中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [17]
遥感与数字地球研究所 [6]
地理科学与资源研究所 [5]
计算技术研究所 [2]
长春光学精密机械与物... [1]
中国科学院大学 [1]
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期刊论文 [28]
会议论文 [4]
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2023 [2]
2022 [2]
2021 [1]
2020 [1]
2018 [1]
2017 [5]
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Absorption, Distribution, Metabolism, and Excretion of [
14
C]BS1801, a Selenium-Containing Drug Candidate, in Rats
期刊论文
OAI收割
MOLECULES, 2023, 卷号: 28, 期号: 24, 页码: 16
作者:
Yang, Cheng
;
Xue, Mingzhen
;
He, Yifei
;
Yin, Hanwei
;
Yang, Chen
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/01/26
[C-14]BS1801
BS1801 (butaselen)
tissue distribution
metabolism
mass balance
selenium
Pharmacokinetics, Mass Balance, Tissue Distribution, and Metabolism of [
3
H]Catalpol in Rats: the Main Bioactive Component of
Rehmannia glutinosa
for the Treatment of Ischemic Stroke
期刊论文
OAI收割
CURRENT DRUG METABOLISM, 2023, 页码: 10
作者:
Ge, Xinyu
;
Zheng, Yuandong
;
He, Yifei
;
Chen, Chong
;
Yang, Chen
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/12/08
[H-3]catalpol
Rehmannia glutinosa
mass balance
tissue distribution
metabolism
intestinal flora
ischemic stroke.
Mechanistic Study on the Species Differences in Excretion Pathway of HR011303 in Humans and Rats
期刊论文
OAI收割
DRUG METABOLISM AND DISPOSITION, 2022, 卷号: 50, 期号: 6, 页码: 809-818
作者:
Guo, Zitao
;
Liu, Mengling
;
Meng, Jian
;
Xue, Yaru
;
Huang, Qi
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/08/16
Pharmacokinetics, Mass Balance, and Metabolism of the Novel Urate Transporter 1 Inhibitor [14C]HR011303 in Humans: Metabolism Is Mediated Predominantly by UDP-Glucuronosyltransferase
期刊论文
OAI收割
DRUG METABOLISM AND DISPOSITION, 2022, 卷号: 50, 期号: 6, 页码: 798-808
作者:
Zheng, Yuandong
;
Zhang, Hua
;
Liu, Mengling
;
Li, Guangze
;
Ma, Sheng
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2022/08/16
p Metabolite Identification in the Preclinical and Clinical Phase of Drug Development
期刊论文
OAI收割
CURRENT DRUG METABOLISM, 2021, 卷号: 22, 期号: 11, 页码: 838-857
作者:
Wu, Yali
;
Pan, Lulu
;
Chen, Zhendong
;
Zheng, Yuandong
;
Diao, Xingxing
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2022/06/15
Metabolite identification
drug toxicity
drug exposure
covalent-binding drug
drug safety
natural medicines
Characterization of covalent binding of tyrosine kinase inhibitors to plasma proteins
期刊论文
OAI收割
DRUG METABOLISM AND PHARMACOKINETICS, 2020, 卷号: 35, 期号: 5, 页码: 456-465
作者:
Liu, Xiaoyun
;
Feng, Dan
;
Zheng, Mingyue
;
Cui, Yongmei
;
Zhong, Dafang
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/12/21
Covalent tyrosine kinase inhibitors
Covalent binding
Human serum albumin
Molecular docking
Quantitative calculations
Linear modeling
Species difference
Hydrolytic Metabolism of Cyanopyrrolidine DPP-4 Inhibitors Mediated by Dipeptidyl Peptidases
期刊论文
OAI收割
Drug metabolism and disposition: the biological fate of chemicals, 2018
作者:
Kong, Fandi
;
Pang, Xiaoyan
;
Zhao, Jihui
;
Deng, Pan
;
Zheng, Mingyue
  |  
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2019/01/08
Ecological Niche Modeling Identifies Fine-Scale Areas at High Risk of Dengue Fever in the Pearl River Delta, China
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2017, 卷号: 14, 期号: 6, 页码: 13
作者:
Li, Qiaoxuan
;
Ren, Hongyan
;
Zheng, Lan
;
Cao, Wei
;
Zhang, An
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/09/25
dengue fever
Maxent
socioeconomic factors
environmental conditions
Guangzhou
Foshan
Ecological Niche Modeling Identifies Fine-Scale Areas at High Risk of Dengue Fever in the Pearl River Delta, China
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2017, 卷号: 14, 期号: 6, 页码: 13
作者:
Li, Qiaoxuan
;
Ren, Hongyan
;
Zheng, Lan
;
Cao, Wei
;
Zhang, An
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/09/25
dengue fever
Maxent
socioeconomic factors
environmental conditions
Guangzhou
Foshan
Ecological Niche Modeling Identifies Fine-Scale Areas at High Risk of Dengue Fever in the Pearl River Delta, China
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2017, 卷号: 14, 期号: 6, 页码: 13
作者:
Li, Qiaoxuan
;
Ren, Hongyan
;
Zheng, Lan
;
Cao, Wei
;
Zhang, An
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/09/25
dengue fever
Maxent
socioeconomic factors
environmental conditions
Guangzhou
Foshan