中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [58]
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期刊论文 [304]
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Discovery of Preclinical Candidate AD1058 as a Highly Potent, Selective, and Brain-Penetrant ATR Inhibitor for the Treatment of Advanced Malignancies
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12735-12759
作者:
Liu, Zhi
;
Jiang, Kailong
;
Liu, Yan
;
Li, Junfei
;
Huang, Siqi
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/09/26
Modular Biomimetic Strategy Enables Discovery and SAR Exploration of Oxime Macrocycles as Influenza A Virus (H1N1) Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 10, 页码: 8201-8224
作者:
Xu, Dandan
;
Gong, Ying
;
Zhang, Lianju
;
Xiao, Fu
;
Wang, Xinran
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2024/06/27
Nutrient budgets and biogeochemical dynamics in the coastal regions of northern Beibu Gulf, South China Sea: Implication for the severe impact of human disturbance
期刊论文
OAI收割
MARINE ENVIRONMENTAL RESEARCH, 2024, 卷号: 197, 页码: 106447
作者:
Guo, Jing
;
Yang, Fei
;
Costa Jr, Ozeas S.
;
Yan, Xiaomin
;
Wu, Man
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/06/17
Nutrient budgets
Nutrient fluxes
Nutrient biogeochemistry
LOICZ model
Northern Beibu Gulf
一种耐腐蚀耐磨损低摩擦碳复合薄膜的制备方法及其在滚动轴承表面的应用
专利
OAI收割
专利号: 无, 申请日期: 2024-01-01,
作者:
李红轩
;
刘晓红
;
吉利
;
许文举
;
赵旭
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/12/23
Sources and transport of CO2 in the karst system of Jiguan Cave, Funiu Mountains, China
期刊论文
OAI收割
Science of The Total Environment, 2024, 卷号: 918, 页码: 170507
作者:
Yidong Li
;
Yan Yang
;
Xianguo Wang
;
Weijun Luo
;
Jingyao Zhao
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/03/27
Near-Infrared Organic Photodetectors toward Skin-Integrated Photoplethysmography-Electrocardiography Multimodal Sensing System
期刊论文
OAI收割
ADVANCED SCIENCE, 2023, 页码: 14
作者:
Lou, Zirui
;
Tao, Jun
;
Wei, Binbin
;
Jiang, Xinyu
;
Cheng, Simin
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/01/07
flexible (opto)electronics
multimodal biosensing
near-infrared organic photodetectors
skin-integrated electronics
Tetrandrine synergizes with MAPK inhibitors in treating KRAS-mutant pancreatic ductal adenocarcinoma via collaboratively modulating the TRAIL-death receptor axis
期刊论文
OAI收割
PHARMACOLOGICAL RESEARCH, 2023, 卷号: 197, 页码: 12
作者:
Tang, Shuai
;
Duan, Yichen
;
Yuan, Tao
;
Hu, Yutinh
;
Yuan, Liang
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/12/11
KRAS
Pancreatic ductal adenocarcinoma
MAPK pathway
Tetrandrine
TRAIL
Death receptors
Inhibiting sorting nexin 10 promotes mucosal healing through SREBP2-mediated stemness restoration of intestinal stem cells
期刊论文
OAI收割
SCIENCE ADVANCES, 2023, 卷号: 9, 期号: 35, 页码: 17
作者:
Bao, Weilian
;
You, Yan
;
Ni, Jiahui
;
Hou, Hui
;
Lyu, Jiaren
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/12/08
Investigation of the enhanced oil recovery mechanism of CO2 synergistically with nanofluid in tight glutenite
期刊论文
OAI收割
ENERGY, 2023, 卷号: 273, 期号: -, 页码: -
作者:
Xu, Liang
;
Li, Qi
;
Myers, Matthew
;
Cao, Xiaomin
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/08/02
Tight glutenite
Huff -n -puff experiment
Nanofluid
Carbon dioxide
Enhance oil recovery (EOR)
Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2601-2612
作者:
Wang, Xiaomin
;
Xu, Jun
;
Sun, Yiming
;
Cao, Siyuwei
;
Zeng, Hanlin
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2023/10/17
HDAC inhibitors
Drug resistance
Histone methylation
Histone acetylation
Epigenetic interplay
Hedgehog pathway
ZIC1
LIFR
Combination therapy
Breast cancer