中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [5]
长春应用化学研究所 [5]
中国科学院大学 [4]
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期刊论文 [31]
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2023 [3]
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Discovery of Potent and Selective CB2 Agonists Utilizing a Function-Based Computational Screening Protocol
期刊论文
OAI收割
ACS CHEMICAL NEUROSCIENCE, 2023, 卷号: 14, 期号: 21, 页码: 3941-3958
作者:
Ge, Haixia
;
Ji, Beihong
;
Fang, Jiahui
;
Wang, Jiayang
;
Li, Jing
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/12/11
function-based ligand design
receptor-ligandbinding profile
CB1/CB2
structure-activityrelationship
Discovery and Mechanism Study of SARS-CoV-2 3C-like Protease Inhibitors with a New Reactive Group
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 18
作者:
Ren, Pengxuan
;
Li, Hui
;
Nie, Tianqing
;
Jian, Xiaoqin
;
Yu, Changyue
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/10/17
Discovery, synthesis and mechanism study of 2,3,5-substituted [1,2,4]-thiadiazoles as covalent inhibitors targeting 3C-Like protease of SARS-CoV-2
期刊论文
OAI收割
European journal of medicinal chemistry, 2023, 卷号: 249, 页码: 115129
作者:
Ren, Pengxuan
;
Yu, Changyue
;
Zhang, Ruxue
;
Nie, Tianqing
;
Hu, Qiaoyu
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2024/03/26
Discovery of 10H-Benzo[b]pyrido[2,3-e][1,4]oxazine AXL Inhibitors via Structure-Based Drug Design Targeting c-Met Kinase
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 15
作者:
Zhan, Zhengsheng
;
Ji, Yinchun
;
Su, Haixia
;
Fang, Chen
;
Peng, Xia
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2023/04/10
Copula-based non-stationarity detection of the precipitation-temperature dependency structure dynamics and possible driving mechanism
期刊论文
OAI收割
ATMOSPHERIC RESEARCH, 2021, 卷号: 249, 页码: 15
作者:
Dong, Haixia
;
Huang, Shengzhi
;
Fang, Wei
;
Leng, Guoyong
;
Wang, Hao
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2021/06/10
Precipitation-temperature dependency structure
Non-stationarity
Copula-based Likelihood-ratio method
Double mass curve
Teleconnection factors
Driving mechanism
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
期刊论文
OAI收割
AUTOPHAGY, 2021, 卷号: 17
作者:
Klionsky, Daniel J.
;
Abdel-Aziz, Amal Kamal
;
Abdelfatah, Sara
;
Abdellatif, Mahmoud
;
Abdoli, Asghar
  |  
收藏
  |  
浏览/下载:319/0
  |  
提交时间:2021/05/31
Autophagosome
cancer
flux
LC3
lysosome
macroautophagy
neurodegeneration
phagophore
stress
vacuole
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease
期刊论文
OAI收割
SCIENCE, 2020, 卷号: 368, 期号: 6497, 页码: 1331-+
作者:
Dai, Wenhao
;
Zhang, Bing
;
Jiang, Xia-Ming
;
Su, Haixia
;
Li, Jian
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收藏
  |  
浏览/下载:55/0
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提交时间:2020/12/24
Development and External Validation of Radiomics Approach for Nuclear Grading in Clear Cell Renal Cell Carcinoma
期刊论文
OAI收割
ANNALS OF SURGICAL ONCOLOGY, 2020, 页码: 9
作者:
Zhou, Hongyu
;
Mao, Haixia
;
Dong, Di
;
Fang, Mengjie
;
Gu, Dongsheng
  |  
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2020/06/22
Soil enzyme kinetics indicate ecotoxicity of long-term arsenic pollution in the soil at field scale
期刊论文
OAI收割
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 191, 页码: 8
作者:
Wang, Ziquan
;
Tian, Haixia
;
Lei, Mei
;
Megharaj, Mallavarapu
;
Tan, Xiangping
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/05/19
Field soil pollution
Catalytic efficiency
Risk assessment
Bioindicator
Ecological dose
Genomes of the Banyan Tree and Pollinator Wasp Provide Insights into Fig-Wasp Coevolution
期刊论文
OAI收割
CELL, 2020, 卷号: 183, 期号: 4, 页码: 875_+
作者:
Zhang, Xingtan
;
Wang, Gang
;
Zhang, Shengcheng
;
Chen, Shuai
;
Wang, Yibin
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2020/12/31