中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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Simplified Method for Natural Laminar Flow Prediction on Supersonic Highly Swept Wings
期刊论文
OAI收割
AIAA JOURNAL, 2025, 页码: 14
作者:
Nie, Han
;
Liu, Wen
;
Zhang, Chen-An
;
Liu, Yang
;
Guo, Shuai-Qi
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/11/03
Mean Aerodynamic Chord
Friction Drag Reduction
Wing Configurations
Laminar to Turbulent Transition
Supersonic Aircraft
Drag Reduction
Boundary Layer Transition
Laminar Turbulent Transition
Linear Stability Analysis
Symbolic Artificial Intelligence
Primary Amine-Based Photoclick Chemistry: From Concept to Diverse Applications in Chemical Biology and Medicinal Chemistry
期刊论文
OAI收割
ACCOUNTS OF CHEMICAL RESEARCH, 2025, 卷号: 58, 期号: 13, 页码: 1963-1981
作者:
Hu, Hao
;
Nie, Hui-Jun
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/08/20
Visible-Light-Controlled Lysine-Selective Crosslinking Decodes Protein Complexes and Dynamic Interactomes in Live Cells
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 15
作者:
Xu, Yali
;
Hu, Hao
;
Ran, Yu
;
Zhao, Wensi
;
Guo, An-Di
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/08/20
Chemoproteomics
Molecular glue degraders
Photo-crosslinking
Protein-protein interactions
Targeted protein degradation
Cross-Linking Profiling of Molecular Glue Degrader-Induced E3 Ligase Interactome to Expand Target Space
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 13
作者:
Xu, Yali
;
Zhao, Wensi
;
Nie, Hui-Jun
;
Wang, Jiamin
;
Fu, Jingjing
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2025/05/27
Chemoproteomics
Genetic code expansion
Molecular glue degrader
Photo-crosslinking
Targeted protein degradation
π-HuB: the proteomic navigator of the human body
期刊论文
OAI收割
NATURE, 2024, 卷号: 636, 期号: 8042, 页码: 322-331
作者:
He, Fuchu
;
Aebersold, Ruedi
;
Baker, Mark S.
;
Bian, Xiuwu
;
Bo, Xiaochen
  |  
收藏
  |  
浏览/下载:100/0
  |  
提交时间:2025/04/01
Discovery of a Potent, selective and orally bioavailable CDK9 degrader for targeting transcription regulation in Triple-Negative breast cancer
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 153, 页码: 16
作者:
Nie, Hui-Jun
;
Li, Ben-Fu
;
Sun, Jingya
;
Yuan, Yali
;
Zhang, Zhi-Gao
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2024/11/26
Triple-negative breast cancer
Targeting transcription regulation
Orally bioavailable degrader
PROTAC
Cyclin-dependent Kinase 9
Target Identification and Mechanistic Characterization of Indole Terpenoid Mimics: Proper Spindle Microtubule Assembly Is Essential for Cdh1-Mediated Proteolysis of CENP-A
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 14
作者:
Peng, Yan
;
Zhang, Yumeng
;
Fang, Ruan
;
Jiang, Hao
  |  
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2024/07/12
Cdh1
CENP-A regulation
colchicine-binding site inhibitor
indole terpenoid
target identification
Accelerating PROTACs Discovery Through a Direct-to-Biology Platform Enabled by Modular Photoclick Chemistry
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 12
作者:
Yan, Ke-Nian
;
Nie, Yong-Qiang
;
Wang, Jia-Yu
;
Yin, Guang-Liang
;
Liu, Qia
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2024/05/31
High-throughput chemical synthesis
modular synthesis
photoclick chemistry
PROTACs library
targeted protein degradation
Tumor-targeted PROTAC prodrug nanoplatform enables precise protein degradation and combination cancer therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12
作者:
Zou, Zhi-feng
;
Yang, Lei
;
Nie, Hui-jun
;
Gao, Jing
;
Lei, Shu-min
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2024/05/22
proteolysis-targeting chimeras
tumor-targeted delivery
precise protein degradation
combination therapy
triple-negative breast cancer
Spatiotemporal and direct capturing global substrates of lysine-modifying enzymes in living cells
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2024, 卷号: 15, 期号: 1, 页码: 15
作者:
Hu, Hao
;
Hu, Wei
;
Guo, An-Di
;
Zhai, Linhui
;
Ma, Song
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2024/05/07