中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [10]
地理科学与资源研究所 [9]
西北高原生物研究所 [9]
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地球化学研究所 [2]
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OAI收割 [45]
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期刊论文 [44]
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2025 [1]
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2020 [6]
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Conformational restriction enables discovering a series of chroman derivatives as potent and selective NaV1.8 inhibitors with improved pharmacokinetic properties
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 293, 页码: 24
作者:
Li, Na
;
Wang, Linlin
;
Hu, Xinyuan
;
Xu, Haiyan
;
Yang, Bowen
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
Voltage-gated sodium channel 1.8
Conformational restriction
Pharmacokinetic
Structure-activity relationship
Analgesic
Sodium selenite enhances the production of functional proteins and biomass in Chlorella pyrenoidosa 038F by promoting acetate assimilation under heterotrophic cultivation
期刊论文
OAI收割
AQUACULTURE, 2024, 卷号: 589, 页码: 10
作者:
Shangguan, Jingjing
;
Yang, Na
;
Zhang, Litao
;
Liu, Jianguo
;
Li, Yueming
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/08/29
Glutathione peroxidase
Chlorella pyrenoidosa
Sodium selenite
Carbon metabolism
Transcriptome
Gluconeogenesis
Discovery of Novel Pyrimidine-Based Derivatives as Nav1.2 Inhibitors with Efficacy in Mouse Models of Epilepsy
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12912-12931
作者:
He, Guoxue
;
Zheng, Yueming
;
Chang, Shunzhen
;
Wang, Long
;
Yang, Xiaohao
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2024/09/26
Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses
期刊论文
OAI收割
NATURE CHEMICAL BIOLOGY, 2024, 页码: 29
作者:
Zhou, Xiaoyu
;
Zhao, Cheng
;
Xu, Haiyan
;
Xu, Yixiang
;
Zhan, Li
  |  
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2024/03/25
DRAN: Detailed Region-Adaptive Normalization for Conditional Image Synthesis
期刊论文
OAI收割
IEEE Transactions on Multimedia, 2024, 页码: 14
作者:
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2024/05/28
Microstructure evolution and cyclic oxidation performance of Cr2AlC transition layer as active diffusion barrier for Ni-based superalloy and NiCrAlY coating
期刊论文
OAI收割
CORROSION SCIENCE, 2023, 卷号: 222, 页码: 13
作者:
Li, Yang
;
Xu, Jingjun
;
Li, Jingjing
;
Li, Yueming
;
Ma, Ke
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2024/01/08
Cr2AlC
NiCrAlY coating
High-temperature oxidation
Elemental interdiffusion
Diffusion barrier
Discovery of selective NaV1.8 inhibitors based on 5-chloro-2-(4,4-difluor- oazepan-1-yl)-6-methyl nicotinamide scaffold for the treatment of pain
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 12
作者:
Qin, Hui
;
Wei, Aihuan
;
Wang, Yunqi
;
Wang, Linlin
;
Xu, Haiyan
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2023/10/17
Pain
Non-addictive analgesics
Na V 1
8-selective inhibitors
Bicyclic aromatic groups
Characterization of nongxiang- and soy sauce-type distilled grains and their application in enhancing polyunsaturated fatty acid and triacylglyceride production from Chlorella sp. 038F
期刊论文
OAI收割
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, 2023, 卷号: 11, 期号: 3, 页码: 9
作者:
Yang, Na
;
Shangguan, Jingjing
;
Zhang, Litao
;
Li, Yueming
;
Xu, Jianchun
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2023/12/07
Distilled grains
Chlorella sp
038F
Mixotrophic cultivation
Polyunsaturated fatty acid
Triacylglyceride
Design, Synthesis and Bioactivity of [3.3.3]Propellane-Based Voltage-Gated Calcium Channel alpha 2 delta Subunit Ligands
期刊论文
OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2023, 卷号: 43, 期号: 6, 页码: 2226-2238
作者:
He Jinyan
;
Tian Fuyun
;
Wu Qingqing
;
Zheng Yueming
;
Chen Yuting
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2023/10/17
propellane
voltage-gated calcium channel
alpha 2 delta subunit
synthesis
bioactivity
structure-activity relationship
Study on structure-activity relationship (SAR) of simplified mirogabalin derivatives as voltage-gated calcium channel alpha 2 delta ligands for the treatment of chronic neuropathic pain
期刊论文
OAI收割
MEDICINAL CHEMISTRY RESEARCH, 2022, 页码: 26
作者:
Zhang, Yuanwen
;
Zheng, Yueming
;
Wu, Qingqing
;
Tian, Fuyun
;
Ma, Chuanjun
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2023/04/10
Voltage-gated calcium channel
alpha 2 delta subunit
gamma-aminobutyric acid
Mirogabalin
Neuropathic pain
Structure-activity relationship