中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [21]
计算技术研究所 [3]
金属研究所 [2]
昆明植物研究所 [1]
合肥物质科学研究院 [1]
采集方式
OAI收割 [28]
内容类型
期刊论文 [27]
学位论文 [1]
发表日期
2024 [2]
2022 [2]
2021 [4]
2019 [1]
2018 [2]
2016 [5]
更多
学科主题
计算机应用 [1]
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浏览/检索结果:
共28条,第1-10条
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Berberine Derivative B68 Promotes Tumor Immune Clearance by Dual-Targeting BMI1 for Senescence Induction and CSN5 for PD-L1 Degradation
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 21
作者:
Hu, Hongmei
;
Wang, Qun
;
Yu, Dianping
;
Tao, Xiaoyu
;
Guo, Mengmeng
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/02/28
BMI1
colorectal cancer
CSN5
PD-L1
tumor cell senescence
Rh(III)-catalyzed late-stage C-H alkenylation and macrolactamization for the synthesis of cyclic peptides with unique Trp(C7)-alkene crosslinks
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2024, 卷号: 35, 期号: 8, 页码: 8
作者:
Hu, Shulei
;
Zhang, Yu
;
Xie, Xiong
;
Li, Luhan
;
Chen, Kaixian
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/11/05
C -H functionalization
Rh(III)-catalyzed
Alkenylation
Cyclic peptides
Macrolactamization
Discovery of Small-Molecule Degraders of the CDK9-Cyclin T1 Complex for Targeting Transcriptional Addiction in Prostate Cancer
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 16, 页码: 11034-11057
作者:
Li, Jiacheng
;
Liu, Ting
;
Song, Yuanli
;
Wang, Mingyu
;
Liu, Liping
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/03/21
L-5-hydroxytryptophan promotes antitumor immunity by inhibiting PD-L1 inducible expression
期刊论文
OAI收割
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 卷号: 10, 期号: 6, 页码: 14
作者:
Huang, Jing
;
Wang, Xiaobo
;
Li, Bing
;
Shen, Shiyu
;
Wang, Ruina
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2022/08/16
Immunotherapy
Immune Evation
T-Lymphocytes
Translational Medical Research
Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 11
作者:
Fan, Shijie
;
Yue, Liyan
;
Wan, Wei
;
Zhang, Yuanyuan
;
Zhang, Bidong
  |  
收藏
  |  
浏览/下载:111/0
  |  
提交时间:2021/12/16
covalent modification
probes
proteome
LC3
post-translational modification
Expert consensus on thermal ablation therapy of pulmonary subsolid nodules (2021 Edition)
期刊论文
OAI收割
JOURNAL OF CANCER RESEARCH AND THERAPEUTICS, 2021, 卷号: 17
作者:
Ye, Xin
;
Fan, Weijun
;
Wang, Zhongmin
;
Wang, Junjie
;
Wang, Hui
  |  
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2022/03/21
Ground-glass nodule
lung cancer screening
pulmonary subsolid nodules
thermal ablation
Dynamics of Post-Translational Modification Inspires Drug Design in the Kinase Family
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15111-15125
作者:
Zhang, Huimin
;
He, Jixiao
;
Hu, Guang
;
Zhu, Fei
;
Jiang, Hao
  |  
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2022/01/04
Discovery of a subtype-selective, covalent inhibitor against palmitoylation pocket of TEAD3
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 10, 页码: 3206-3219
作者:
Lu, Tian
;
Li, Yong
;
Lu, Wenchao
;
Spitters, Twgm
;
Fang, Xueyu
  |  
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2021/12/01
Hippo pathway
TEAD3
Covalent inhibitor
Palmitoylation inhibitor
The dynamic conformational landscape of the protein methyltransferase SETD8
期刊论文
OAI收割
ELIFE, 2019, 卷号: 8, 页码: 76
作者:
Chen, Shi
;
Wiewiora, Rafal P.
;
Meng, Fanwang
;
Babault, Nicolas
;
Ma, Anqi
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
Rational design of 5-((1H-imidazol-1-yl)methyl)quinolin-8-ol derivatives as novel bromodomain-containing protein 4 inhibitors
期刊论文
OAI收割
European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 281-294
作者:
Xing, Jing
;
Zhang, Rukang
;
Jiang, Xiangrui
;
Hu, Tianwen
;
Wang, Xinjun
  |  
收藏
  |  
浏览/下载:101/0
  |  
提交时间:2019/01/08