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Chinese Academy of Sciences Institutional Repositories Grid
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Pharmacokinetics, mass balance, and metabolism of [
14
C]PLB1004, a selective and irreversible EGFR-TKI in humans
期刊论文
OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2025, 卷号: 95, 期号: 1, 页码: 14
作者:
Liu, Donghui
;
Li, Qian
;
Yan, Shu
;
Zhang, Xinyue
;
Li, Weiqiang
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2025/04/01
PLB1004
[C-14]PLB1004
Radioactivity
Mass balance
EGFR-TKI
A spatio-temporal fusion method for non-destructive testing using infrared thermography
期刊论文
OAI收割
OPTICS AND LASERS IN ENGINEERING, 2025, 卷号: 194, 页码: 14
作者:
Huang XF(黄晓芙)
;
Hou XY(侯星宇)
;
Wang, Puxiang
;
Zhao, Dong
;
Zhao, Jian
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/08/18
Infrared thermography
Spatio-temporal fusion thermography
Linear laser thermography
Optical flow method
Surface defects
Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17
作者:
Mo, Jun
;
Wang, Yuxian
;
Pan, Youlu
;
Xiao, Qitao
;
Zhao, Jinyi
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/08/20
Menin
High binding affinity
Anti-proliferation activity
AML
Transboundary impacts of microplastics within planetary boundaries: Regulation and responses of soil-plant systems under climate change
期刊论文
OAI收割
ENVIRONMENTAL RESEARCH, 2025, 卷号: 282, 页码: 122080
作者:
Lu, Gaoyu
;
Wang, Zhirong
;
Wang, Junbang
;
Zhang, Xiujuan
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/07/18
Microplastics
Climate change
Soil-plant systems
Planetary boundaries
Ecotoxicity
Kadcoccinoids A-K, triterpenoids from
Kadsura coccinea
with PCSK9 expression inhibitory activities
期刊论文
OAI收割
PHYTOCHEMISTRY, 2025, 卷号: 238, 页码: 13
作者:
Duan, Yelin
;
Chen, Tong
;
Guo, Pengju
;
Li, Chenyue
;
Chen, Yihan
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
Kadsura coccinea
Schisandraceae
Lanostane-type triterpenoids
Protostane-type triterpenoids
PCSK9
The Intermediate-mass Black Hole Reverberation Mapping Project: First Detection of Mid-infrared Lags in Prototypical Intermediate-mass Black Holes in NGC 4395 and POX 52
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2025, 卷号: 989, 期号: 2
作者:
Sun, Jingbo
;
Guo, Hengxiao
;
Zuo, Wenwen
;
Lira, Paulina
;
Gu, Minfeng
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/08/25
Advancing the mechanical performance of chemically complex alloys through strategically engineered bamboo-inspired multi-stage heterostructures
期刊论文
OAI收割
COMPOSITES PART B-ENGINEERING, 2025, 卷号: 302, 页码: 22
作者:
Cui, Zhenlu
;
Si, Dekun
;
Zhang, Jilei
;
Gao, Qingwei
;
Gong, Jianhong
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2025/06/23
Chemically complex alloys
Heterogeneous microstructure
Hierarchical precipitates
Mechanical properties
Strengthening mechanisms
Discovery of novel imidazo[2,1-b][1,3,4]thiadiazole analogs as fluorescent SHP2 inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 163, 页码: 10
作者:
Zhang, Chun
;
Yan, Xue
;
Gao, Li-Xin
;
Cao, Zi-Tong
;
Cao, Qing
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/08/20
Imidazo[2,1-b][1,3,4]thiadiazole
Inhibitory activities
Fluorescence imaging
Zebrafish
SHP2
Ultrasensitive magnetic nanomechanical biosensors for simultaneous detection of multiple cardiovascular disease biomarkers in a single blood drop
期刊论文
OAI收割
BIOSENSORS & BIOELECTRONICS, 2025, 卷号: 280, 页码: 10
作者:
Chen, Qiubo
;
Zhang, Lin
;
Qiao, Zihan
;
Yang, Yipeng
;
Wu, Wenjie
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2025/06/23
Cardiovascular diseases (CVD)
Early diagnosis
Ultrasensitive sensor
Magnetic force
Microcantilever array
A drop of blood
Nanomechanics
Benzothiazole amide analogues as antagonists of TRPC 6 channels: A therapeutic approach for kidney fibrosis
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 16
作者:
Ren, Chunlin
;
Xu, Qiding
;
Luo, Qiusi
;
Qiao, Xue
;
Ding, Taotao
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2025/06/23
Transient receptor potential canonical 6
channels
Antagonist
Renal fibrosis
Benzothiazole derivatives
Unilateral ureteral obstruction