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浏览/检索结果: 共32条，第1-10条 帮助

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Discovery of Novel PROTAC Degraders of p300/CBP as Potential Therapeutics for Hepatocellular Carcinoma 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2466-2486
作者:  Chang, Qi;  Li, Jiayi;  Deng, Yue;  Zhou, Ruilin;  Wang, Bingwei
  |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/25
Intelligent design and construction of novel APN-based theranostic probe driven by advanced computational methods 期刊论文  OAI收割
CHINESE CHEMICAL LETTERS, 2024, 卷号: 35, 期号: 2, 页码: 6
作者:  Zhu, Yingli;  Qian, Jie;  Yu, Kunqian;  Hou, Jing;  Ma, Yeshuo
  |  收藏  |  浏览/下载：12/0  |  提交时间：2024/01/26
Discovery of 10H-Benzo[b]pyrido[2,3-e][1,4]oxazine AXL Inhibitors via Structure-Based Drug Design Targeting c-Met Kinase 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 15
作者:  Zhan, Zhengsheng;  Ji, Yinchun;  Su, Haixia;  Fang, Chen;  Peng, Xia
  |  收藏  |  浏览/下载：30/0  |  提交时间：2023/04/10
Discovery of novel benzimidazole derivatives as potent p300 bromodomain inhibitors with anti-proliferative activity in multiple cancer cells 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 66, 页码: 16
作者:  Chen, Zonglong;  Li, Jiayi;  Yang, Hong;  He, Yulong;  Shi, Qiongyu
  |  收藏  |  浏览/下载：35/0  |  提交时间：2022/08/16
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:  Che, Jinxin;  Huang, Feng;  Zhang, Mengmeng;  Xu, Gaoya;  Qu, Bingxue
  |  收藏  |  浏览/下载：41/0  |  提交时间：2020/12/21
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:  Che, Jinxin;  Huang, Feng;  Zhang, Mengmeng;  Xu, Gaoya;  Qu, Bingxue
  |  收藏  |  浏览/下载：26/0  |  提交时间：2020/12/21
Structural optimization and neurotrophic activity evaluation of neurotrophic gentiside derivatives 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 22, 页码: 6
作者:  Wang, Zhenkang;  Ma, Chunhua;  Wang, Yujie;  Xiao, Qiang;  Xu, Chenghui
  |  收藏  |  浏览/下载：16/0  |  提交时间：2020/07/01
fDiscovery of pyrazole-thiophene derivatives as highly Potent, orally active Akt inhibitors 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 72-85
作者:  Zhan, Wenhu;  Che, Jinxin;  Xu, Lei;  Wu, Yizhe;  Hu, Xiaobei
  |  收藏  |  浏览/下载：20/0  |  提交时间：2020/07/01
Discovery of 3,4,6-Trisubstituted Piperidine Derivatives as Orally Active, Low hERG Blocking Akt Inhibitors via Conformational Restriction and Structure-Based Design 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 15, 页码: 7264-7288
作者:  Dong, Xiaowu;  Zhan, Wenhu;  Zhao, Mengting;  Che, Jinxin;  Dai, Xiaoyang
  |  收藏  |  浏览/下载：26/0  |  提交时间：2020/07/01
Supramolecular Coordination-Directed Reversible Regulation of Protein Activities at Epigenetic DNA Marks 期刊论文  OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2018, 卷号: 140, 期号: 46, 页码: 15842-15849
作者:  Xiong, Wei;  Wang, Shao-Ru;  Wang, Jia-Qi;  Fu, Bo-Shi;  Chen, Kun
  |  收藏  |  浏览/下载：51/0  |  提交时间：2019/06/20