中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [9]
云南天文台 [5]
国家天文台 [3]
武汉病毒研究所 [3]
金属研究所 [2]
国家空间科学中心 [2]
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OAI收割 [26]
iSwitch采集 [4]
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期刊论文 [25]
专利 [5]
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2024 [1]
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天文和天体物理 [1]
天文学::射电天文学 [1]
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Generic protein-ligand interaction scoring by integrating physical prior knowledge and data augmentation modelling
期刊论文
OAI收割
NATURE MACHINE INTELLIGENCE, 2024, 页码: 21
作者:
Cao, Duanhua
;
Chen, Geng
;
Jiang, Jiaxin
;
Yu, Jie
;
Zhang, Runze
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/07/12
Tetrandrine synergizes with MAPK inhibitors in treating KRAS-mutant pancreatic ductal adenocarcinoma via collaboratively modulating the TRAIL-death receptor axis
期刊论文
OAI收割
PHARMACOLOGICAL RESEARCH, 2023, 卷号: 197, 页码: 12
作者:
Tang, Shuai
;
Duan, Yichen
;
Yuan, Tao
;
Hu, Yutinh
;
Yuan, Liang
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2023/12/11
KRAS
Pancreatic ductal adenocarcinoma
MAPK pathway
Tetrandrine
TRAIL
Death receptors
Computing the relative binding affinity of ligands based on a pairwise binding comparison network
期刊论文
OAI收割
Nature computational science, 2023, 卷号: 3, 期号: 10, 页码: 860-872
作者:
Yu, Jie
;
Li, Zhaojun
;
Chen, Geng
;
Kong, Xiangtai
;
Hu, Jie
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/03/26
Discovery of Novel Pyrrolo[2,3-d]pyrimidine-based Derivatives as Potent JAK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 2, 页码: 1243-1264
作者:
Liang, Xuewu
;
Tang, Shuai
;
Liu, Xuyi
;
Liu, Yingluo
;
Xu, Qifu
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2022/06/15
Structural insights into the activation of human calcium-sensing receptor
期刊论文
OAI收割
ELIFE, 2021, 卷号: 10, 页码: 24
作者:
Chen, Xiaochen
;
Wang, Lu
;
Cui, Qianqian
;
Ding, Zhanyu
;
Han, Li
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2021/11/04
G-protein-coupled receptor
calcium-sensing receptor
cryo-electron microscopy
calcium ions
nanobody
CaSR
GPCR
cryo-EM
None
Corrosion of RE2Si2O7 (RE = Y, Yb, and Lu) environmental barrier coating materials by molten calcium-magnesium-alumino-silicate glass at high temperatures
期刊论文
OAI收割
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY, 2019, 卷号: 39, 期号: 14, 页码: 4245-4254
作者:
Tian, Zhilin
;
Ren, Xiaomin
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/02/02
Rare earth silicates
Corrosion
Calcium-magnesium-alumino-silicate
Environmental barrier coating materials
Corrosion of RE2Si2O7 (RE = Y, Yb, and Lu) environmental barrier coating materials by molten calcium-magnesium-alumino-silicate glass at high temperatures
期刊论文
OAI收割
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY, 2019, 卷号: 39, 期号: 14, 页码: 4245-4254
作者:
Tian, Zhilin
;
Ren, Xiaomin
;
Lei, Yiming
;
Zheng, Liya
;
Geng, Wanrong
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2021/02/02
Rare earth silicates
Corrosion
Calcium-magnesium-alumino-silicate
Environmental barrier coating materials
Histone marks interplay at LIFR enhancer determines the response to HDAC inhibitors in breast cancer
期刊论文
OAI收割
CANCER RESEARCH, 2019, 卷号: 79, 期号: 13, 页码: 2
作者:
Wang, Xiaomin
;
Xu, Jun
;
Ding, Jian
;
Geng, Meiyu
;
Huang, Min
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/07/01
Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 15
作者:
Jin, Nan
;
Bi, Aiwei
;
Lan, Xiaojing
;
Xu, Jun
;
Wang, Xiaomin
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2020/07/01
Vb_lspm-01: a novel myovirus displaying pseudolysogeny in lysinibacillus sphaericus c3-41
期刊论文
iSwitch采集
Applied microbiology and biotechnology, 2018, 卷号: 102, 期号: 24, 页码: 10691-10702
作者:
Geng, Peiling
;
Wan, Xiaofu
;
Cheng, Jiao
;
Yuan, Zhiming
;
Hu, Xiaomin
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2019/05/08
Lysinibacillus sphaericus
Myovirus
Lysis
Lysogeny
Pseudolysogeny
Vb_lspm-01