhou, Liping
;
Mo, Mengxia
;
Shi, Yulong
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2023/04/10
Pharmaceutical sciences
Molecular dynamics simulation
Free energy calculation
Asthma
Target protein
Transgelin-2
Agonist
ARID1A loss induces polymorphonuclear myeloid-derived suppressor cell chemotaxis and promotes prostate cancer progression
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 20
作者:
Li, Ni
;
Liu, Qiuli
;
Han, Ying
;
Pei, Siyu
;
Cheng, Bisheng
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2023/04/10
p Proteogenomic characterization identifies clinically relevant subgroups of intrahepatic cholangiocarcinoma
期刊论文
OAI收割
CANCER CELL, 2022, 卷号: 40, 期号: 1, 页码: 70-+
作者:
Dong, Liangqing
;
Lu, Dayun
;
Chen, Ran
;
Lin, Youpei
;
Zhu, Hongwen
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2022/06/15