机构

• 上海药物研究所 [16]
• 沈阳应用生态研究所 [8]
• 海洋研究所 [2]
• 烟台海岸带研究所 [2]
• 物理研究所 [1]
• 金属研究所 [1]
• 更多

采集方式

• OAI收割 [37]

内容类型

• 期刊论文 [36]
• CNKI期刊论文 [1]

发表日期

• 2025 [1]
• 2024 [4]
• 2023 [3]
• 2022 [2]
• 2021 [2]
• 2019 [3]
• 更多

学科主题

• Environmen... [1]
• Environmen... [1]
• 空间环境 [1]

筛选

浏览/检索结果: 共37条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 Structure-Based Discovery of a Series of Novel MAT2a Inhibitors 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2025, 页码: 5 作者:  Zhou, Yushan;  Wang, Li;  Ren, Ruyue;  Zhang, Junjie;  Huan, Xiajuan   |  收藏  |  浏览/下载：2/0  |  提交时间：2025/05/27 MAT2a  MTAP  Synthetic lethality  Allosteric inhibitor  Structure-activity relationship   Optimization and Biological Evaluation of Novel 1H-Pyrrolo[2,3-c]pyridin Derivatives as Potent and Reversible Lysine Specific Demethylase 1 Inhibitors for the Treatment of Acute Myelogenous Leukemia 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 24, 页码: 22080-22103 作者:  Jiang, Hong;  Li, Cong;  Li, Na;  Sheng, Li;  Wang, Jingkai   |  收藏  |  浏览/下载：14/0  |  提交时间：2025/01/14 Structural Basis of Main Proteases of Coronavirus Bound to Bofutrelvir 期刊论文  OAI收割 JOURNAL OF MOLECULAR BIOLOGY, 2024, 卷号: 436, 期号: 22, 页码: 16 作者:  Wang, Wei-wei;  Zeng, Pei;  Liu, Tongchao;  Zhou, Xue-lan;  Lin, Cheng   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/10/21 SARS-CoV-2  Coronavirus  Main protease  Mutants  Inhibitor   Design, synthesis, and biological evaluation of pyrido[2,3-d]pyrimidin-7 (8H)-one derivatives as potent USP1 inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 275, 页码: 18 作者:  Li, Hongrui;  Liu, Ben-Jin;  Xu, Jiahao;  Song, Shan-Shan;  Ba, Ruixian   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/08/22 USP1 inhibitor  Structure -activity relationships  Olaparib-resistant cell   Structure-based discovery of a new series of nucleoside-derived ring-opening PRMT5 inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 267, 页码: 19 作者:  Chen, Yuting;  Wang, Zekun;  Zhang, Junjie;  Shi, Qiongyu;  Yang, Hong   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/05/07 PRMT5  Nucleoside derivatives  Methyltransferases  Structure -activity relationship   Structure-based discovery of potent USP28 inhibitors derived from Vismodegib 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 15 作者:  Zhou, Di;  Xu, Zhuo;  Huang, Yaodong;  Wang, Hui;  Zhu, Xiaoli   |  收藏  |  浏览/下载：46/0  |  提交时间：2023/10/17 USP28  Structure-based  Vismodegib derivatives  Structure-activity relationships  c-Myc   Development of a series of quinazoline-2,5-diamine derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 248, 页码: 20 作者:  Shi, Huanyu;  Tang, Haotian;  Li, Yan;  Chen, Danqi;  Liu, Tongchao   |  收藏  |  浏览/下载：36/0  |  提交时间：2023/04/10 Cancer immunotherapy  SAR study  HPK1 inhibitors  Quinazoline-2  5-diamine  IL-2 production   Structure-activity relationship study of a series of nucleoside derivatives bearing sulfonamide scaffold as potent and selective PRMT5 inhibitors 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 130, 页码: 20 作者:  Chen, Yuting;  Shi, Qiongyu;  Yang, Hong;  Li, Jiayi;  Zhou, Kaixin   |  收藏  |  浏览/下载：43/0  |  提交时间：2023/04/10 Epigenetic  PRMT5 inhibitor  Nucleoside derivatives  Structure-activity Relationship Prodrug   Identification of 1H-pyrazolo[3,4-b]pyridine derivatives as novel and potent TBK1 inhibitors: design, synthesis, biological evaluation, and molecular docking study 期刊论文  OAI收割 JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1411-1425 作者:  Sun, Yin;  Tang, Haotian;  Wang, Xiaoyan;  Feng, Fang;  Fan, Tiantian   |  收藏  |  浏览/下载：63/0  |  提交时间：2022/08/16 TBK1 inhibitors  1H-pyrazolo[3  4-b]pyridine  structure-activity relationships (SARs)  immune response  cancer therapy   Structure-Based of a Series of NSD2-PWWP1 Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 13, 页码: 9459-9477 作者:  Li, Na;  Yang, Hong;  Liu, Ke;  Zhou, Liwei;  Huang, Yuting   |  收藏  |  浏览/下载：31/0  |  提交时间：2024/03/21 首页 上一页 1 2 3 4 下一页 末页