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浏览/检索结果: 共140条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序作者升序作者降序题名升序题名降序发表日期升序发表日期降序 Conformational restriction enables discovering a series of chroman derivatives as potent and selective NaV1.8 inhibitors with improved pharmacokinetic properties 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 293, 页码: 24 作者:  Li, Na;  Wang, Linlin;  Hu, Xinyuan;  Xu, Haiyan;  Yang, Bowen   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/08/20 Voltage-gated sodium channel 1.8  Conformational restriction  Pharmacokinetic  Structure-activity relationship  Analgesic   (+)-Borneol Enhances the Antiseizure Effects of Retigabine by both Pharmacokinetic and Pharmacodynamic Interaction 期刊论文  OAI收割 NEUROCHEMICAL RESEARCH, 2025, 卷号: 50, 期号: 3, 页码: 13 作者:  Xu, Haiyan;  Wu, Zhidan;  Wang, Pei;  Gong, Jili;  Qiu, Li   |  收藏  |  浏览/下载：28/0  |  提交时间：2025/06/23 Epilepsy  Retigabine  (+)-Borneol  Synergistic interaction  KCNQ channels   Structural Optimization of Next-Generation TRK Inhibitors against Acquired Drug Resistance Mutations for the Treatment of Solid Tumors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 11, 页码: 11484-11501 作者:  Xu, Zichao;  Liu, Yueling;  Wang, Peng;  Peng, Xia;  Cheng, Jiawei   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/08/20 O-PRESS: Boosting OCT axial resolution with Prior guidance, Recurrence, and Equivariant Self-Supervision 期刊论文  OAI收割 MEDICAL IMAGE ANALYSIS, 2025, 卷号: 99, 页码: 16 作者:  Li, Kaiyan;  Yang, Jingyuan;  Liang, Wenxuan;  Li, Xingde;  Zhang, Chenxi   |  收藏  |  浏览/下载：18/0  |  提交时间：2024/12/06 Retinal imaging  OCT image reconstruction  Resolution  Self-supervised learning  Prior guidance   Which riverine water quality parameters can be predicted by meteorologically-driven deep learning? 期刊论文  OAI收割 SCIENCE OF THE TOTAL ENVIRONMENT, 2024, 卷号: 946, 页码: 174357 作者:  Huang, Sheng;  Wang, Yueling;  Xia, Jun   |  收藏  |  浏览/下载：29/0  |  提交时间：2024/09/19 Water quality parameter  Deep learning  Meteorological condition  Extreme value  Climate change  Collective prediction   Pollution loads in the middle-lower Yangtze river by coupling water quality models with machine learning 期刊论文  OAI收割 WATER RESEARCH, 2024, 卷号: 263, 页码: 13 作者:  Huang, Sheng;  Xia, Jun;  Wang, Yueling;  Wang, Gangsheng;  She, Dunxian   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/11/28 Water quality model  Machine learning  Pollution loads  The Yangtze River  Anthropogenic activities  Gated recurrent unit   Water quality prediction based on sparse dataset using enhanced machine learning 期刊论文  OAI收割 ENVIRONMENTAL SCIENCE AND ECOTECHNOLOGY, 2024, 卷号: 20, 页码: 100402 作者:  Huang, Sheng;  Xia, Jun;  Wang, Yueling;  Lei, Jiarui;  Wang, Gangsheng   |  收藏  |  浏览/下载：30/0  |  提交时间：2024/06/17 Water quality modeling  Sparse measurement  River -lake confluence  Long short-term memory  Load estimator  Machine learning   Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses 期刊论文  OAI收割 NATURE CHEMICAL BIOLOGY, 2024, 页码: 29 作者:  Zhou, Xiaoyu;  Zhao, Cheng;  Xu, Haiyan;  Xu, Yixiang;  Zhan, Li   |  收藏  |  浏览/下载：58/0  |  提交时间：2024/03/25 基于Vine Copula的鄱阳湖流域近70a洪水空间分异规律 期刊论文  OAI收割 长江科学院院报, 2024, 卷号: N/A, 页码: 1-8 作者:  吴家璇;  胡实;  王月玲;  占车生   |  收藏  |  浏览/下载：47/0  |  提交时间：2024/02/04 多维联合分布  Vine Copula  洪水特征值  重现期  鄱阳湖流域   A coupled model applied to complex river-lake systems 期刊论文  OAI收割 HYDROLOGICAL SCIENCES JOURNAL, 2023, 卷号: N/A 作者:  Zhang, Qi;  Zhan, Chesheng;  Wang, Yueling;  Zhang, Haoyue;  Lin, Zhonghui   |  收藏  |  浏览/下载：33/0  |  提交时间：2024/01/04 coupled model  river-lake system  machine learning  hydrology  hydrodynamic model