中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17
作者:
Mo, Jun
;
Wang, Yuxian
;
Pan, Youlu
;
Xiao, Qitao
;
Zhao, Jinyi
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/08/20
Menin
High binding affinity
Anti-proliferation activity
AML
Research progress in the technology of active substance extraction from red algae
期刊论文
OAI收割
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS, 2025, 卷号: 91, 页码: 15
作者:
Qu, Jinqi
;
Liu, Runze
;
Yu, Wensong
;
Li, Wenjun
;
Lu, Chenyang
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/10/13
Cultured red algae
Red algae species
Active substances
Extraction techniques
Application
Artificial kink defects enable high-efficiency degradation of nanocellulose via mechanochemical activation
期刊论文
OAI收割
MATTER, 2025, 卷号: 8, 期号: 9, 页码: 13
作者:
Hou, YuanZhen
;
Han, ZiMeng
;
Zhu, YinBo
;
Xia, Jun
;
Li, JiaHao
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/09/29
Analysis of the shear failure between track slab and CA mortar layer caused by thermal effect for ballastless track
期刊论文
OAI收割
CASE STUDIES IN CONSTRUCTION MATERIALS, 2025, 卷号: 22, 页码: 16
作者:
Zhang, Tao
;
Zhang, Zheyuan
;
Tian, Hongming
;
Lu, Chen
;
Wang, Wei
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2025/06/27
Ballastless track
CA mortar
Constitutive model
Damage analysis
Design and synthesis of GRPR-targeted PET probes based on Dar derivatives for imaging of prostate cancer
期刊论文
OAI收割
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2025, 卷号: 67, 页码: 9
作者:
Luo, Xiangning
;
Luo, Renli
;
Zhou, Yuanyuan
;
Jiang, Yuanpeng
;
Han, Cong
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/08/20
Gastrin-releasing peptide receptor
68Ga
Dar chelator
Positron emission tomography
Imaging probe
Reanalysis Data Sets Underestimate the 1928-29 Summer Precipitation Deficits During the Late-1920s Megadrought in Northern China
期刊论文
OAI收割
GEOPHYSICAL RESEARCH LETTERS, 2025, 卷号: 52, 期号: 11, 页码: 14
作者:
Fang, Congxi
;
Liu, Yu
;
Sun, Changfeng
;
Song, Huiming
;
Su, Lijun
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/08/18
precipitation reconstruction
drought
tree-ring
reanalysis data
Loess Plateau
Discovery of TBK1Molecular Glue Degraders as a Potential Strategy for the Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD)
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 12, 页码: 12862-12880
作者:
Guo, Jing
;
Tang, Haotian
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/08/20
Cbl-b inhibitor NX-1607 activates MAPK/ERK signaling pathway and enhances T-cell activation
期刊论文
OAI收割
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2025, 卷号: 13, 期号: 5, 页码: 18
作者:
Zhu, Wenting
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/08/20
Tumor microenvironment - TME
T cell
Immunotherapy
Immune modulatory
Immune Checkpoint Inhibitor
Development of 3-arylaminothiophenic-2-carboxylic acid derivatives as new FTO inhibitors showing potent antileukemia activities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 289, 页码: 17
作者:
Zhang, Deyan
;
Liu, Lu
;
Li, Ming
;
Hu, Xinyi
;
Zhang, Xi
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/04/24
RNA modification
N 6-methyladenosine
Demethylase FTO
Structure-activity relationship
Antileukemia
From waste to soil: The pivotal role of organic matter in soil aggregate formation under dry and wet conditions
期刊论文
OAI收割
PLANT AND SOIL, 2025, 页码: 17
作者:
Lu, Zijing
;
Wang, Hengshuang
;
Liu, Jiazhi
;
Wang, Zhixiang
;
Song, Shaoxian
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/07/11
Solid waste
Soil organic matter
Soil aggregate
Soil structure