中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
地理科学与资源研究... [11]
上海药物研究所 [6]
武汉植物园 [5]
地质与地球物理研究所 [3]
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期刊论文 [42]
学位论文 [2]
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2024 [3]
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2021 [4]
2020 [8]
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Biology [1]
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Discovery of novel CDK9 inhibitor with tridentate ligand: Design, synthesis and biological evaluation
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 150, 页码: 12
作者:
Zhong, Ye
;
Xu, Jing
;
Ding, Shaoyue
;
Cao, Huiying
;
Zhang, Yufei
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/08/22
CDK9
Inhibitor
Colorectal cancer
Apoptosis
Tridentate ligand
Discovery and Optimization of Novel Nonbile Acid FXR Agonists as Preclinical Candidates for the Treatment of Inflammatory Bowel Disease
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 7, 页码: 5642-5661
作者:
Li, Yuan
;
Xu, Tingting
;
Zhao, Yue
;
Zhang, Hui
;
Liu, Zesheng
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/05/07
Identification of a Novel Selective CDK9 Inhibitor for the Treatment of CRC: Design, Synthesis, and Biological Activity Evaluation
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 6, 页码: 4739-4756
作者:
Zhong, Ye
;
Xu, Jing
;
Zhou, Ruochen
;
Tang, Li
;
Ding, Shaoyue
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/05/07
Structure basis of two nanobodies neutralizing SARS-CoV-2 Omicron variant by targeting ultra-conservative epitopes
期刊论文
OAI收割
JOURNAL OF STRUCTURAL BIOLOGY, 2023, 卷号: 215, 期号: 3, 页码: 9
作者:
Sun, Zengchao
;
Wang, Lu
;
Li, Lingyun
;
Sun, Yili
;
Zhang, Daizhou
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/10/17
SARS-CoV-2 virus
Receptor -binding domain
Nanobody
Crystal structure
Conservative binding epitope
Bi-paratopic nanobodies
Sodium butyrate activates HMGCS2 to promote ketone body production through SIRT5-mediated desuccinylation
期刊论文
OAI收割
FRONTIERS OF MEDICINE, 2023, 页码: 13
作者:
Xu, Yanhong
;
Ye, Xiaotong
;
Zhou, Yang
;
Cao, Xinyu
;
Peng, Shiqiao
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/04/10
sodium butyrate
succinylation
HMGCS2
ketogenesis
SIRT5
Glycosyltransferase-related long non-coding RNA signature predicts the prognosis of colon adenocarcinoma
期刊论文
OAI收割
FRONTIERS IN ONCOLOGY, 2022, 卷号: 12
作者:
Zhang, Jiawei
;
Wu, Yinan
;
Mu, Jiayi
;
Xin, Dijia
;
Wang, Luyao
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2022/12/22
colorectal cancer
glycosyltransferase
lncRNAs
risk model
overall survival
The adverse inflammatory response of tobacco smoking in COVID-19 patients: biomarkers from proteomics and metabolomics
期刊论文
OAI收割
JOURNAL OF BREATH RESEARCH, 2022, 卷号: 16, 期号: 4, 页码: 46002-1-11
作者:
Cui, Tenglong
;
Miao, Gan
;
Jin, Xiaoting
;
Yu, Haiyi
;
Zhang, Ze
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/02/06
smoking
COVID-19
biomarkers
proteomics
metabolomics
Spatiotemporal Variation in Rainfall Erosivity and Correlation with the ENSO on the Tibetan Plateau since 1971
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2021, 卷号: 18, 期号: 21, 页码: 24
作者:
Cui, Bohao
;
Zhang, Yili
;
Liu, Linshan
;
Xu, Zehua
;
Wang, Zhaofeng
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/09/21
rainfall erosivity
soil erosion
spatiotemporal variation
ENSO
Tibetan Plateau
Spatiotemporal Variation in Rainfall Erosivity and Correlation with the ENSO on the Tibetan Plateau since 1971
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2021, 卷号: 18, 期号: 21, 页码: 24
作者:
Cui, Bohao
;
Zhang, Yili
;
Liu, Linshan
;
Xu, Zehua
;
Wang, Zhaofeng
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/09/21
rainfall erosivity
soil erosion
spatiotemporal variation
ENSO
Tibetan Plateau
Species packing and the latitudinal gradient in beta-diversity
期刊论文
OAI收割
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2021, 卷号: 288, 期号: 1948
作者:
Cao, Ke
;
Condit, Richard
;
Mi, Xiangcheng
;
Chen, Lei
;
Ren, Haibao
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2023/02/24
beta-diversity
gamma-diversity
sampling bias
latitude
species packing
niche specialization