中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共233条,第1-10条 帮助

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Discovery of CZL-046 with an (S)-3-Fluoropyrrolidin-2-one Scaffold as a p300 Bromodomain Inhibitor for the Treatment of Multiple Myeloma 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 20, 页码: 18606-18628
作者:  
Chen, Zonglong;  Yang, Hong;  Zhang, Yan;  Lyu, Xiaodong;  Shi, Qiongyu
  |  收藏  |  浏览/下载:8/0  |  提交时间:2024/11/05
Development of ketalized unsaturated saccharides as multifunctional cysteine-targeting covalent warheads 期刊论文  OAI收割
COMMUNICATIONS CHEMISTRY, 2024, 卷号: 7, 期号: 1, 页码: 10
作者:  
Dong, Sanfeng;  Huang, Hui;  Li, Jintian;  Li, Xiaomei;  Bunu, Samuel Jacob
  |  收藏  |  浏览/下载:12/0  |  提交时间:2024/10/21
Vertical variations of bacteriohopanepolyols near the Changjiang Estuary waters: Implications for marine hypoxia and bacterial activities 期刊论文  OAI收割
CHEMICAL GEOLOGY, 2024, 卷号: 651, 页码: 14
作者:  
Yin, Meiling;  Duan, Liqin;  Song, Jinming;  Kan, Jiawei;  Yuan, Huamao
  |  收藏  |  浏览/下载:23/0  |  提交时间:2024/06/04
Discovery of Novel PROTAC Degraders of p300/CBP as Potential Therapeutics for Hepatocellular Carcinoma 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2466-2486
作者:  
Chang, Qi;  Li, Jiayi;  Deng, Yue;  Zhou, Ruilin;  Wang, Bingwei
  |  收藏  |  浏览/下载:35/0  |  提交时间:2024/03/25
Design and synthesis of cantharidin derivative DCZ5418 as a TRIP13 inhibitor with anti-multiple myeloma activity in vitro and in vivo 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 98, 页码: 7
作者:  
Dong, Sanfeng;  Hu, Ke;  Shi, Yulong;  Wang, Guanli;  Yu, Dandan
  |  收藏  |  浏览/下载:26/0  |  提交时间:2024/02/19
Synthesis, evaluation and molecular dynamics study of human toll-like receptor 2/6 specific monoacyl lipopeptides as candidate immunostimulants 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 141, 页码: 17
作者:  
Zhu, Yueyue;  Liu, Bo;  Chen, Zonglong;  Wang, Xianyang;  Wang, Yujie
  |  收藏  |  浏览/下载:26/0  |  提交时间:2023/12/08
Design, synthesis of auristatins-glucuronide conjugates targeting the β-glucuronidase in tumor microenvironment 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 95, 页码: 5
作者:  
Wang, Yujie;  Xu, Keshi;  Liu, Hongchun
  |  收藏  |  浏览/下载:20/0  |  提交时间:2023/12/19
The first record of Lower Cretaceous theropod tracks in Turpan-Hami Basin, Xinjiang, northwestern China 期刊论文  OAI收割
HISTORICAL BIOLOGY, 2023, 页码: 6
作者:  
Li, Yang;  Jiang, Shunxing;  Yan, Feng;  Ma, Yingxia;  Wang, Xiaolin
  |  收藏  |  浏览/下载:32/0  |  提交时间:2023/11/02
Geology, geochronology, and geochemistry of the Gaojiabang tungsten-molybdenum deposit, Anhui Province, Southeast China 期刊论文  OAI收割
ORE GEOLOGY REVIEWS, 2023, 卷号: 157, 页码: 28
作者:  
Zheng, Fangshun;  Qin, Kezhang;  Cook, Nigel J.;  Li, Guangming;  Ciobanu, Cristiana L.
  |  收藏  |  浏览/下载:24/0  |  提交时间:2023/12/29
Optimization of potent, selective and orally bioavailable biphenyl scaffold as FABP4 inhibitors for anti-inflammation 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 253, 页码: 16
作者:  
He, Yulong;  Li, Shunyi;  Zhu, Yueyue;  Wang, Yujie;  Chen, Yuqi
  |  收藏  |  浏览/下载:78/0  |  提交时间:2023/10/17