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Glabridin inhibits migration and invasion by transcriptional inhibition of matrix metalloproteinase-9 through modulation of NF-B and AP-1 activity in human liver cancer cells lines
期刊论文
OAI收割
出版物, 3111, 期号: 0, 页码: 1—28
作者:
Ming-Ju Hsieh
;
Chiao-Wen Lin
;
Shun-Fa Yang
;
Mu-Kuan Chen
;
Hui-Ling Chiou
  |  
收藏
  |  
浏览/下载:419/0
  |  
提交时间:2017/07/24
Glabridin
Migration
Invasion
Matrix Metalloproteinase-9
Hepatoma
Pharmacokinetics, mass balance, and metabolism of [
14
C]FCN-437c, a selective and potent CDK4/6 inhibitor in humans
期刊论文
OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2025, 卷号: 95, 期号: 1, 页码: 12
作者:
Gao, Lei
;
Ma, Sheng
;
Yan, Shu
;
Zhang, Hua
;
Tian, Ling
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/07/25
FCN-437c
CDK4/6 inhibitor
Mass balance
Radiopharmacokinetics
Drug metabolism
Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17
作者:
Mo, Jun
;
Wang, Yuxian
;
Pan, Youlu
;
Xiao, Qitao
;
Zhao, Jinyi
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/08/20
Menin
High binding affinity
Anti-proliferation activity
AML
Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CL
pro
inhibitors against SARS-CoV-2
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 11
作者:
Guma, Samuel Desta
;
Song, Kang
;
Sun, Haiguo
;
Yang, Lei
;
Zhou, Zhaoyin
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
SARS-CoV-2
3CL(pro) inhibitors
Thioamide derivatives
Spiropyrrolidine derivatives
Nirmatrelvir
HCoV-OC43
Antiviral
Metabolic stability
Structural optimization of phthalazine derivatives for anti-HBV activities to improve oral bioavailability
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 10
作者:
Yang, Yurong
;
Xiao, Fuling
;
Zuo, Jianping
;
Yang, Li
;
Hu, Youhong
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
HBV
Capsid assembly modulators
Structural optimization
Oxidative metabolism
Interactive effects of nitrite and bifenthrin on bioaccumulation, oxidative stress and immune responses of
Haliotis
discus
hannai
期刊论文
OAI收割
AQUATIC TOXICOLOGY, 2025, 卷号: 287, 页码: 10
作者:
Chen, Hao
;
Wu, Guiqing
;
Jiao, Chunli
;
Chen, Lizhu
;
Sun, Chunxiao
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/10/14
Haliotis discus hannai
Nitrite
Bifenthrin
Transcriptomics
Immune function
Phenanthrenoid monomers and dimers from
Juncus
alatus:
Isolation, structural characterization, and anti-inflammatory potential
期刊论文
OAI收割
PHYTOCHEMISTRY, 2025, 卷号: 236, 页码: 15
作者:
Deng, Jingyi
;
Ke, Chang-Qiang
;
Feng, Zheling
;
Tang, Chunping
;
Ye, Yang
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2025/06/23
Juncus alatus franch. et sav.
Juncaceae
Alatusins A -G
Phenanthrenes
10-Dihydrophenanthrene
Phenanthrene dimers
Anti-inflammatory activity
Immunosuppressive nitrogen-containing triterpenoid saponins from
Mussaenda
erosa
and the therapeutic efficacy of heinsiagenin A in a murine lupus erythematosus model
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 163, 页码: 11
作者:
Xu, Yidan
;
Xiang, Mai
;
Chang, Yuan
;
Chen, Zhenhua
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
Mussaenda erosa
Nitrogen-containing triterpenoid saponins
Immunosuppressive activity
Autoimmune diseases
Heinsiagenin A
A reliable lithospheric thermal structure model of the South Yellow Sea in East Asian continental margin based on radiogenic heat production measurements
期刊论文
OAI收割
MARINE AND PETROLEUM GEOLOGY, 2025, 卷号: 178, 页码: 12
作者:
Guo, Xingwei
;
Pang, Yumao
;
Shi, Xiaobin
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2025/07/11
South Yellow Sea
East Asian continental margin
Lithospheric heat production
Surface heat flow
Geodynamics
Ultrasensitive magnetic nanomechanical biosensors for simultaneous detection of multiple cardiovascular disease biomarkers in a single blood drop
期刊论文
OAI收割
BIOSENSORS & BIOELECTRONICS, 2025, 卷号: 280, 页码: 10
作者:
Chen, Qiubo
;
Zhang, Lin
;
Qiao, Zihan
;
Yang, Yipeng
;
Wu, Wenjie
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2025/06/23
Cardiovascular diseases (CVD)
Early diagnosis
Ultrasensitive sensor
Magnetic force
Microcantilever array
A drop of blood
Nanomechanics