中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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自动化研究所 [69]
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Structural optimization and discovery of high effective isopropanolamine-based TPS1 inhibitors as promising broad-spectrum fungicide candidates
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 290, 页码: 17
作者:
Jiang, Zhiyang
;
Wang, Na
;
Chen, Jinxiu
;
Xu, Huan
;
Zhu, Wenya
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/05/27
Trehalose-6-phosphate synthase
Structural optimization
Isopropanolamine compounds
Inhibitors
Fungicide candidates
A holistic strategy for the in-depth discrimination and authentication of 16 citrus herbs and associated commercial products based on machine learning techniques and non-targeted metabolomics
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY A, 2025, 卷号: 1745, 页码: 12
作者:
Huang, Yu-shi
;
An, Ya-ling
;
Zheng, Yue-yuan
;
Zhao, Wen-jie
;
Song, Chun-qian
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收藏
  |  
浏览/下载:35/0
  |  
提交时间:2025/04/01
Citrus herbs
Discrimination
LC-MS
Machine learning
Differential markers
Comprehensive MALDI mass spectrometry imaging of tumor regions post-neoadjuvant therapy
期刊论文
OAI收割
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2025, 页码: 8
作者:
Xu, Hui
;
Zhang, Qian
;
Yuan, Jie
;
Xu, Jianfeng
;
Sui, Jian
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/04/01
Neoadjuvant chemotherapy
Matrix-assisted laser desorption ionization mass spectrometer
Necrotic region
Spatial metabolomics
Hemodynamic and Pharmacokinetic Interactions of TPN171 with Alcohol in Healthy Male Subjects
期刊论文
OAI收割
CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 2025, 卷号: 18, 期号: 2, 页码: 8
作者:
Cheng, Jie
;
Qian, Hongjie
;
Wang, Yu
;
Liang, Liyu
;
Xu, Wenjing
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/04/01
alcohol
healthy subjects
hemodynamics
PDE5 inhibitor
pharmacokinetics
TPN171
Mantle contributions to global tungsten recycling and mineralization
期刊论文
OAI收割
communications earth & environment, 2025
作者:
Jie-Hua Yang
;
Jing-HuaWu
;
Mei-Fu Zhou
;
Rui-ZhongHu
;
Jun-Hong Zhao
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/07/24
Quantitative Proteomic Study Reveals Amygdalin Alleviates Liver Fibrosis Through Inhibiting mTOR/ PDCD4/JNK Pathway in Hepatic Stellate Cells
期刊论文
OAI收割
DRUG DESIGN DEVELOPMENT AND THERAPY, 2025, 卷号: 19, 页码: 3735-3749
作者:
Huang, Hui
;
Ru, Su-Jie
;
Chen, Jia-Mei
;
Liu, Wei
;
Fang, Shan-Hua
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/07/25
amygdalin
PDCD4
HSC activation
proteomics
Synergistic enhancement of low-temperature strength and toughness in poly(boron-urethane) elastomers via π-π stacking and hydrogen bonding
期刊论文
OAI收割
CHEMICAL ENGINEERING JOURNAL, 2024, 卷号: 503, 期号: 1, 页码: N/A
作者:
Yang, Jing
;
Cao, Pengrui
;
Dou, Qian
;
Guo, Lihe
;
Li, Yanhui
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收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/12/25
π-HuB: the proteomic navigator of the human body
期刊论文
OAI收割
NATURE, 2024, 卷号: 636, 期号: 8042, 页码: 322-331
作者:
He, Fuchu
;
Aebersold, Ruedi
;
Baker, Mark S.
;
Bian, Xiuwu
;
Bo, Xiaochen
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2025/04/01
The influence of steep faults at various avoidance distances on the stability of hard rock caverns: Physical model experiments and DEM simulations
期刊论文
OAI收割
TUNNELLING AND UNDERGROUND SPACE TECHNOLOGY, 2024, 卷号: 154, 页码: 16
作者:
Xu, Huai-sheng
;
Li, Shao-jun
;
Xu, Ding-ping
;
Chen, Shi-jie
;
Feng, Guang-liang
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/06/27
Hard rock cavern
Steep fault-cavern distance
Failure mechanism
Physical model experiment
Discrete element method
Structure-guided design and photochemical synthesis of new carbamo (dithioperoxo)thioates with improved potencies to SARS-CoV-2 3CLpro
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 114, 页码: 9
作者:
Yin, De-Hang
;
Xin, Jie
;
Chen, Shizhao
;
Li, Shuai-Shuai
;
Li, Zi-Ying
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2024/12/11
SARS-CoV-2
Disulfiram
Carbamo(dithioperoxo)thioates
Photochemistry
3CL pro