机构

• 上海药物研究所 [32]
• 中国科学院大学 [1]

采集方式

• OAI收割 [32]
• iSwitch采集 [1]

内容类型

• 期刊论文 [33]

发表日期

• 2024 [3]
• 2023 [7]
• 2022 [7]
• 2021 [4]
• 2019 [2]
• 2016 [3]
• 更多

学科主题

筛选

浏览/检索结果: 共33条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Metabolism investigation of the peptide-drug conjugate LN005 in rats using UHPLC-HRMS 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 238, 页码: 11 作者:  Wang, Weiqiang;  Chen, Chong;  Luo, Jing;  Tang, Chongzhuang;  Zheng, Yuandong   |  收藏  |  浏览/下载：23/0  |  提交时间：2024/01/16 LN005  Metabolism  Peptide -drug conjugates  UHPLC-HRMS  Doxorubicin   Metabolite characterisation of the peptide-drug conjugate LN005 in liver S9s by UHPLC-Orbitrap-HRMS 期刊论文  OAI收割 XENOBIOTICA, 2024, 页码: 9 作者:  Yuan, Yali;  Wang, Weiqiang;  Luo, Jing;  Tang, Chongzhuang;  Zheng, Yuandong   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/02/19 peptide-drug conjugate  PDC  LN005  metabolite identification  liver S9s   Development and validation of a sensitive liquid chromatography-tandem mass spectrometry method for the assay of 12 substances in rat plasma and its application to rat pharmacokinetics of Epimedium and Psoraleae Fructus herb pair after oral administration 期刊论文  OAI收割 JOURNAL OF SEPARATION SCIENCE, 2024, 卷号: 47, 期号: 1, 页码: 17 作者:  Wang, Linwei;  Yin, Xiaoying;  Liu, Huan;  Wang, Yangyang;  Li, Zhixiong   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/02/27 compatibility behaviors  Epimedium  LC-MS/MS  pharmacokinetics  Psoraleae Fructus   Absorption, Distribution, Metabolism, and Excretion of [14C]BS1801, a Selenium-Containing Drug Candidate, in Rats 期刊论文  OAI收割 MOLECULES, 2023, 卷号: 28, 期号: 24, 页码: 16 作者:  Yang, Cheng;  Xue, Mingzhen;  He, Yifei;  Yin, Hanwei;  Yang, Chen   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/01/26 [C-14]BS1801  BS1801 (butaselen)  tissue distribution  metabolism  mass balance  selenium   A validated LC-MS/MS method for the quantification of bevacizumab in rat, cynomolgus monkey, and human serum 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023, 卷号: 235, 页码: 11 作者:  Zhou, Ainan;  Yu, Jinghua;  Wu, Yali;  Xue, Hao;  Zhong, Dafang   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/10/17 Monoclonal antibody  Bevacizumab  LC-MS  MS  Surrogate peptide  Pharmacokinetics  Serum   Discovery and Structural Optimization of Covalent ZAP-70 Kinase Inhibitors against Psoriasis 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 15 作者:     |  收藏  |  浏览/下载：9/0  |  提交时间：2023/10/17 Pharmacokinetics, Mass Balance, Tissue Distribution, and Metabolism of [3H]Catalpol in Rats: the Main Bioactive Component of Rehmannia glutinosa for the Treatment of Ischemic Stroke 期刊论文  OAI收割 CURRENT DRUG METABOLISM, 2023, 页码: 10 作者:  Ge, Xinyu;  Zheng, Yuandong;  He, Yifei;  Chen, Chong;  Yang, Chen   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/08 [H-3]catalpol  Rehmannia glutinosa  mass balance  tissue distribution  metabolism  intestinal flora  ischemic stroke.   Discovery of 7H-Pyrrolo[2,3-d]pyrimidine Derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 15 作者:  Wu, Feifei;  Li, Huiyu;  An, Qi;  Sun, Yaoliang;  Yu, Jinghua   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/10/17 Hematopoietic progenitor kinase 1 (HPK1)  Cancer immunotherapy  Inhibitor  T cell   Pharmacokinetics,mass balance,and metabolism of 14C TPN171,a novel PDE5 inhibitor,in humans for the treatment of pulmonary arterial hypertension 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 1, 页码: 221 作者:  He Yifei;  Liu Yin;  Yu Jinghua;  Cheng Huan;  Odilov Abdullajon   |  收藏  |  浏览/下载：15/0  |  提交时间：2023/05/22 TPN171  14CTPN171  PDE5 inhibitor  pulmonary arterial hypertension  healthy volunteers  pharmacokinetics  metabolite identification  mass balance   Covalent Binding Mechanism of Furmonertinib and Osimertinib With Human Serum AlbuminS 期刊论文  OAI收割 DRUG METABOLISM AND DISPOSITION, 2023, 卷号: 51, 期号: 1, 页码: 8-16 作者:  Wu, Yali;  Chen, Lili;  Chen, Jian;  Xue, Hao;  He, Qingfeng   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/03/27