机构

• 上海药物研究所 [11]
• 西安光学精密机械研究... [9]
• 广州地球化学研究所 [1]
• 中国科学院大学 [1]
• 地球化学研究所 [1]

采集方式

• OAI收割 [22]
• iSwitch采集 [1]

内容类型

• 期刊论文 [20]
• 会议论文 [3]

发表日期

• 2024 [1]
• 2023 [3]
• 2022 [2]
• 2021 [5]
• 2020 [1]
• 2019 [4]
• 更多

学科主题

• 环境地球化学 [1]

筛选

浏览/检索结果: 共23条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Development of Potent MALT1 Inhibitors Featuring a Novel "2-Thioxo-2,3-dihydrothiazolo[4,5-d]pyrimidin-7(6H)-one" Scaffold for the Treatment of B Cell Lymphoma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2884-2906 作者:  Liang, Xuewu;  Yu, Haolan;  Liang, Renwen;  Feng, Zhuanghui;  Saidahmatov, Abdusaid   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/04/09 Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933 作者:  Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/01/26 derivatives  Antitumor drug development  Potential AXL inhibitor  Antitumor activity  Structure-based drug design  Fused-pyrazolone carboxamide   The new direction of drug development: Degradation of undruggable targets through targeting chimera technology 期刊论文  OAI收割 MEDICINAL RESEARCH REVIEWS, 2023, 页码: 54 作者:  Liang, Xuewu;  Ren, Hairu;  Han, Fengyang;  Liang, Renwen;  Zhao, Jiayan   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/01/16 chimeric design  degradation System  PROTAC  targeted degradation technology  undruggable targets   Construction of Diversified Penta-Spiro-Heterocyclic and Fused-Heterocyclic Frameworks with Potent Antitumor Activity 期刊论文  OAI收割 CHEMISTRY-A EUROPEAN JOURNAL, 2023, 页码: 7 作者:  Liu, Qi;  Liu, Xuyi;  Li, Yazhou;  Zhou, Yu;  Zhao, Linxiang   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/10/17 spiro  fused-heterocyclic frameworks  substrate- and pH- controlled strategies  C-H activation  [4+1] and [4+2] annulation  antitumor  indazolone   Discovery of Novel Imidazo[4,5-c]quinoline Derivatives to Treat Inflammatory Bowel Disease (IBD) by Inhibiting Multiple Proinflammatory Signaling Pathways and Restoring Intestinal Homeostasis 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 21 作者:  Liang, Xuewu;  Xie, Yongle;  Liu, Xuyi;  Xu, Hui;  Ren, Hairu   |  收藏  |  浏览/下载：25/0  |  提交时间：2022/11/11 Discovery of Novel Pyrrolo[2,3-d]pyrimidine-based Derivatives as Potent JAK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 2, 页码: 1243-1264 作者:  Liang, Xuewu;  Tang, Shuai;  Liu, Xuyi;  Liu, Yingluo;  Xu, Qifu   |  收藏  |  浏览/下载：38/0  |  提交时间：2022/06/15 I-2-induced cascade cyclization and dearomatization of indoles for the highly efficient synthesis of iodinated and vinylic spiroindolenines 期刊论文  OAI收割 GREEN CHEMISTRY, 2021, 卷号: 23, 期号: 22, 页码: 9165-9171 作者:  Wei, Xiaohui;  Liang, Xuewu;  Li, Yazhou;  Liu, Qi;  Liu, Xuyi   |  收藏  |  浏览/下载：13/0  |  提交时间：2021/12/16 Identification of Novel Fused Heteroaromatics-Based MALT1 Inhibitors by High-Throughput Screening to Treat B Cell Lymphoma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 13, 页码: 9217-9237 作者:  Liang, Xuewu;  Sun, Chenxia;  Li, Chunpu;  Yu, Haolan;  Wei, Xiaohui   |  收藏  |  浏览/下载：18/0  |  提交时间：2021/08/17 Solving, analyzing, manufacturing, and experimental testing of thickness distribution for a cycloid-like variable curvature mirror 期刊论文  OAI收割 Optics Express, 2021, 卷号: 29, 期号: 12, 页码: 18010-18025 作者:  Xie, Xiaopeng;  Xu, Liang;  Wang, Yongjie;  Shen, Le;  Fan, Xuewu   |  收藏  |  浏览/下载：47/0  |  提交时间：2021/06/21 MALT1 as a promising target to treat lymphoma and other diseases related to MALT1 anomalies 期刊论文  OAI收割 MEDICINAL RESEARCH REVIEWS, 2021, 页码: 35 作者:  Liang, Xuewu;  Cao, YiChun;  Li, Chunpu;  Yu, Haolan;  Yang, Chenghua   |  收藏  |  浏览/下载：17/0  |  提交时间：2021/05/24 DLBCL  MALT lymphoma  MALT1  MALT1 inhibitors  NF‐  κ  B pathway