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Chinese Academy of Sciences Institutional Repositories Grid
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Glabridin inhibits migration and invasion by transcriptional inhibition of matrix metalloproteinase-9 through modulation of NF-B and AP-1 activity in human liver cancer cells lines
期刊论文
OAI收割
出版物, 3111, 期号: 0, 页码: 1—28
作者:
Ming-Ju Hsieh
;
Chiao-Wen Lin
;
Shun-Fa Yang
;
Mu-Kuan Chen
;
Hui-Ling Chiou
  |  
收藏
  |  
浏览/下载:418/0
  |  
提交时间:2017/07/24
Glabridin
Migration
Invasion
Matrix Metalloproteinase-9
Hepatoma
Pharmacokinetics, mass balance, and metabolism of [
14
C]FCN-437c, a selective and potent CDK4/6 inhibitor in humans
期刊论文
OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2025, 卷号: 95, 期号: 1, 页码: 12
作者:
Gao, Lei
;
Ma, Sheng
;
Yan, Shu
;
Zhang, Hua
;
Tian, Ling
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2025/07/25
FCN-437c
CDK4/6 inhibitor
Mass balance
Radiopharmacokinetics
Drug metabolism
Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17
作者:
Mo, Jun
;
Wang, Yuxian
;
Pan, Youlu
;
Xiao, Qitao
;
Zhao, Jinyi
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/08/20
Menin
High binding affinity
Anti-proliferation activity
AML
Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CL
pro
inhibitors against SARS-CoV-2
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 11
作者:
Guma, Samuel Desta
;
Song, Kang
;
Sun, Haiguo
;
Yang, Lei
;
Zhou, Zhaoyin
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
SARS-CoV-2
3CL(pro) inhibitors
Thioamide derivatives
Spiropyrrolidine derivatives
Nirmatrelvir
HCoV-OC43
Antiviral
Metabolic stability
Structural optimization of phthalazine derivatives for anti-HBV activities to improve oral bioavailability
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 10
作者:
Yang, Yurong
;
Xiao, Fuling
;
Zuo, Jianping
;
Yang, Li
;
Hu, Youhong
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
HBV
Capsid assembly modulators
Structural optimization
Oxidative metabolism
Phenanthrenoid monomers and dimers from
Juncus
alatus:
Isolation, structural characterization, and anti-inflammatory potential
期刊论文
OAI收割
PHYTOCHEMISTRY, 2025, 卷号: 236, 页码: 15
作者:
Deng, Jingyi
;
Ke, Chang-Qiang
;
Feng, Zheling
;
Tang, Chunping
;
Ye, Yang
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2025/06/23
Juncus alatus franch. et sav.
Juncaceae
Alatusins A -G
Phenanthrenes
10-Dihydrophenanthrene
Phenanthrene dimers
Anti-inflammatory activity
A reliable lithospheric thermal structure model of the South Yellow Sea in East Asian continental margin based on radiogenic heat production measurements
期刊论文
OAI收割
MARINE AND PETROLEUM GEOLOGY, 2025, 卷号: 178, 页码: 12
作者:
Guo, Xingwei
;
Pang, Yumao
;
Shi, Xiaobin
;
Yang, Xiaoqiu
;
Zhang, Xunhua
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2025/07/11
South Yellow Sea
East Asian continental margin
Lithospheric heat production
Surface heat flow
Geodynamics
Immunosuppressive nitrogen-containing triterpenoid saponins from
Mussaenda
erosa
and the therapeutic efficacy of heinsiagenin A in a murine lupus erythematosus model
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 163, 页码: 11
作者:
Xu, Yidan
;
Xiang, Mai
;
Chang, Yuan
;
Chen, Zhenhua
;
Zhang, Rujun
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Mussaenda erosa
Nitrogen-containing triterpenoid saponins
Immunosuppressive activity
Autoimmune diseases
Heinsiagenin A
Ultrasensitive magnetic nanomechanical biosensors for simultaneous detection of multiple cardiovascular disease biomarkers in a single blood drop
期刊论文
OAI收割
BIOSENSORS & BIOELECTRONICS, 2025, 卷号: 280, 页码: 10
作者:
Chen, Qiubo
;
Zhang, Lin
;
Qiao, Zihan
;
Yang, Yipeng
;
Wu, Wenjie
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2025/06/23
Cardiovascular diseases (CVD)
Early diagnosis
Ultrasensitive sensor
Magnetic force
Microcantilever array
A drop of blood
Nanomechanics
Study of ultra-high-energy gamma-ray source 1LHAASO J0056+6346u and its possible origins
期刊论文
OAI收割
SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2025, 卷号: 68, 期号: 7
作者:
Cao, Zhen
;
Aharonian, F.
;
Axikegu
;
Bai, Y. X.
;
Bao, Y. W.
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2025/06/10
gamma rays
cosmic rays
supernova remnant
young massive cluster
pulsar